Glycoslim (Insulin Mimetic) – Product Information
What are Glycoslim Capsules?
Glycoslim Capsule is a game-changer in the world of health supplements. Designed for research purposes, it packs a powerful punch in enhancing insulin sensitivity and curbing hunger cravings. With key ingredients, the Glycoslim Capsule is a dynamic blend that aims to optimize glucose metabolism. These natural components work in harmony to potentially revolutionize insulin support and overall well-being,Â
The key ingredients in Glycoslim Capsules per serving (4 Capsules) include:
- Chromium 320mcg
- 10:1 Gymnema Leaf Extract (25% Gymnemic Acids) 1020g
- Bitter Melon (10% Bitters)
- Berberine- Cyclodextrin 300mg
- 25:1 Cinnamon Bark Extract (30% Polyphenols) 255mg
- Alpha Lipoic Acid 150mg
- Black Pepper Extract (95% Piperine) 5mg
Please be aware that the packaging of the product you receive might not exactly match the product image displayed on our website. At times, we make changes to the labeling as part of our ongoing improvement process, and on occasions, we may ship directly from our supplier to expedite order fulfillment. However, please rest assured that the product you receive is identical to what is advertised and meets our high standards of quality.
What is Berberine?
Â Berberine (BBR) is colored a gentle yellow, found within the roots, stems, and fruits of plants all around the world. This substance is BBR, a fascinating nitrogenous isoquinoline alkaloid known by its scientific name, 2,3-methylenedioxy-9,10-dimethoxyprotoberberine chloride. While its name may sound intricate, BBR boasts an intriguing history steeped in traditional Chinese medicine and various global cultures. What makes BBR truly captivating is its presence in a wide array of plants, such as Coptis chinensis, Hydrastis canadensis, and Berberis species. They have served both as a source of sustenance and as powerful medicines for centuries. In traditional Chinese medicine, BBR shines as a versatile remedy, showcasing its antimicrobial properties for treating infections and its role in managing gastrointestinal issues. T
As we understand deeper into BBR’s story, it’s important to emphasize that its primary use is for research purposes. While it has shown immense promise in traditional healing practices, BBR’s full potential is still under exploration by modern science. Researchers are uncovering its chemical composition and diverse biological effects, which range from antioxidative properties to potential antidiabetic, antiviral, and neuroprotective benefits. BBR’s past is steeped in ancient wisdom, but its future is an exciting frontier for scientific discovery and innovation.[R]
What is Berberine- Cyclodextrin?
Berberine, with its impressive array of potential health benefits, often faces a challenge when it comes to its bioavailability. This limitation is primarily due to its poor aqueous solubility and the presence of a multidrug efflux pump known as P-glycoprotein (Pgp). However, the introduction of cyclodextrins (CDs) into the equation offers a promising solution to enhance Berberine’s effectiveness.
Cyclodextrins are unique cyclic oligosaccharides with hydrophobic cavities and hydrophilic outer surfaces. These cavities possess a remarkable ability to form inclusion complexes by welcoming other molecules into their hydrophobic embrace. This property has proven invaluable for improving the solubility, chemical stability, and bioavailability of poorly soluble compounds.
How do Berberine- Cyclodextrin work together?
In the case of Berberine, CDs play a crucial role in overcoming its bioavailability challenges. The formation of a Berberine/Î²-CD inclusion complex not only enhances its solubility but also acts as a modulator for the P-glycoprotein (Pgp). This modulation effectively increases the dissolution rate of Berberine in vitro and its absorption in the intestines in vivo. The mechanism behind this improvement involves the inhibition of Berberine-stimulated Pgp ATPase activity, the downregulation of Berberine-upregulated Pgp mRNA expression, and the suppression of Berberine-induced Pgp expression.
How does Berberine- Cyclodextrin work in diabetes?
