FOXO4-DRI (Proxofim)

Description

What is FOXO4-DRI?

FOXO4-DRI is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53. It is designed to study cellular aging and senescence. It is a modified version of the FOXO4 protein that interacts with p53, a key regulator of cell survival.

Chemical Properties

 

Chemical Name	FOXO4-DRI
Sequence	H-Pyr-Glu-Leu-Arg-Ala-Leu-Asn-Ser-Ser-OH
CAS No	2460055-10-9
Synonym	Forkhead box protein O4, Proxofim, AFX, AFX1
Molecular Formula	C228H388N86D64
Molecular Weight	5358.05 g/mol
Appearance	Solid
Color	White to Off-white
Storage	−80℃ (2 years), −20℃ (1 year)

How does it work?

• FOXO4-DRI is believed to interfere with the FOXO4-p53 interaction.
• Research suggests that the disruption may help remove aged or damaged cells, known as senescent cells.
• These cells do not divide but may contribute to aging and age-related diseases.
• By blocking FOXO4 from binding to p53, FOXO4-DRI may promote the removal of these cells in laboratory settings.

What are the potential benefits of FOXO4-DRI?

FOXO4-DRI is an experimental peptide being studied for its various potential benefits, including the following:

 

• Research suggests that FOXO4-DRI has anti-aging properties that may promote longevity.
• Studies suggest that it may improve tissue repair and regeneration.
• Research indicates that it may protect neurons, which reduces the risk of neurodegenerative diseases like Alzheimer’s.
• Preclinical trials suggest that FOXO4-DRI may support muscle regeneration and recovery, benefiting age-related muscle loss.
• It could also improve heart health by reducing vascular aging and arterial stiffness.

 

Note: This product is intended for research purposes and is not approved for human use.

Research on FOXO4-DRI

Anti-aging and Longevity

Research suggests that FOXO4-DRI may help clear senescent cells, reducing cellular aging and promoting tissue regeneration. Targeting the FOXO4-DRI interaction may extend lifespan and improve overall health.

 

Studies indicate that it could potentially improve organ function and resistance to age-related diseases. This peptide shows promise in enhancing longevity through cellular rejuvenation.

Cognitive Health

FOXO4-DRI may support brain health by reducing cellular senescence in neural tissues. Research indicates potential benefits in protecting against age-related cognitive decline and neurodegenerative diseases.

 

It may enhance brain plasticity, memory retention, and overall cognitive function. These findings highlight its role in preserving mental sharpness with age.

Enhanced Muscle Recovery

Studies suggest that FOXO4-DRI may aid muscle regeneration by eliminating senescent cells that hinder recovery. It may enhance muscle repair, strength, and endurance, particularly in aging individuals.

 

By promoting healthy cell turnover, it may support better physical performance and resilience. This makes it a promising candidate for muscle recovery and anti-fatigue applications.

Cardiovascular Protection

FOXO4-DRI may help protect heart health by reducing cellular damage in vascular tissues. Research indicates it may improve arterial function and reduce the risk of age-related cardiovascular diseases.

 

By preventing senescence in heart cells, it could support better circulation and cardiac efficiency. This peptide holds potential for maintaining cardiovascular health as we age.

Where can I buy FOXO4-DRI online for research purposes?

If you are looking to buy FOXO4-DRI for research purposes, PureRawz is a trustworthy source.

We provide reference materials with every product we sell. A Certificate of Analysis is available for reference, providing information on identification, purity, and concentration.

Is it legal?

FOXO4-DRI is considered legal for research purposes. It is not considered safe and is not approved by the FDA for human or veterinary use. Further studies are required to understand its effectiveness.

FAQs

Is FOXO4-DRI safe for human consumption?

No, FOXO4-DRI is strictly for laboratory research. It is not approved by the FDA for human or veterinary use.

What are the side effects of FOXO4-DRI?

The side effects of this compound have not been fully studied, as it is intended for research purposes only. However, some potential side effects include allergic reactions, fatigue, or weakness. More research is required to confirm its safety.

What is the shelf life of FOXO4-DRI?

The shelf life of FOXO4-DRI is typically 12-24 months when stored in a cool, dry place. Proper storage helps maintain stability and potency.

How to store FOXO4-DRI?

It is best to store this product in a cool, dry place away from direct sunlight. This helps extend the shelf life of the product.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co

 

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human usage.