AM833

Description

Overview of AM833

AM833, a synthetic peptide, is an investigational long-acting amylin analogue. It is being studied in preclinical research models for metabolic modulation.

In research and preclinical models, it is classified as a long-acting engineered peptide analogue designed to mimic amylin-like signaling. Researchers have observed that the structural modifications of AM833 may improve its stability and duration of action in investigational systems.

Chemical Properties

Pubchem CID	171397054
Molecular Formula	C194H312N54O59S2
Molecular Weight	4409 g/mol
Synonyms	AM833 1415456-99-3 AM833 [INN] RefChem:573322 AO43BIF1U8
Hazards	Not a hazardous substance or mixture
Storage conditions	Sealed storage, away from moisture and light, under nitrogen
Storage	Powder form = -80°C 2 years and -20°C 1 year
CAS	1415456-99-3

Working Mechanism of AM833

In preclinical research models, AM833 is investigated as a long-acting amylin analogue. It may engage amylin-receptor complexes in central signaling regions of experimental systems. 

Researchers have observed that AM833's extended half-life allows for sustained receptor activation in investigational settings.

Research Applications of AM833

AM833 is being researched in different laboratory models for the following research applications. Though long-term studies are required to validate the following applications in research models.

1. Metabolic regulation models

It may be used to study energy-balance modulation in controlled research models.

2. Combination pathway research (dual-modulator models)

The peptide is applied in combination with investigational models (e.g., with incretin-based agents) to explore multi-pathway synergy.

Why Choose Purerawz for AM833?

At Purerawz, every batch of AM833 is handled with strict quality control to ensure reliability for research purposes. However, users should independently verify documentation before research use. 

All materials are packaged according to laboratory safety standards and shipped in compliance with applicable handling regulations.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human usage.

Reference Links

• D’Ascanio, A. M., Mullally, J. A., & Frishman, W. H. (2023). AM833. Cardiology in Review, Publish Ahead of Print. https://doi.org/10.1097/crd.0000000000000513
• ‌(2026). Clinicaltrials.gov. https://clinicaltrials.gov/study/NCT07253285
• Davies, M. J., Bajaj, H. S., Broholm, C., Eliasen, A., Garvey, W. T., Roux, le, Ildiko Lingvay, Lyndgaard, C. B., Rosenstock, J., & Pedersen, S. D. (2025). AM833–Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes. New England Journal of Medicine, 393(7). https://doi.org/10.1056/nejmoa2502082