Mass Construction 2.0
4-Andro is offered in 67mg per ml for 30ml, totaling 2000mg.
4-Andro’s main ingredient, 4-Dehydroepiandrosterone (4-DHEA), is a positional isomer of the DHEA compound. The chemical structural modification of DHEA reduces its thermogenic properties (calorie burning) while increasing its androgenic, anabolic properties and endothelial nitric oxide synthase activity by increasing its binding affinity to muscular receptors. A recent study on the physiological and hormonal influence of androstenedione found that during 12 weeks of androstenedione or androstenediol use, a significant increase in the aromatization by-products estrone and estradiol was observed in research subjects. In the dione group, total testosterone levels significantly increased 16% after 1 month of use, but by the end of 12 weeks, they returned to pre-treatment levels.
|Molar Mass||290,44 g/mol|
Ligandrol is offered in 67mg per ml for 30ml, totaling 2000mg.
Ligandrol is a novel nonsteroidal oral selective androgen receptor modulator currently being investigated in research as a potential treatment for conditions relating to muscle dystrophy and osteoporosis.
Recent studies investigated the effects of LGD 4033 on muscle tissue in ovariectomized rats. A daily dose of LGD was administered and calculated according to body weight of each individual rat at the onset of the study. Results and changes were noted as soon as week 2, the control group having weighed significantly less than rats undergoing LGD treatment. This difference remained until the end of the study, irrespective of LGD treatments. Additionally, the LGD treatments resulted in a higher number of capillaries in all muscles studied. Longer randomized trials and research could potentially evaluate its efficacy in improving physical function and health outcomes in select populations.
|Molar Mass||338.253 g·mol−1|
Mk-677 is offered in 67mg per ml for 30ml, totaling 2000mg.
A recent study set out to investigate the effects of MK-677 as a Ghrelin mimetic on body composition and clinical outcomes in healthy older adults. It was found that MK-677 enhanced fluctuating growth hormone secretion and markedly increased fat free mass over a 12-month period. More extensive research and randomized trials could potentially evaluate its efficacy in improving physical function and health outcomes in select populations. Each MK-677 liquid contains 67mg per ml.
|Molar Mass||528.67 g·mol−1|
|IUPAC Name||2-amino-2-methyl-N-[1-(1-methylsulfonylspiro[2H indole-3,4′-piperidine]-1′-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propenamide|
YK-11 is offered in 33mg per ml for 30ml, totaling 1000mg.
A recent study has shown that YK11, a selective androgen receptor myostatin inhibitor, accelerates the expression of Follistatin in mice. Follistatin is a myostatin and activin-binding protein naturally found in the human body and has been used as a treatment for several degenerative muscle diseases. When follistatin levels are raised, myostatin levels will be inhibited. Inhibition of myostatin results in increased muscle mass and improved strength.
This study revealed that mice with low levels of myostatin have twice the amount of muscle mass compared to mice with high levels of myostatin. This shows the massive potential research implications of the strong anabolic effects that YK-11 can possess. Each YK-11 liquid contains 33mg per ml.
|Molar Mass||430.541 g·mol−1|
|IUPAC Name||methyl (2E)-2-[(8R,9S,10R,13S,14S,17S)-2′-methoxy-2′,13-dimethyl-3-oxospiro[1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-17,5′-1,3-dioxolane]-4′-ylidene]acetate|
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