When it comes to its antidiabetic properties, Berberine can be a game-changer. It influences human metabolism by kickstarting a process called glycolysis, which is like the engine that converts glucose into energy. By doing this, it helps lower blood glucose levels, which is crucial for individuals dealing with diabetes. Additionally, Berberine has the potential to reverse insulin resistance by boosting mitochondrial function. Think of mitochondria as tiny powerhouses within your cells. When they work better, your body becomes more efficient at utilizing glucose, which can be a significant relief for those managing diabetes.[R]
How does Berberine- Cyclodextrin work in obesity
Studies have shown that treatment with Berberine can lead to an increase in the mass and activity of Brown Adipose Tissue (BAT), commonly known as “brown fat.” This brown fat is a special type of fat that plays a crucial role in regulating body temperature and burning calories. When Berberine is introduced, it seems to stimulate the development of BAT by boosting the expression of brown adipogenic genes. This, in turn, enhances BAT’s ability to generate heat and burn energy. The result? A potential reduction in body weight and improved insulin sensitivity, particularly in individuals dealing with issues like non-alcoholic fatty liver disease and mild overweight conditions.[R]
Berberine- Cyclodextrin Investigations:
- Potential treatment for diabetes[R]
- May promote wound healing in diabetic test subjects [R]
- Potential treatment forÂ obesity [R] [R]
- Potential treatment for hypercholesterolemia (decrease cholesterol) [R] [R]
- May aid in lowering the risk of heart disease in postmenopausal women [R]
- Potential anti-diarrhea activity of Berberine by reducing epithelial gut permeability [R]
- PotentialÂ anticancer effects [R]
Berberine- Cyclodextrin Side Effects
Berberine is generally safe with the proper amount and usage. However, like many supplements, there are some potential side effects to be aware of. Commonly reported reactions include diarrhea, constipation, gas, and an upset stomach. [R]
Moreover, it’s worth noting that a study on the chronic administration of Berberine formulations found no evidence of toxicity. This suggests that when administered responsibly and within recommended dosage limits, Berberine-Cyclodextrin appears to have a favorable safety profile. [R]
What is 25:1 Cinnamon Bark Extract (30% Polyphenols)?
Cinnamon, is derived from the evergreen trees Cinnamomum zeylanicum and Cinnamomum cassia. Part of the Lauraceae family, cinnamon is a beloved flavor used daily in cuisines worldwide. It’s not just about taste, though; cinnamon packs a fragrant punch, making it a sought-after ingredient in aromas, perfumes, and medicinal products.
What makes cinnamon intriguing are its natural compounds, including cinnamaldehyde, cinnamic acid, and cinnamate, which give it its unique flavor and fragrance. Beyond its culinary charm, cinnamon offers a treasure trove of potential health benefits. It’s been studied for its antioxidant, anti-inflammatory, and antimicrobial properties, making it a versatile addition to various applications. Researchers have also explored its potential in addressing health challenges, from diabetes to cardiovascular disease and even neurological disorders like Parkinson’s and Alzheimer’s.
Essentially, cinnamon is more than just a spice; it’s a fragrant and versatile natural wonder with a wide array of potential uses and benefits, making it a cherished ingredient both in our kitchens and beyond. [R]Â
How Does 25:1 Cinnamon Bark Extract (30% Polyphenols) Work?
Cinnamon bark extract, particularly from the Cinnamomum cassia variety, holds a remarkable secret when it comes to its beneficial effects. One of its standout properties is its ability to mimic and sensitize the action of insulin, a hormone crucial for regulating blood sugar levels. This means that cinnamon can assist in making our cells more responsive to insulin, thus aiding in better glucose uptake. It achieves this by influencing key proteins involved in insulin signaling pathways and boosting the expression of insulin-sensitive glucose transporters. In simpler terms, cinnamon helps our bodies use insulin more effectively, potentially mitigating insulin resistance, a factor often associated with conditions like diabetes.[R]
25:1 Cinnamon Bark Extract (30% Polyphenols) Research
- Potentially improves glycemic indices in type II diabetes patients [R] [R]
- May aid in controlling insulin resistance in type II diabetic patients [R]
- May aid to protect against ischemic brain damage [R]
- Potentially improves lipid profile. [R][R]
- Type-A procyanidine polyphenols (TAPP) found in cinnamon may help people with asthma. [R]
- May prevent microorganism proliferation [R]
- Possible treatments for neurodegenerative diseases like Parkinson’s disease [R]
25:1 Cinnamon Bark Extract (30% Polyphenols) Safety and Side Effects
Cinnamon typically carries a low risk of side effects. However, common side effects are potential mouth and lip irritation, possibly resulting in sores. It’s worth noting that some may have allergies to cinnamon, which could manifest as redness and irritation if applied to the skin.[R]
What is Alpha Lipoic Acid?
Alpha-lipoic acid, often abbreviated as ALA, is a remarkable natural compound found in our bodies. It plays a vital role in our mitochondria, the energy powerhouses of our cells. ALA is essential for specific enzymes that help our mitochondria process energy from the food we eat.
But ALA is not just a helper in our energy production; it has a host of other interesting properties. It’s considered a potent biological antioxidant, which means it can help protect our cells from oxidative stress and damage. Additionally, ALA has been explored for its potential in detoxification and as a possible treatment for diabetes. Some studies even suggest that it might have benefits for age-related issues affecting the heart, brain, and muscles. Furthermore, ALA has been linked to modulating various inflammatory pathways in our bodies, hinting at its potential as a valuable compound for overall health. While it’s essential to remember that ALA is primarily intended for research purposes, its multifaceted nature continues to intrigue scientists and researchers worldwide.Â [R]
Alpha-lipoic acid’s journey in the world of science and medicine began many years ago, with its first clinical use dating back to 1959 when it was used to treat acute poisoning caused by the Amanita phalloides, also known as the death cap mushroom. This early discovery paved the way for exploring ALA’s potential in various health applications, making it a subject of ongoing research and interest.Â [R]
How Does Alpha Lipoic Acid Work?
