Buy Arimistane + Enclomiphene For Sale – Product Details
- Gonads tablets are offered as 50mg Arimistane + 20mg Enclomiphene per tablet.
- Gonads liquid are offered as 16,5mg Arimistane + 16.5mg Enclomiphene per liquid vial.
Arimistane is an aromatase inhibitor which implies a reduction in the production of estrogen. Aromatase inactivators, are bound to the catalytic site, where they are transformed into electrophilic intermediates that become irreversibly attached to the enzyme, blocking its activity. These inhibitors have distinct advantages in compound design because they are highly enzyme specific, produce prolonged inhibition, and exhibit minimal toxicities. Studies show that Arimistane as an aromatase inhibitor effectively delay epiphysial maturation in young subjects and improve testosterone levels in adult subjects by supressing production of estrogen.
Enclomiphene is an estrogen receptor (ER) modulator. It acts as an ER antagonist in humans, sheep, and rabbits and an ER agonist in rats. Enclomiphene inhibits binding of 17beta-estradiol in isolated rabbit uterus. It decreases E2-induced inhibition of follicle stimulating hormone (FSH) secretion in primary sheep pituitary cells in a concentration-dependent manner. Enclomiphene (0.25 and 0.5 mg/animal) inhibits spermatogenesis and decreases serum luteinizing hormone (LH) and testosterone levels in intact or castrated rats. Formulations containing enclomiphene have been used in the treatment of ovarian dysfunction. Enclomiphene is being studied for its potential to increase serum total testosterone levels while maintaining sperm counts in the normal range in men with secondary hypogonadism.
|IUPAC Name||2-[4-[(E)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid|
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