MOTS-c

Description

What is MOTS-c?

MOTS-c is a peptide that has shown significance in the field of research. It is a 16-amino acid peptide that is encoded in the mitochondria, within the 12S rRNA gene.

Experimental findings indicate that this compound may modulate metabolic pathway activity and influence insulin-associated signaling cascades. A few studies have also suggested that MOTS-c may contribute to the regulation of cellular energy dynamics in controlled in vitro models.

Chemical Properties

Product Name	MOTS-c
CAS Number	1627580-64-6
Molar Mass	2174.7 g/mol
Chemical Structure	C101H152N28O22S2
IUPAC Name	H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH

How does MOTS-c work?

MOTS-c has been observed in experimental models to interact with intracellular signaling networks.

Preclinical investigations indicate that MOTS-c may activate AMP-activated protein kinase (AMPK) signaling cascades in controlled in vitro systems.

Through AMPK pathway engagement, MOTS-c has been shown to influence transcriptional programs. These programs are associated with mitochondrial bioenergetics and substrate utilization.

Potential Research Applications of MOTS-c

1. MOTS-c is investigated in controlled laboratory environments for its effects on AMPK-associated signaling pathways. 
2. MOTS-c can also be studied for its interactions with stress-response pathways and folate-cycle intermediates.

Why Choose Purerawz for MOTS-c?

Purerawz provides MOTS-c with verified purity and quality, suitable for laboratory research. The compounds are handled and stored under conditions that maintain stability for experimental use.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow the IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human usage.

Reference Links

Zheng, Y., Wei, Z., & Wang, T. (2023). MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation. Frontiers in Endocrinology, 14. https://doi.org/10.3389/fendo.2023.1120533
Yi, X., Hu, G., Yang, Y., Li, J., Jin, J., & Chang, B. (2023). Role of MOTS-c in the regulation of bone metabolism. Frontiers in Physiology, 14. https://doi.org/10.3389/fphys.2023.1149120‌
Mohtashami, Z., Singh, M. K., Salimiaghdam, N., Ozgul, M., & Kenney, M. C. (2022). MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases. International Journal of Molecular Sciences, 23(19), 11991. https://doi.org/10.3390/ijms231911991