Alpha-Lipoic Acid (ALA) operates as a multitasking player in the realm of insulin and glucose metabolism. It appears to have a profound influence on the insulin-signaling pathway, which plays a critical role in regulating blood sugar levels. Studies suggest that ALA can enhance glucose uptake in both insulin-sensitive and insulin-resistant muscle tissues, essentially helping cells utilize glucose more efficiently. This effect extends to whole-body glucose uptake in obese animals, showcasing ALA’s potential in addressing insulin abnormalities and resistance.
Furthermore, ALA’s impact isn’t limited to muscle tissues. It’s been observed that ALA stimulates glucose oxidation without affecting other metabolic pathways. Additionally, ALA may counteract insulin resistance by addressing permanent glutathiolation and activation of molecules associated with insulin resistance. Moreover, ALA’s influence on membrane receptors implicated in glucose metabolism and its ability to redistribute glucose transporters to the cell membrane can contribute to improved glucose uptake and insulin sensitivity. All these mechanisms make ALA a compelling subject of research in the context of diabetes and metabolic health, with the potential to alleviate insulin resistance and improve glucose metabolism in individuals with conditions like type 2 diabetes.[R]
Alpha Lipoic Acid Research
- May overcome severe insulin resistance [R]
- May help reduce cardiovascular diseases[R]
- Potential antioxidant in the brainÂ [R]
- May be useful for protecting brain tissue from lipid peroxidation and the pathophysiological effects it has in Alzheimer’s disease.[R]
Alpha Lipoic Acid Safety and Side EffectsÂ
Alpha Lipoic Acid is generally considered safe for most individuals. Rarely, some individuals may experience side effects, which can include insomnia, fatigue, diarrhea, or skin rash.[R]
Is Chromium safe as part of insulin supplement?
Chromium is generally safe when used as part of an insulin supplement or in dietary supplements, but it’s essential to use it within recommended dosage limits. Chromium plays a role in insulin’s action in the body and may help improve insulin sensitivity and chromium deficiency. However, excessive intake of chromium supplements can lead to adverse effects. [R] Further clinical trials are suggested to understand this as a medication.
What is Insulin?
Insulin is a crucial hormone in the regulation of blood sugar levels. When someone has high blood sugar, it often indicates a problem with insulin. For those with diabetes, insulin injections are a common medication to manage their condition. For some, managing diabetes requires the use of fast-acting insulin injections to quickly lower elevated blood sugar levels. Additionally, some individuals explore natural aids like cinnamon supplements to complement their diabetes management plan. Insulin can act swiftly to lower blood sugar, and various medications can help in this process. It’s important to consult with a doctor for personalized guidance, as high blood sugar can affect not only metabolism but also the immune system.
Is Glycoslim Capsule safe?
In addition to a lack of consistent evidence of direct benefits, the potential long-term effects of using Glycoslim Capsule are also unknown. Purerawz sells Glycoslim Capsule for research purposes only and not as dietary supplements.
Where to Buy Â Glycoslim Capsules Online
PureRawz offers the finest selection for purchasing Glycoslim Capsule online, available in bottles containing 120 capsules. Some also sell with vitamin E, vitamin d, and magnesium oxide,
In order to produce the quality item, we carry the item’s reference materials with every product we sell. Each of our compounds comes with an independent, third-party-issued Certificate of Analysis for identification, purity or concentrated natural extract, and concentration. PureRawz doesn’t sell modified items, we also guarantee that raw materials are safely tested.
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Glycoslim Capsule is an insulin support capsule. It contains a unique blend of natural ingredients known for their potential health benefits, with a focus on enhancing insulin sensitivity and reducing hunger cravings.The key ingredients in Glycoslim Capsule include Chromium, Gymnema Leaf Extract, Bitter Melon, Berberine-Cyclodextrin, Cinnamon Bark Extract, Alpha Lipoic Acid, and Black Pepper Extract. Each of these components contributes to the overall effectiveness of the supplement. Chromium supports insulin sensitivity, helping cells utilize blood glucose more effectively. Gymnema Leaf Extract, Bitter Melon, and Berberine-Cyclodextrin play pivotal roles in managing blood sugar levels and promoting insulin sensitivity, which is crucial for individuals dealing with diabetes or insulin resistance. Cinnamon Bark Extract, with its polyphenols, helps improve glucose uptake by making cells more responsive to insulin. Alpha Lipoic Acid acts as a potent antioxidant and supports glucose metabolism, potentially aiding in diabetes management.
The combination of these ingredients in Glycoslim Capsule is designed to work synergistically, targeting insulin sensitivity and reducing hunger cravings. While the supplement is intended for research purposes, its components offer a promising avenue for exploring their potential health benefits and their collective impact on overall well-being.
This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).
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