LGD 4033 + RAD140 + YK11 Capsules
LGD 4033 + RAD 140 + YK-11 capsules consists of 15mg LGD 4033, 30mg RAD 140 and 10mg YK-11, totaling 55mg per capsule and 3300mg in total.
Ligandrol is a novel nonsteroidal oral selective androgen receptor modulator currently being investigated in research as a potential treatment for conditions relating to muscle dystrophy and osteoporosis.
Recent studies investigated the effects of LGD 4033 on muscle tissue in ovariectomized rats. A daily dose of LGD was administered and calculated according to body weight of each individual rat at the onset of the study. Results and changes were noted as soon as week 2, the control group having weighed significantly less than rats undergoing LGD treatment. This difference remained until the end of the study, irrespective of LGD treatments. Additionally, the LGD treatments resulted in a higher number of capillaries in all muscles studied. Longer randomized trials and research could potentially evaluate its efficacy in improving physical function and health outcomes in select populations.
|Molar Mass||338.253 g·mol−1|
Testolone, also known as RAD 140, as a research compound is being investigated for its potential ability to enhance muscle hypertrophy. Current studies are examining the preclinical characterization of selective androgen receptor modulators and anabolic activity on male cynomolgus monkeys. To assess anabolic activity, one study examined gross body weight, which we know to be a sensitive marker of anabolic androgen action in young nonhuman primates. The results on animal body weight of 28-day dosing with RAD140 was found to be statistically significant. This shows massive promise in the potential muscular gains brought on by Testolone.
|Molar Mass||393.83 g·mol−1|
A recent study has shown that YK11, a selective androgen receptor myostatin inhibitor, accelerates the expression of Follistatin in mice. Follistatin is a myostatin and activin-binding protein naturally found in the human body and has been used as a treatment for several degenerative muscle diseases. When follistatin levels are raised, myostatin levels will be inhibited. Inhibition of myostatin results in increased muscle mass and improved strength.
This study revealed that mice with low levels of myostatin have twice the amount of muscle mass compared to mice with high levels of myostatin. This shows the massive potential research implications of the strong anabolic effects that YK-11 can possess.
|Molar Mass||430.541 g·mol−1|
|IUPAC Name||methyl (2E)-2-[(8R,9S,10R,13S,14S,17S)-2′-methoxy-2′,13-dimethyl-3-oxospiro[1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-17,5′-1,3-dioxolane]-4′-ylidene]acetate|
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