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Milk thistle, scientifically known as Silybum marianum and belonging to the Asteraceae family, is a plant found in Southern Europe, Australia, North and South America, Northern Africa, and parts of Asia. It has a long history of use, dating from ancient times to the present day, for treating liver issues and boosting milk production in nursing mothers. The key component of milk thistle is silymarin, a mixture of flavonolignans including silybin A and B, isosilybin A and B, silibinin, silydianin, and silychristin, which are found in its seeds, leaves, and fruits. Among these, silybin stands out for its potent therapeutic effects. Although silymarin isn’t easily absorbed due to low solubility in water, specialized formulations have been developed to enhance its solubility and uptake. [R]

Milk thistle is widely used in potentially treating liver-related issues particularly those with hepatic failure.  The use of milk thistle for healthy liver function has roots dating back centuries, and researchers worldwide have shown substantial interest in its potential benefits, as evident from over 12,000 scientific publications in the last decade. The naming of milk thistle derivatives can be perplexing due to similar compositions and alternate names, but a standardized extract known as silymarin contains several flavonolignans and a flavonoid. Among these, silibinin is the most important, comprising a significant portion of silymarin and being considered the primary active ingredient. [R]

How Does Milk Thistle Work?

Silibinin, a compound within milk thistle, possesses various functions and targets. One well-known mechanism of action is its role as an antioxidant that scavenges and neutralizes harmful free radicals, while also inhibiting lipid peroxidation—a process linked to liver injury. Silibinin is particularly effective in neutralizing smaller free radicals like the hydroxyl radical. In animal studies, supplementation with silibinin led to increased levels of glutathione, an important antioxidant, primarily in the liver and intestines.[R]

Milk thistle extract Investigations:

• Milk thistle liver detox: May treat alcoholic liver disease, acute and chronic viral hepatitis, and toxin-induced liver disorders. [R]
• May help boost breast milk [R]
• May prevent Alzheimer’s disease [R]
• Potential to control diabetes and its complications[R]

Milk Thistle Safety and Side Effects

The most prevalent side effects are headaches and itching, while diarrhea and nausea occur less frequently. No severe or life-threatening adverse effects or fatalities have been attributed to silibinin. Higher doses of silibinin may induce laxative effects, presumably as a result of certain components or increased bile production. [R]

What is an Artichoke extract?

Artichoke extract comes from a plant known as Cynara scolymus, which originally grew in the Mediterranean region but is now cultivated in various parts of the world due to its nutritional and health benefits. In Brazil, it’s commonly referred to as artichoke. This plant has a long history of use in traditional medicine across different cultures. It’s associated with positive effects on bile-related issues, digestion, scurvy, anemia, and even anti-atherosclerosis effects. Beyond being a nutritious food with a slightly bitter taste, it’s also used as a herbal remedy. The extract, derived mainly from the leaves, is used to add bitterness to drinks and is made into herbal teas or medicinal products. The active components of this plant are polyphenolic compounds, primarily found in the leaves rather than the artichoke heads.[R] 

How does Artichoke extract work?

Artichokes may help fight against oxidative stress and block pathways that cause inflammation. It does this by reducing harmful substances like malondialdehyde (MDA) and increasing helpful substances like superoxide dismutase (SOD) and glutathione (GSH) in the liver. When tested on animals, it showed promise in improving liver health and lowering levels of certain markers.

Another way artichoke extract works is by interfering with cholesterol production. It seems to stop the liver from making cholesterol by blocking a specific enzyme called hydroxymethylglutaryl-CoA-reductase. This helps lower cholesterol levels. Certain compounds in artichoke, like chlorogenic acid and luteolin, contribute to these effects. So, even though artichoke might not be a superfood in terms of basic nutrients, its special compounds can have really good effects. [R]

Artichoke Extract Investigations:

• Potential treatment for dyslipidemia [R]
• May help reduce blood sugar [R]
• Potential prevention of arteriosclerosis [R]
• May help prevent oxidative stress-induced hepatotoxicity thus promoting liver health [R]

Artichoke Extract Safety and Side Effects

Longer use of Artichokes may not be safe. It can cause flatulence, gastrointestinal distress, and diarrhea. Occasionally, it may even cause allergies.[R]

