Peptides

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Peptides 101

What Are Peptides?

Peptides are smaller versions of proteins. They are made up of short chains of amino acids, usually somewhere between 2 and 40.

Peptides can sometimes be confused with proteins. While both of them are made up of amino acids and naturally found in the body, peptides contain far fewer amino acids.

Furthermore, peptides are much easier for the body to consume than proteins, mainly because they are smaller and are easier to break down. This enables them to quickly penetrate the skin and intestines, entering the bloodstream more easily.

At the time of writing, human consumption of peptides is banned and should only be used for research purposes. Still, as multiple animal studies have shown, peptides hold immense therapeutic potential due to their beneficial effects on the body.

What Do Peptides Do?

Natural peptides are involved in a variety of processes in your body.

Research has shown that they may lower high blood pressure, reduce inflammation in the body and stimulate muscle growth. They can also help build up a stronger skin barrier, reduce fine lines and wrinkles and give you a more elastic skin. [R] [R]

It is important to note that only natural peptides are proven to offer these effects. Synthetic or biosynthetic peptides are banned by the Food and Drug Administration (FDA) for over-the-counter self-treatment. It is also illegal to purchase peptides in dietary supplements.

Are Peptides Safe?

Health experts claim that peptides are unlikely to cause serious side effects in healthy individuals. That is due to the fact that everyday foods contain peptides. You can get your daily dose of peptides from natural foods, including meat, fish, lentils, beans, and wheat. [R]   

In one clinical study, 69 women aged 35-55 years were randomized to receive 2.5g or 5.0g of collagen hydrolysate (CH) peptide or placebo once daily for 8 weeks, with 23 subjects being allocated to each treatment group. No side effects were noted throughout the study. [R]

What is the Difference between Peptides and SARMs?

The major difference between peptides and selective androgen receptor modulators is that while SARMs are synthetic non-steroidal compounds, peptides are short chains of amino acids (usually 2 – 40) naturally produced in the body.

Types of Peptides

Based on the mode of action, different peptides are categorized into different groups. While some have increased muscle mass in animal studies, others have reduced male-pattern baldness in mice. Still others have stimulated fat loss in clinical trials. Here are the various types of USA research peptides:

BPC-157

Body Protection Compound 157 is a synthetic penta-decapeptide – it is made up of a chain of 15 amino acids. One animal study has shown that BPC157 reversed congestive heart failure and various arrhythmias, mainly through an interaction with the nitric oxide system. [R]

PT-141

In two studies, PT 141 induced a statistically significant erectile response in healthy male subjects and Viagra-responsive erectile dysfunction (ED) patients compared to placebo. Based on its erectogenic potential and tolerability profile, PT-141 is a promising candidate for further evaluation as a treatment for ED. [R]

Melanotan 2

Melanotan II was initially developed to prevent skin cancer. In an animal study, abdominal fat pads were 40 percent smaller in animals that received either a low or high dose of Melanotan II compared with those that did not, and it appeared that the effects were independent of caloric restriction. [R]

Oxytocin

Oxytocin is released in response to the activation of sensory nerves during sexual activity, labor, and breastfeeding. It is also released in response to low-intensity stimulation of the skin, e.g., in response to touch, stroking, warm temperature, etc. [R]

Triptorelin

Triptorelin has been proven to act on the pituitary to cause the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), two gonadotropins that act on the male testes to stimulate testosterone production and on the female ovaries to induce synthesis of estrogen. [R]

Growth Hormone Releasing Hormones

Growth hormone-releasing hormone (GHRH) is a peptide with 44 amino acids in its chain. Research has found that GHRH production depends upon age, sex, and metabolic status. Defects in GHRH have been shown to cause abnormal growth. They are available in the following types: [R]

Sermorelin

A short-term clinical study set out to investigate the effect of Sermorelin intravenous injection in short children with pulsatile GH secretion. Sermorelin was found to produce small acute rises in prolactin, follicle-stimulating hormone, and luteinizing hormone. [R]

CJC-1295

In a study performed at two investigational sites, subcutaneous administration of CJC-1295 resulted in sustained, dose-dependent increases in GH and IGF-1 levels in healthy adults. These data support the potential utility of CJC-1295 as a therapeutic agent. [R]

Growth Hormone Releasing Peptides

Growth hormone-releasing peptides (GHRPs) are also proven to have a remarkable effect on stimulating the release of GH. They affect pituitary somatotrophs to stimulate GH release. GHRPs are available in a variety of types, including:

Tesamorelin

HIV patients taking certain medications often develop excess fat around the stomach area. A pooled analysis of two phase-3 studies found that the visceral adipose tissue decreased significantly in Tesamorelin-treated patients. The drug was found to be overall well-tolerated. [R]

Ipamorelin

A rat study was conducted to investigate the effects of Ipamorelin on longitudinal bone growth rate (LGR), body weight, and GH release. Ipamorelin dose-dependently increased LGR from 42 micromm/day in the vehicle group to 44, 50, and 52 micromm/day in the treatment groups. [R]

Hexarelin

The effects of repeated administration of Hexarelin on growth hormone responsivity were measured. Six healthy adult males (ages 25.4 – 34/1 years) were studied. The results showed that Hexarelin is a potent GH secretagogue active after two successive doses. [R]

Insulin-Like Growth factor-1

Insulin-like growth factor-1 (IGF-1) is a hormone similar in molecular structure to insulin. It consists of 70 amino acids in a single chain and is produced primarily by the liver. Various synthetic analogues of IGF-1 have been developed, including:

IGF-1 DES

IGF-1 DES is a truncated form of IGF-1. Research has shown that IGF-1 DES is about 10-fold more potent than IGF-1 at stimulating hypertrophy. Clinical opportunities for this research compound have not yet been evaluated, but could apply in catabolic states. [R]

IGF-1 LR-3

IGF-1 LR-3 is a lengthened analog of IGF-1. Research has shown that it is approximately three times more potent than IGF-1. This research compound also possesses a significantly longer half-life of about 20-30 hours. It also has improved metabolic stability. [R] [R]

Gonadotrophin Hormone-Releasing Hormone

Gonadotrophin hormone-releasing hormone (GnRH) is made by the hypothalamus region of the brain. This hormone causes the pituitary gland in the brain to synthesize and secrete LH and FSH hormones. In males, these hormones stimulate the testicles to make testosterone. [R]

Triptorelin

In a phase 3 study, the Triptorelin 6-month formulation was well tolerated by patients with locally advanced and metastatic prostate cancer. It was able to achieve and maintain castration for the treatment of locally advanced and metastatic prostate cancer. No patient withdrew from the study as a result of an adverse event. [R]

Deslorelin

An article summarized studies investigating the use of Deslorelin implants for the long-term suppression of fertility in male and female cats. Slow-release Deslorelin implants were found to generate effective, safe, and reversible long-term contraception. [R]

Peptides for Sale at Pure Rawz

PureRawz offers the best peptides for research purposes.

All our products are backed by a Certificate of Analysis (CoA) to showcase their purity. We offer a 100% satisfaction guarantee on every product we sell. So you can trust our products to be safe for research, medical, or clinical use.

Our extensive collection of USA peptides makes PureRawz one of the best peptide companies on the market. From BPC-157 to CJC-1295, all of our research chemicals are of premium grade and ideal for meeting your unique needs.

So if you intend to order peptides online, PureRawz has you covered.