HGH Fragment 176-191

(11 customer reviews)


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HGH Fragment 176-191 – Product Information

Human growth hormone (HGH) fragment 176-191 is synthesized from the C-terminus of HGH. In mice, long-term administration of HGH 176-191 induced weight loss and increased lipolytic (fat-burning) sensitivity. HGH 176-191 is thus known as the “lipolytic fragment” of HGH. [R]

HGH 176-191 has also been shown to decrease body weight. Furthermore, a mice study demonstrated that this synthetic HGH fragment increases blood glucose levels. HGH 176-191 has also helped promote cartilage healing in animal studies. [R][R]

In the context of research, it is advisable to opt for bacteriostatic water when reconstituting substances rather than sterile water.

HGH Fragment 176-191
CAS Number 97305-48-1
Molar Mass 848.9 g/mol
Chemical Formula C39H60N8O13
IUPAC Name (2S)-6-amino-2-[[(2S)-1-[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbonyl]amino]hexanoic acid

What is HGH Fragment 176-191?

HGH 176-191 is a synthetic analog of human growth hormone. It is a synthetic peptide with 16 amino acids in its chain. HGH 176-191 is sometimes referred to as the “lipolytic fragment” of HGH. This is because of research showing that it could potentially induce fat loss in animals. [R]

In animal studies, HGH 176-191 has shown potential as an anti-obesity agent. More promisingly, a cell-based study has demonstrated that this modified form of HGH enhances the anti-cancer potency of compounds targeting breast cancer cells. [R]

HGH Fragment 176-191 Vs HGH

Although HGH 176-191 is derived from the C-terminal sequence of human GH, there are several differences between the unmodified growth hormone and its fragment.

HGH 176-191, for instance, doesn’t induce diabetes. Neither does this HGH fragment increase IGF-1 levels. Higher than normal levels of IGF-1 may cause gigantism in children or acromegaly in adults. Gigantism and acromegaly are consequences of having too much HGH. [R][R]

Additionally, studies showed that GH treatment of both healthy and GH-deficient subjects decreases whole-body carbohydrate oxidation. However, research has indicated that HGH 176-191 doesn’t influence carbohydrate metabolism in the body. [R][R]

HGH Fragment 176-191 Research

Various animal and cell-based studies have been conducted on HGH Fragment 176-191. These studies have shown that the synthetic peptide may have the ability to induce lipolytic action, inhibits lipogenesis, and enhances the toxicity of compounds targeting cancer particles in the breast cancer line.

HGH Fragment 176-191 has also been shown to produce a short-lived rise in blood glucose and a more sustained rise in plasma insulin in mice. Aside from that, this research chemical has demonstrated potential weight reduction and fat reduction effects.

HGH 176-191 and Fat Loss

Results from an animal study show that 14-day administration of HGH Fragment 176-191 reduced body weight and body fat in obese mice. Researchers conducting the study noted that this synthetic peptide induced fat loss by increasing energy expenditure and fat oxidation. [R]

In another study, daily treatment with an oral dose of HGH 176-191 increased lipolytic activity in the adipose tissues of the treated mice. Furthermore, HGH 176-191 treatment showed no adverse effect on the animals’ insulin sensitivity. [R]

HGH 176-191 and Obesity

An animal study has found that daily treatment with an oral dose of HGH 176-191 reduced over 50% of the body weight gain of the animals in comparison with the control. The results demonstrate that this synthetic peptide has the potential to be a safe therapeutic agent for obesity. [R]

In another mouse study, chronic treatment with HGH or its HGH 176-191 increased obese fat cell oxidation and weight loss. Unlike HGH, this fragment didn’t induce hyperglycemia. Nor did it reduce insulin secretion or competed for the HGH receptors. [R]

HGH 176-191 and Breast Cancer

A cell-based study has demonstrated that HGH Fragment 176-191 enhances the toxicity of compounds targeting cancer cells in the breast cancer line. Chitosan nanoparticles loaded with HGH 176-191 demonstrated potential enhanced cytotoxic efficacy against breast cancer cells. [R]

Moreover, the inclusion of HGH 176-191 may promote the inclusion of nanoparticles in tumors while reducing non-target tissue exposure. This, in turn, may enhance therapeutic efficiency and reduce the adverse effects of this anti-cancer compound.

HGH 176-191 and Osteoarthritis

A 2016 study found that hyaluronic acid administration loaded with HGH 176-191 was more effective than either HA or this HGH frag administration alone in a rabbit osteoarthritis model. It was also found that intra-articular HGH Fragment 176-191 administration enhanced cartilage regeneration.

Furthermore, it was noted that osteoarthritic rabbits administered HGH 176-191 injections had less morphological and histopathological damage than the control group. [R]

Where to Buy HGH 176-191 Online?

PureRawz is the best place to buy HGH Fragment 176-191 for sale.

In order to be the best research chemicals supplier, we provide reference material with every product we sell. Each of our products comes with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.

We offer free international shipping on all orders above $100. You can pay for your purchase through various methods, including PayPal and Bitcoin. Click on the ‘Reviews’ tab to check out what existing customers say about our products and great customer service.


HGH Fragment 176-191 has demonstrated the potential ability to decrease fat accumulation by enhancing lipid breakdown and fat metabolism in mice. This synthetic HGH fragment may also potentially induce weight loss, increase the efficacy of anti-cancer compounds and enhance cartilage regeneration.

PureRawz sells HGH 176-191 for research purposes only.


This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).
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11 reviews for HGH Fragment 176-191

  1. User Avatar: Jesse Antonie

    Jesse Antonie

    Very good for the price you are selling. I have just found my new number one supplement store

  2. Anonymous

    I love how this product doesn’t make me jittery and how fast it breaks down fat.

  3. William

    I had a hard time finding this on the market, you guys are trustworthy and very convenient.

  4. Anonymous

    I’m on my 3rd cycle and, along with regular exercise, I’ve lost 20 pounds. Definition is noticeable.

  5. Daniel J. Moreland

    Tried it and had good results, lower back fat decreased.

  6. Christopher

    Perfect for my research needs.

  7. D Campbell

    I wanted to get rid of belly fat, and this product helped. I did not experience any negative side effects. Will continue to use this HGH.

  8. Duncan Norris

    Absolutely loving the gains.

  9. D Hamill

    Faster healing for me after an injury. It works!

  10. Craig Shaw

    Getting some serious results, with my body fat melting away like never before and I haven’t noticed any crazy side effects or jitters. It’s good for focus and clarity too, making sticking to my diet and workouts a breeze.

  11. Randall Simmons (verified owner)

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