Nemesis tablets is offered in 2 variants: 25mg RAD 140, 25mg LGD 4033 and 25mg S23 ,totaling 50mg per tablet for 20 tablets or 1000mg in total; and 25mg RAD 140, 25mg LGD 4033 and 25mg S23, totaling 50mg per tablet for 40 tablets or 2000mg in total.
Ligandrol is a novel nonsteroidal oral selective androgen receptor modulator currently being investigated in research as a potential treatment for conditions relating to muscle dystrophy and osteoporosis.
Recent studies investigated the effects of LGD 4033 on muscle tissue in ovariectomized rats. A daily dose of LGD was administered and calculated according to body weight of each individual rat at the onset of the study. Results and changes were noted as soon as week 2, the control group having weighed significantly less than rats undergoing LGD treatment. This difference remained until the end of the study, irrespective of LGD treatments. Additionally, the LGD treatments resulted in a higher number of capillaries in all muscles studied. Longer randomized trials and research could potentially evaluate its efficacy in improving physical function and health outcomes in select populations.
|Molar Mass||338.253 g·mol−1|
Testolone, also known as RAD 140, as a research compound is being investigated for its potential ability to enhance muscle hypertrophy. Current studies are examining the preclinical characterization of selective androgen receptor modulators and anabolic activity on male cynomolgus monkeys. To assess anabolic activity, one study examined gross body weight, which we know to be a sensitive marker of anabolic androgen action in young nonhuman primates. The results on animal body weight of 28-day dosing with RAD140 was found to be statistically significant. This shows massive promise in the potential muscular gains brought on by Testolone.
|Molar Mass||393.83 g·mol−1|
According to the available studies, S23 induced infertility in all rats it was exposed to. These effects are dose-dependent and temporary, meaning the rats regained fertility following treatment. This shows potential of S23 as an oral male contraceptive.
According to the research, S23 subdues serum concentration of luteinizing hormone and follicle-stimulating hormone to produce biphasic effects on spermatogenesis. Additional research and clinical trials should be conducted to determine the efficacy and safety of S23 is as an oral contraceptive.
The above-mentioned study produced other beneficial desirable effects. For instance, researchers observed a stronger affinity to androgen receptors as compared to other popular compounds like Andarine. It also has an ideal anabolic-androgenic ratio allowing it to produce a good number of positive effects without any severe complications. One of those effects was increasing bone mineral density and lean muscle mass.
Therefore, while S23 may be effective as a male birth control pill, it can also be used for other purposes, especially among patients with chronic conditions that lead to muscle wasting.
|Molar Mass||416.76 g·mol−1|
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