Thymalfasin

Description

Overview of Thymalfasin

Thymalfasin is a chemically synthesised version of thymosin alpha-1 (Ta1). It is identical to human thymosin alpha-1, an endogenous thymic peptide involved in immune system modulation.

Researchers study lab-made Thymalfasin for its potential ability to modulate immune function in preclinical models.

Chemical Properties

PubChem CID	16130571
Molecular Formula	C129H215N33O55
Chemical Structure Depiction
Synonyms	Thymalfasin 62304-98 Thymosin alpha Thymosin alpha 1 Zadaxin
Molecular Weight	3108.3 g/mol
CAS	69521-94-4
IUPAC	N-acetyl-L-seryl-L-alpha-aspartyl-L-alanyl-L-alanyl-L-valyl-L-alpha-aspartyl-L-threonyl-L-seryl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-threonyl-L-threonyl-L-lysyl-L-alpha-aspartyl-L-leucyl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-lysyl-L-alpha-glutamyl-L-valyl-L-valyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-alpha-glutamyl-L-asparagine

How Does Thymalfasin Work?

In preclinical research models, thymosin alpha-1 (Thymalfasin) has been investigated for its potential interactions with immune signaling pathways, including Toll-like receptors. Observations in laboratory and some clinical studies suggest possible modulation of cytokine production and antigen presentation, though functional effects in humans remain under investigation.

Handling and Storage of Thymalfasin

Handling and storing Thymalfasin is important for long-term research use. Here are the guidelines to follow:

• Researchers have suggested that Thymalfasin powder can be stored at -20°C for 6 months.

• Use it carefully in lab settings.
• Keep vials tightly sealed and clearly labelled with concentration and date of reconstitution.
• Use sterile containers to prevent contamination.
• Keep it away from moisture and humidity.

Research Application of Thymalfasin

Thymalfasin is being researched by various medical analysts in labs for its following potential applications.

• Thymosin alpha-1 has been studied in clinical and preclinical settings for its role in immune modulation in viral infections such as hepatitis B and C.
• Thymalfasin is under investigation in preclinical models for potential effects on antiviral immunity, including exploratory studies related to SARS-CoV-2, but no conclusive clinical evidence exists.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

Reference Links

Dominari, A., Hathaway III, D., Pandav, K., Matos, W., Biswas, S., Reddy, G., Thevuthasan, S., Khan, M. A., Mathew, A., Makkar, S. S., Zaidi, M., Fahem, M. M. M., Beas, R., Castaneda, V., Paul, T., Halpern, J., & Baralt, D. (2020). Thymosin alpha 1: A comprehensive review of the literature. World Journal of Virology, 9(5), 67–78. https://doi.org/10.5501/wjv.v9.i5.67 (2025). Clinicaltrials.gov. https://www.clinicaltrials.gov/study/NCT06821100 Aynekulu Mersha, D. G., Fromme, S. E., van Boven, F., Arteaga-Henríquez, G., Wijkhuijs, A., van der Ent, M., Berghmans, R., Baune, B. T., Drexhage, H. A., & Dalm, V. (2025). Indications for an antidepressive effect of thymosin alpha-1 in a small open-label proof of concept study in common variable immune deficiency patients with depression. Brain, Behavior, & Immunity - Health, 43, 100934. https://doi.org/10.1016/j.bbih.2024.100934