Description

GW-501516 + RAD-140

The PureRawz Cardarine + RAD-140 Formula combines two research chemicals, Cardarine and RAD-140. Cardarine has been researched for its potential to improve metabolism. It may also increase endurance and aid in managing conditions like dyslipidemia and heart disease. RAD-140 is being studied for its ability to promote muscle growth. It also aims to minimize its effects on prostate tissue.

The Cardarine + RAD-140 Formula offers research flexibility in tablets, capsules, and liquid form.

GW-501516 + RAD-140 Formula are available in:

• Tablets: 50 mg per tablet (25 mg RAD-140 and 2 5mg Cardarine) Available in 20 tablets (1000 mg) and 40 tablets (2000 mg)
• Capsules: 50 mg per capsule (25 mg RAD-140 and 25 mg Cardarine) 40 capsules totaling 2000 mg.
• Liquid: 67 mg per ml (33.3 mg Cardarine and 33.3 mg RAD-140), 30 ml, 2000 mg.

Cardarine

CAS	317318-84-6
Molar Mass	471.5 g/mol
Chemical Formula	C21H18F3NO3S2
IUPAC Name	2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid

What is Cardarine?

Cardarine, a synthetic research drug, activates the PPARδ protein and is often referred to as GW-501516. This protein regulates energy synthesis, metabolism, and muscle contraction [R]. Cardarine may have an impact on tissue regeneration and fat metabolism. It might potentially affect muscular and cardiac tissues [R].

Cardarine has been researched to enhance endurance & stamina by increasing fat-burning processes.[R]. It has shown the ability to activate pathways that protect and lessen inflammation in cells involved in myelin formation. This suggests research on disorders like multiple sclerosis may find utility for it [R].

How does Cardarine work?

Cardarine functions through the activation of a protein known as PPARδ. This protein is essential for supporting metabolic processes and maintaining muscular endurance. Studies on mice suggest that PPARδ promotes the use of fatty acids rather than glucose in the synthesis of energy. Exercise usually raises energy through the breakdown of proteins and gluconeogenesis. Cardarine reduces the amount of glucose used by increasing the absorption of fatty acids. Because of this, it is a useful substance to study energy and metabolic processes [R].

Cardarine may:

• It may improve running endurance and fat metabolism in muscles [R]. Thus resulting in a great strength increase.
• It may improve insulin sensitivity, potentially helping in the management of diabetes. [R][R]
• It may lower total and LDL cholesterol, improving lipid levels. This could help in research on dyslipidemia and heart disease risk [R].
• It potentially shows anti-inflammatory activity [R][R]
• It may increase fatty acid oxidation, helping the fat-loss process. This could be useful in research on obesity [R].
• It may have the potential to stimulate weight loss [R]
• It might be useful for the advancement of medical treatments for atherosclerosis. [R]

What is RAD-140?

CAS	1182367-47-0
Molar Mass	393.8 g/mol
Chemical Formula	C20H16ClN5O2
IUPAC Name	2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile

RAD-140 is commonly known as Vosilasarm or Testolone. It is a non-steroidal selective androgen receptor modulator (SARM). It functions as a complete androgen receptor agonist, particularly in skeletal muscle tissue, promoting muscle growth and repair [R][R]. RAD-140 also acts as a partial antagonist in prostate and breast tissues. This inhibits the activation of androgen receptors and cell proliferation [R]. Its targeted mechanism enhances muscle growth while minimally affecting the prostate and seminal vesicles. This is shown by its greater impact on muscle growth than prostate enlargement [R].

This research compound has shown good pharmacokinetics and anabolic potential in rats and primates in toxicological investigations. In preclinical studies, RAD-140 increased muscular anabolism. It had less effect on prostate growth than testosterone [R]. RAD-140 may offer focused anabolic benefits with fewer side effects. Phase I clinical trials are currently being prepared for. These studies look at its potential for treating hormone receptor-positive breast cancer and for cancer cachexia patients [R].

How do RAD-140 sarms work?

RAD-140 is known to interfere with the signaling pathway of estrogen receptors (ER). Direct inhibition or the degradation of ER proteins, results in a decrease in ER activity [R]. Uncertainty surrounds the precise mechanism underlying RAD-140’s tissue-specific actions. Nonetheless, it is believed that some of its activity may come from its capacity to enlist transcription or coregulator components. Another factor might be its lack of aromatization. Furthermore, the effects can be further amplified if 5AR-reduction is absent [R][R].

Research indicates that RAD-140 and its related compound RAD-192 demonstrate neuroprotective properties in cultured neurons. They do so by mimicking the activation of the MAPK/ERK signaling pathway. This mechanism is linked to the protection of non-neural cells by androgen. It is involved in critical brain functions, such as neurogenesis, differentiation, and synaptic plasticity. Memory formation and cell survival are also influenced [R][R]. These findings suggest using RAD-140 as a research chemical to study its effects.

Testolone or RAD140 is being studied for the following potential:

• It may promote muscle hypertrophy or enhance lean muscle mass [R]
• It might have neuroprotective properties that could influence neurodegenerative illnesses like Alzheimer’s [R]
• It potentially shows antitumor activity that may help cancer. [R][R]
• It has the potential to enhance bone mineral density which may aid osteoporosis.[R]

Frequently Asked Questions

Where to Buy the Best Selective Androgen Receptor Modulator Formula?

PureRawz is a well-known supplier of selective androgen receptor modulators, such as the Cardarine + RAD-140 Formula. It is also possible to acquire it separately, which provides the opportunity to investigate these active components, including peroxisome proliferator. Other sarms, including the Ostarine and Ligandrol are also available. These products have additional product descriptions about their potential to impact fat loss, pure muscle growth, and the use of fat for energy. You may also check our main website to check for various sales on popular sarms. All PureRawz products include reference materials to ensure their quality. A Certificate of Analysis from a third-party laboratory is used to verify purity level and identification.

We provide fast free shipping in the United States and worldwide delivery on orders exceeding $100. If you are seeking the best place for your combined formula purchase try us. Payment options for your cart purchase include Bitcoin and PayPal. Shop now for a hassle-free experience! Purerawz provides customer reviews for reliability. To find this section Click on the ‘Reviews’ tab to see what existing customers say about our products. This section may help address any questions, such as typical results others have about SARMs.

Can Cardarine be formulated with Ostarine?

Cardarine may be combined with Ostarine in research studies to investigate potential advantages in endurance, fat loss, and muscle preservation. PureRawz provides a formula called Cardarine + Ostarine + Stenabolic Formula, which includes 30ml of Cardarine, Ostarine, and Stenabolic. This combination is often used in research on synergistic effects on fat metabolism, performance, and recovery.

Disclaimer

This information is for educational use only and does not constitute medical advice as dietary supplements. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with the appropriate IRB oversight. All preclinical research must be conducted with relevant IACUC following the AWA guidelines.

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