Dandelion root extract comes from a plant called Taraxacum officinale, also known as the common dandelion. This plant belongs to a family of plants called Asteraceae. It’s found in many places around the world, even in Europe, North America, and Asia. Dandelion is known for its good things – it’s packed with useful stuff like vitamins (A, C, E, K, B) and minerals (calcium, magnesium, iron, and more).  Dandelion were potentially used to help with kidney, liver, and gallbladder issues for centuries. The good things in dandelions are because of the different chemicals inside them. Some of these chemicals, like sesquiterpene lactones, can fight inflammation and bacteria. Others, like triterpenes and phytosterols, can help keep arteries healthy. Dandelions also have compounds called phenolic compounds, which act like antioxidants, and coumarins, which can help against cancer, inflammation, and bacteria. The roots of dandelions have inulin, which can be good for the gut, blood sugar, and immune system.[R]

What is Dandelion (Taraoxum officinale)(root)?

Dandelion root extract comes from a plant called Taraxacum officinale, also known as the common dandelion. This plant belongs to a family of plants called Asteraceae. It’s found in many places around the world, even in Europe, North America, and Asia. Dandelion is known for its good things – it’s packed with useful stuff like vitamins (A, C, E, K, B) and minerals (calcium, magnesium, iron, and more).  Dandelion were potentially used to help with kidney, liver cells, and gallbladder issues for centuries. The good things in dandelions are because of the different chemicals inside them. Some of these chemicals, like sesquiterpene lactones, can fight inflammation and bacteria. Others, like triterpenes and phytosterols, can help keep arteries healthy. Dandelions also have compounds called phenolic compounds, which act like antioxidants, and coumarins, which can help against cancer, inflammation, and bacteria. The roots of dandelions have inulin, which can be good for the gut, blood sugar, and immune system.[R]

How does Dandelion (Taraoxum officinale)(root) work?

Dandelion has an interesting impact on how our digestive system functions. It can actually slow down certain enzymes responsible for breaking down fats and carbohydrates. This could potentially help in controlling the absorption of nutrients from the diet. Beyond this, dandelion contains substances with antioxidant and anti-inflammatory properties. These properties could be quite helpful for addressing stomach problems. In many cases, digestive issues are linked to factors like inflammation and stress. Dandelion’s ability to reduce inflammation and combat oxidative stress might provide relief for various gastrointestinal problems.[R]

Dandelion Investigations: 

• Potential therapeutic effect against gastrointestinal diseases [R]
• Potential Antioxidant Properties[R]
• May help reduce body weight (anti-obesity) [R]
• Effective in radiation-induced hepatic and testicular tissue injury.[R]
• Potential significant liver benefits as a hepatoprotective effect [R]

Dandelion Safety and Side Effects

Dandelion is generally safe, but it might cause an allergic reaction or mouth sores in some cases. It could also increase stomach acid, causing heartburn, and it might irritate the skin.[R]

What is Beetroot (Beta Vulgaris)(root)?

Beetroot, scientifically known as Beta vulgaris L., is a root vegetable belonging to the Chenopodiaceae family. It originally came from Asia and Europe. This flowering plant is biennial or sometimes perennial, and it comes in various colors from yellow to red. You might hear it called red beet, garden beet, table beet, or just beet.[R]

Beetroot is packed with important nutrients like fiber, vitamin B9 (folate), manganese, potassium, iron, and vitamin C. People not only eat it for its taste but also use it in the food industry for its natural colors, which are safe and harmless. It’s even considered as potential medicinal because it has properties that can fight viruses, and microbes, and act as an antioxidant. There are many potential benefits linked to beetroot, such as supporting healthy blood pressure, boosting athletic performance, aiding digestion, promoting brain health, reducing inflammation, and even having anti-cancer effects. Inside beetroot, you’ll find valuable stuff like amino acids, minerals, flavonoids, and more, which make it a functional food. It’s also safe to use as a preservative in food processing. [R][R]

How does Beetroot work?

