Vincamine – Product Details
It is an experimental supplement being studied for its cognitive and neuroprotective properties. This nootropic is said to remove brain fog, which could lead to a more focused and motivated disposition, and might even improve general cognition by increasing cerebral blood flow. The chemical might also increase mental clarity, wakefulness, and the possibility of mood enhancement. [R] [R] [R]
Vincamine for sale usually comes in doses of 1 mg, 5mg, and 10 mg, as used in laboratory-controlled research. Because this product still requires more extensive studies, buy vincamine for the purpose of research. Vincamine for sale is inadvisable for human consumption.
|Vincamine For Sale|
|Molar Mass||354.450 g·mol−1|
|IUPAC Name||methyl (15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate|
What is Vincamine?
It is one of the monoterpenoid indole alkaloids derived from the Madagascar periwinkle.
Periwinkle was used for headache relief in medieval times, but it wasn’t until 1953 that it was identified as the primary component responsible for the plant’s medicinal uses. [R]
It is a peripheral vasodilator that increases blood flow in the brain. It could be beneficial for maintaining cognitive function, improving memory, concentration, and thinking ability in performing activities requiring attention, as well as primary degenerative and vascular dementia. [R] [R]
Possible Applications of Vincamine
Below are the purported health applications of vincamine. However, all of these still require large-scale studies, meaning you should not consider the results conclusive and helpful to treat any illness.
Vincamine may prevent iron oxidative damage
According to research, it may be beneficial in the elderly because it lowers brain iron concentrations and thus prevents oxidative iron damage to neural cells. It has been shown to cross the blood-brain barrier, and its antioxidant scavenging capacity to inactivate hydroxyl free radicals was ranked alongside Vitamin E. [R]
Iron is thought to accumulate in high concentrations in neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and Huntington’s, contributing to oxidative stress and, ultimately, neuronal death. [R]
Vincamine may have anti-apoptotic effects
Based on a particular study, vincamine, a natural alkaloid, mitigated the negative effects of A25-35 in PC12 cells. The chemical extracted from leaves specifically increased cell survival, decreased apoptosis and cytotoxicity and decreased the concentrations/activities of several oxidative stress indicators. [R]
Vincamine may improve cognitive function
In one study, patients who received it intravenously or intramuscularly experienced a significant increase in cerebral metabolism. [R]
Vincamine may lower blood pressure
Both vincamine and ethyl apovincaminate have been shown in animal studies to lower blood pressure while increasing heart rate. [R]
Vincamine may improve blood flow
It has positive neuropharmacological effects, making it an appealing nootropic compound. Significant increases in global cerebral blood flow, performance on a verbal memory test, and a decrease in ischemic regions were observed in patients. [R]
How Does Vincamine Work?
This product has been shown to relax smooth muscle cells within blood vessel walls as a potent vasodilator. This has the effect of widening or dilating the vessels that bring blood to the brain. Which, of course, results in increased blood flow.
Increasing blood flow to the brain improves the supply of nutrients, oxygen, and glucose. As a result, the brain produces more energy and absorbs more essential resources for cellular maintenance.
Another intriguing mechanism of action for this supplement is the activation of the locus coeruleus, a part of the brain stem. This is a region of the brain stem that is involved in physiological responses to panic and stress.
As we get older, the number of these neurons decreases, and they appear to lose effectiveness. It could awaken and reactivate these neurons, helping to offset some of the normal age-related cognitive declines. [R]
Safety and Side Effects
This product is associated with very few side effects. It may occasionally cause stomach or gastrointestinal problems. Nevertheless, it is recommended to seek medical attention if suspected of accidentally taking vincamine and experiencing such adverse reactions.
Frequently Asked Questions
Is vincamine safe?
Since it is considered a research drug, its safety for human consumption cannot be guaranteed. Pure rawz recommends vincamine for research purposes only.
How is vincamine related to vinpocetine?
The alkaloid vincamine is the source of vinpocetine. The former is being investigated as a dietary supplement for its various biological activities, including the alleged impact on acute ischemic stroke and chronic cerebral vascular ischemia.
What is a peripheral vasodilator?
Peripheral vasodilators are medications used to treat conditions that affect blood vessels in the body’s outer (peripheral) regions, such as the arms and legs. They alleviate these conditions’ symptoms by dilating the blood vessels, preventing them from becoming narrower.
Does vincamine help with degenerative and vascular dementia?
Particular research evidence suggests that it can help with a variety of brain disorders in the elderly, including memory loss, vertigo, transient ischemic deficits, and headache.
In a clinical trial involving 152 patients aged 50 to 85, the therapeutic efficacy of vincamine administered at 30 mg for 12 weeks for the treatment of primary degenerative and vascular dementia was demonstrated. [R]
Despite the supposed health benefit, vincamine is not a prescribed drug or treatment for dementia.
How is vincamine commercially available?
It is typically available in capsules and prepared with other ingredients such as stearic acid, microcrystalline cellulose, and magnesium stearate.
Where can you buy vincamine?
PureRawz is the best place to buy vincamine online. You may visit our website to read the reviews of our customers when they buy our vincamine product.
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Each of our research peptides comes with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.
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