Pramiracetam

Description

Pramiracetam Overview

Pramiracetam is a synthetic nootropic from the racetam family, originally developed in the 1970s. Unlike many racetams, it is fat-soluble, a property that influences absorption and cellular distribution in laboratory models. This characteristic also allows it to cross cell membranes more efficiently, making it a valuable tool in studies of memory and learning mechanisms.

Pramiracetam is often described as a highly concentrated racetam, meaning smaller amounts are required to produce measurable effects in laboratory research.

Chemical and Molecular Properties

PubChem CID	51712
Molecular Formula	C14H27N3O2
Molecular Weight	269.38 g/mol
Synonyms	68497-62-1 Pramiracetamum N-[2-[bis(1-methylethyl)amino]ethyl]-2-oxo-1-pyrrolidineacetamide 1-Pyrrolidineacetamide, N-(2-(bis(1-methylethyl)amino)ethyl)-2-oxo- CI-879 FREE BASE
IUPAC	N-[2-[di(propan-2-yl)amino]ethyl]-2-(2-oxopyrrolidin-1-yl)acetamide
CAS	68497-62-1
Labeling	Research Use Only (RUO), not for human or animal consumption.
Chemical Structure Depiction
Purity	99% Purity
Classification	Research Use Only (RUO)
Storage Temperature	Room Temperature below 15°C (59°F)

Mechanisms of Action

The exact mechanism of Pramiracetam is not fully elucidated, but several reproducible effects have been observed in preclinical studies:

• Enhancement of high-affinity choline uptake (HACU)

Research models indicate that Pramiracetam enhances high-affinity choline uptake in the hippocampus. This step regulates acetylcholine production.

• Hippocampal and limbic modulation

Preclinical memory tasks demonstrate that Pramiracetam may reverse experimentally induced amnesia and improve hippocampus-dependent performance.

• Influence on neuronal signaling and local blood flow

Some studies report that Pramiracetam affects nitric oxide synthase signaling and related pathways in brain tissue. This may influence synaptic plasticity and local microcirculation.

Potential Research Applications

Important: The following summaries are provided for research reference only. They do not imply safety, efficacy, or suitability for human use.

• Memory-Related Endpoints: Multiple experimental paradigms, including rodent amnesia models, report improvements in memory performance.
• Reversal of Experimentally Induced Amnesia: In preclinical studies, Pramiracetam has been observed to modulate task performance in laboratory models of experimentally induced amnesia.
• Cognitive Processing in Impaired Models: Certain studies suggest Pramiracetam may enhance attention and cognitive performance in models with prior deficits.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

References:

1. Mauri, M., Sinforiani, E., Reverberi, F., Merlo, P., & Bono, G. (1994). Pramiracetam effects on scopolamine-induced amnesia in healthy volunteers. Archives of Gerontology and Geriatrics, 18(2), 133-139. https://doi.org/10.1016/0167-4943(94)00542-7
2. Systemic administration of pramiracetam increases nitric oxide synthase activity in the cerebral cortex of the rat. (1995, June 1). PubMed. https://pubmed.ncbi.nlm.nih.gov/8557218/