N-Acetyl Semax Amidate + N-Acetyl Selank Amidate Blend

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Description

N-Acetyl Semax Amidate + N-Acetyl Selank Amidate Blend – Product Information

  • N-Acetyl Semax Amidate + N-Acetyl Selank Amidate Blend contains 30mg N-Acetyl Semax Amidate and 30mg N-Acetyl Selank Amidate, totaling 60mg.

What is N-Acetyl Semax Amidate?

N-Acetyl Semax Amidate, or N-Acetyl Semax or Semax, is a synthetic peptide that originates from the naturally existing neuropeptide named ACTH (Adrenocorticotropic hormone). This compound is an adapted form of the initial Semax peptide, engineered by introducing both an Acetyl group and an Amidate group. These additions serve to improve its durability.

Semax has an extra segment called Pro-Gly-Pro (PGP) to make sure it doesn’t break down easily. This unique combination of components makes Semax effective in various ways. One of its key potential benefits is promoting the survival of neurons, which are the building blocks of the nervous system. It’s studied for its potential to be particularly helpful in situations where there’s not enough oxygen reaching the brain, a condition known as hypoxia. Semax also potentially protects against the harmful effects of glutamate, a chemical that can damage brain cells when present in excess.

In the context of research, it is advisable to opt for bacteriostatic water when reconstituting substances rather than sterile water.

N-Acetyl Semax Amidate
CAS Number 80714-61-0
Molar Mass 854.97 g·mol−1
Chemical Formula C39H54N10O10S
IUPAC Name 3-Chloro-2,4-difluorobenzoic acid.

How does N-Acetyl Semax Amidate Work?

Semax operates through a complex mechanism that has been identified through time-dependent analysis of transcriptomic data during cerebral ischemia. Research suggests several key processes that Semax potentially influences: [R]

Regulation of Chemokine Gene Expression: Semax has the potential to affect the genes responsible for producing chemokines, which are signaling molecules that guide immune cells to specific areas. This suggests that Semax might play a role in regulating the immune response in the brain after ischemia.

Transcriptional Activation of the CCR5 Signaling Pathway: CCR5 is a receptor involved in immune cell responses. Semax has the potential. to activate the genes in the CCR5 signaling pathway, which could influence immune cell behavior and potentially contribute to brain protection.

Strengthening of Type I IFN Protective Signaling: Type I interferons (IFNs) are molecules released in response to infections and play a role in the immune response. Semax enhances the genes associated with type I IFN protective signaling, indicating that it might potentially bolster the brain’s defense mechanisms.

Regulation of Ig Synthesis: Semax affects the synthesis of immunoglobulins (Ig), which are antibodies produced by immune cells. This modulation of Ig synthesis could be linked to immune system regulation after cerebral ischemia.

Increase of Igh-1a Expression: The expression of Igh-1a, a specific gene, is potentially significantly increased by Semax. This gene might be involved in critical cellular processes related to brain protection.

N-Acetyl Semax Amidate Research Investigations

  • Can be potentially studied for acute therapy stroke  after cerebral ischemia [R][R]
  • May help cognitive performance studies: neuroprotective and anamnestic effect [R]
  • May help activate Dopaminergic and Serotoninergic Brain Systems [R]
  • Potential beneficial action towards work efficiency [R]
  • Potential treatment for depression and generalized anxiety disorder [R]
  • May help prevent chronic stress in rodent studies [R]

N-Acetyl Semax Amidate Safety and Side Effects

N-Acetyl Semax Amidate has several possible side effects shown in research studies including headaches, nausea, vomiting, and drowsiness.

What is N-Acetyl Selank?

The latest Selank, N-acetyl Selank amidate, has better properties. This modified version has better potential to enter the brain of subjects, making it potentially more effective as a research chemical. This N-acetyl Selank Amidate peptide is more potent, has higher bioavailability, and is more stable, enhancing its potential as a cognitive enhancer in research.

Selank, a preparation developed in Russia, is derived from a natural regulatory peptide called tuftsin. Unlike common benzodiazepine tranquilizers used in alcoholism treatment, Selank has distinct anxiolytic (anxiety-reducing) and nootropic (cognitive-enhancing) properties. It has shown positive effects in patients with uncomplicated anxiety and anxiety-asthenic disorders.[R]

N-Acetyl-Selank Amidate
CAS Number 129954-34-3
Molar Mass 751.9g.mol-1
Chemical Formula C33H57N11O9
IUPAC Name (2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid

How N-Acetyl Selank Work?

The mechanism of Selank involves several actions. It has the potential to regulate the expression of the BDNF gene in the hippocampus, a region of the brain associated with memory and emotions. This gene encodes Brain-Derived Neurotrophic Factor, a protein crucial for promoting the growth, maintenance, and survival of neurons.[R]

N-Acetyl Selank Investigations

  • May aid in coagulation blood clotting research [R]
  • May influence cognitive stimulating effect research [R]
  • Potential treatment for anxiety and depressive disorder research [R][R] 
  • May mediate immune response research [R]

N-Acetyl Selank Safety and Side Effects

The primary side effects frequently associated with Selank in research subjects consist of anxiety, headaches, nausea, dizziness, and fatigue.

FAQs

Are N-Acetyl Semax Amidate + N-Acetyl Selank Amidate capsules safe?

Purerawz sells these capsules for research purposes as a research chemical only not as dietary supplements or immune support supplements. The data presented rely solely on scientific studies that are for reference purposes only.

Where to Buy N-Acetyl Semax Amidate + N-Acetyl Selank Amidate peptide for Sale capsule  Online?

PureRawz is one of the top suppliers of N-Acetyl Semax Amidate + N-Acetyl Selank Amidate for Sale capsule in 60 capsules. We also offer acetyl selank amidate spray as research chemicals.

In order to produce the quality item, we carry item’s reference materials with every product we sell. Each of our compounds sold comes with an independent, third-party-issued Certificate of Analysis for identification, purity or concentrated natural extract, and concentration. PureRawz store chemicals in temperature controlled packaging lasts up to its expiry.

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Conclusion

The combination of N-acetyl semax Amidate and N-acetyl selank Amidate aims to improve the cognition of both peptides. These peptides are researched for their potential to enhance cognitive function and neuroprotection (protect neurons).

N-acetyl Semax Amidate is a synthetic peptide derived from the natural neuropeptide ACTH. It is an enhanced form of the original Semax peptide with the addition of acetyl and amidate groups, which improve its stability and bioavailability. Semax has potential neuroprotective properties and benefits, including promoting neuron survival, protecting against glutamate-induced damage, and potentially aiding in brain oxygenation. It influences gene expression related to immune response, strengthens protective signaling, and affects immunoglobulin synthesis. Research suggests it could be beneficial for stroke therapy, neuroprotection, activating brain systems, improving work efficiency, treating depression, and preventing chronic stress.

N-Acetyl Selank Amidate is a modified version of the Selank peptide, which is derived from the natural regulatory peptide tuftsin. This modified version has improved potential properties for brain penetration and effectiveness. Selank has anxiolytic and nootropic properties, showing positive effects on anxiety and cognitive function. It potentially regulates the BDNF gene in the hippocampus, enhancing neuron growth and survival. It has potential for anxiety management, may influence blood clotting, and could impact cognitive function.

Both peptides aim to improve brain health, potentially creating a synergistic impact on blood-brain barrier cognitive enhancement and neuroprotection in the central nervous system. Even though research shows that peptides might be helpful, it’s important to remember that potential benefits and side effects should be carefully studied and understood. It’s also important to remember that the information given is for research only.

Disclaimer

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).

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