Beetroot supplementation can be a helpful way to boost defenses against harmful molecules known as oxidants. Beetroot is loaded with antioxidant compounds, especially betalain pigments, which play a crucial role in safeguarding cells from damage caused by these harmful molecules. Certain components in beetroot, like betanin and betanidin, can prevent damage to important cellular parts caused by oxidative stress. Betanin is the most abundant type of betalain in beetroot, it effectively inhibits the process of lipid peroxidation, which is a type of damage to fats in cells. Beetroot is also packed with other antioxidants like rutin, epicatechin, and caffeic acid, all of which are excellent at neutralizing harmful molecules that cause damage. Moreover, beetroot contains substances like nitrite, which have been found to reduce the formation of damaging molecules and directly get rid of harmful reactive molecules in the body.[R]

Beetroot  Investigations: 

• Potential Antioxidant effect [R][R]
• May Improve cognitive function[R]
• May have  reno-protective property[R]
• May have hepatoprotection effect [R]

Beetroot  Safety and Side Effects

There is no danger associated with beets causing pink or red urine or feces. There are some concerns that beets may lead to decreased calcium levels and potential kidney damage [R]

What is Turmeric (Curcoma longa)(root)?

Turmeric, scientifically known as Curcuma longa, is a plant that belongs to the ginger family called Zingiberaceae. This plant stays green throughout the year and is commonly found in places like India and China in Asia. People in India have been using turmeric for about 2500 years. It’s a plant that grows well in warm parts of the world.[R] It holds a special place as a medicinal plant frequently used in Indian households to address various health concerns. Among plants with medicinal value, those in the Curcuma genus are quite significant for their healing properties. S[R]

How does Turmeric work?

The ethanolic extract of C. longa rhizomes showed a significant hepatoprotective effect. The main constituents of the extract are the flavonoid curcumin and various volatile oils, including tumerone, atlantone, and zingiberene. The hepatoprotective effects of turmeric and curcumin may be due to direct antioxidant and free-radical scavenging mechanisms, as well as the ability to indirectly augment glutathione levels, thereby aiding in hepatic detoxification.The volatile oils and curcumin of C. longa exhibit potent anti-inflammatory effects[R]

Turmeric Investigations: 

• Potential anti-inflamatory effects [R]
• May prevent the progression of liver cirrhosis [R]
• May help with digestive disorders [R]
• May have neuroprotective efficacy [R]

Turmeric Safety and Side Effects

Using turmeric is usually safe, but taking a lot of turmeric or curcumin supplements for a long time might upset the stomach or, in rare cases, cause ulcers.[R]

FAQs

Is Cleanse capsule safe?

In addition to a lack of consistent evidence of direct benefits, the potential long-term effects of using. Cleanse capsules are also unknown. Purerawz sells Cleanse capsules for research purposes only not as dietary supplements.

Where to Buy Cleanse Capsules Online?

PureRawz is the best place to buy Gorged capsules online we offer Cleanse capsules in containing 60 capsules. Some sell this as liver supplements such as Oweli liver detox, but make sure FDA-approved and proper accreditation is in place to ensure safety. 

In order to produce the quality item, we carry the item’s reference materials with every product we sell. Each of our compounds sold comes with an independent, third-party-issued Certificate of Analysis for identification, purity or concentrated natural extract, and concentration. PureRawz don’t sell the modified item

We offer free shipping not just in the USA but worldwide, on all orders or items above $100. You can pay for your purchase through various methods, including PayPal account and Bitcoin. Click on the ‘Reviews’ tab to check out what existing customers have to say about our products and great customer service.

Conclusion

Cleanse capsules offer a unique blend of natural ingredients that could potentially aid liver support and detoxification processes. The formula combines several powerful components, including Milk Thistle, Artichoke Extract, Dandelion Root, Beetroot, Turmeric, etc, all in one convenient capsule. This thoughtful combination aims to provide a holistic approach to liver care. The liver is a vital organ responsible for numerous functions, including detoxification and dealing with fatty liver. Cleanse capsules are designed to potentially activate enzymes and promote detox within the liver and surrounding organs. This capsule contains a variety of beneficial substances, such as zinc, choline, and another proprietary blend of herbal extracts. These ingredients work synergistically to potentially support liver health and rejuvenation.

Milk Thistle, a key component of Cleanse capsules, is known for its hepatoprotective effects. It may aid the liver in neutralizing harmful free radicals and promoting detoxification. Artichoke extract and Dandelion Root offer additional support by potentially blocking inflammation pathways and aiding in optimal liver health. Beetroot and Turmeric, with their antioxidant and anti-inflammatory properties, complete this comprehensive formula.

By combining these ingredients into a single capsule, Cleanse capsules offer a convenient and potentially effective way to enhance overall liver health.

Disclaimer

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).

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