OTR-AC (Ostarine O-Acetate) Product Details
What is OTR-AC?
OTR-AC, also called Ostarine-O-Acetate, is MK-2866 (Ostarine) which has undergone esterification during chemical synthesis to maximize the potency, biodistribution, and half-life. The esterification of anabolic agents results in at least a 10-fold increase in half-life, which means that the active ingredient has the potential to remain bioactive ten times longer. Currently, OTR-AC is being researched to potentially prevent muscle wasting disease and increase muscle mass.
Ostarine is a Selective Androgen Receptor Modulator (SARM). It is also known as enobosarm or Gtx-024. It is a non-steroidal substance that does not undergo aromatization and reduction by aromatase and 5- reductase which is typical of conventional anabolic compounds. [R]
Purerawz sells OTR-AC for RESEARCH PURPOSE ONLY.
|OTR-AC / Ostarine-O-Acetate|
|Molar Mass||431.37 g/mol|
|IUPAC Name||5-(1H-pyrazol-5-yl)-1-[2-[4-(trifluoromethoxy)phenoxy]ethyl]indole-2-carboxylic acid|
How Does OTR-AC Work?
Ostarine binds to androgen receptors, which are body proteins. This may lead to muscles potentially growing when it connects to these receptors.[R]
Selective androgen receptor modulators are a new class of non-steroidal, tissue-specific anabolic agents that have the potential to increase muscle mass and improve physical function without the undesirable side effects on the prostate, skin, or hair that are commonly associated with testosterone or other non-selective, synthetic anabolic steroids. Ostarine is a SARM that, upon binding, may induce conformational changes in the androgen receptor, altering the receptor’s interaction with coactivator and corepressor proteins found in different tissues and changing the receptor’s ability to regulate gene expression. [R]
Numerous animal and human studies have been conducted on the potential application of OTR-AC. Below follows some of the relevant findings:
OTR-AC on Cancer Cachexia
Cancer-induced muscle wasting begins early in a patient’s malignant disease, resulting in decreased physical function and other negative clinical outcomes. The small sample size and diversity of cancer types studied could be viewed as potential limitations, despite the fact that this is the first study to demonstrate that a selective androgen receptor modulator increased lean body mass and improved physical function in cancer patients with pre-existing cachexia (muscle loss). [R]
OTR-AC on Lean Body Mass
In a study conducted on elderly men and postmenopausal women, GTx-024 improved total lean body mass and physical function in a dose-dependent manner and was well tolerated. GTx-024 could be used to prevent and/or treat muscle wasting caused by cancer and other chronic diseases.[R] Additional study is needed to demonstrate its efficacy.
OTR-AC on Postmenopausal Osteoporosis
In ovariectomized rats, Ostarine appeared to have a positive effect on early bone healing. Given its favorable effect on non-osteotomized bone and muscle, this treatment could be investigated further as an osteoporosis therapy. However, potential metabolic side effects should be considered first.[R]
In another study, Ostarine’s short-term therapy of osteoporotic bone improves a number of microstructural bone parameters. Even though biomechanics have not changed, it is possible that a lengthier course of treatment could enhance biomechanical qualities. [R]
Ostarine’s longer-term effects and side effects in osteoporosis require further studies in rat models to eventually understand its safety for human consumption.
OTR-AC on Improvement of Muscle Tissue
Ostarine is a compound that has recently gained popularity as a result of its potential health benefits. It’s a selective androgen receptor modulator (SARM) that has been studied in laboratory research for its ability to improve physical performance and muscle growth. A rat study was done in Sprague-Dawley rats and was able to conclude that Ostarine increased muscle vascularization by increasing capillary density and increasing muscle enzyme activity while having no hypertrophic effect on muscle fibers. [R]
In another study, rats with increased myogenin, MyoD, and MyH expression after receiving Ostarine for 30 days also have more muscle mass. The investigation leads to the conclusion that Ostarine activates the androgen receptor to promote the proliferation and differentiation of muscle tissue.[R]
More research is needed for higher dosages because they can cause unfavorable side effects and may limit their application at these dosages.
OTR-AC on Diabetes
Subjects treated with Ostarine had shown a decrease in fasting blood glucose, a decrease in insulin levels, and a decrease in insulin resistance (homeostasis model assessment), implying that SARMs may have therapeutic potential in diabetics or people at risk for diabetes. [R]
To better comprehend its mechanical function and value, more research is necessary
OTR-AC on Cholesterol
In the same study, OstarineTM caused a dose-dependent decrease in LDL and HDL cholesterol levels, with the average LDL/HDL ratio remaining in the low cardiovascular risk category for all doses. [R] Since there are few studies available, more research is required to demonstrate its effectiveness.
OTR-AC Research may Stack well with:
The AC MK 2866 ester is frequently researched alongside these compounds due to the potential chemical synthesis they have together, though more research is required.
OTR-AC Effects [R]
- Potential to aid the prevention of muscle wasting
- Potential to improve lean body mass
- Potential applications in insulin resistance
- Potential to reduce liver damage
Where to Buy Ostarine Online
PureRawz is a great company to buy OTR-AC for sale. Available in OTR AC Liquid, OTR AC Powder, and OTR AC Tablet.
In order to be the best SARMs supplier, we provide reference materials with every product we sell. Each of our SARMS comes with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.
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Is OTR-AC Illegal to Purchase?
OTR-AC is legal to purchase as a research compound.
Like other selective androgen receptor modulators, it can be used for laboratory research use only. However, since it is on the World Anti-Doping Agency’s list, athletes and professionals should avoid this compound.
OTR-AC has demonstrated its ability to improve lean muscle mass, reduce body fat and increase bone mineral density in a clinical study. More long-term randomized clinical trials are needed to understand its safety and efficacy in humans.