Jackhammer Tablets (Mirodenafil + Amino Tadalafil + SR-9011)

Description

What is Jackhammer (Mirodenafil + Amino Tadalafil + SR-9011) blend?

PureRawz Jackhammer Tablets are composed of SR-9011, Amino Tadalafil, and Mirodenafil. Mirodenafil is a selective and potent inhibitor of phosphodiesterase type 5 (PDE5). It has been investigated for its capacity to sustain elevated cGMP levels. This may promote tissue blood flow and calm muscle relaxation. Amino Tadalafil is another PDE5 inhibitor. It is noted for its extended half-life and ability to support cGMP signaling. This may enhance responses related to vasodilation and cognitive functions. Another part of the blend is the SR-9011, which is a REV-ERB agonist. It has the potential to control circadian cycles, metabolism, and energy expenditure. This may help improve metabolic health and speed up weight loss.

Our tablet has 30 mg of SR-9011, 15 mg of Amino-Tadalafil, and 5 mg of Mirodenafil. Each of the 24 Jackhammer Tablets has 50 mg of active compounds, for a total of 1200 mg.

Researchers studying ED, weight, and sleep disorders may benefit from this blend. This may give a better understanding of clinical efficacy in men with ED and associated health problems. Since ED often occurs alongside other health issues that need further complicated treatments.

What is Mirodenafil?

CAS number	862189-95-5
Molar Mass	531 g/mol
Chemical Formula	C26H37N5O5S
IUPAC Name	5-ethyl-2-[5-[4-(2-hydroxyethyl)piperazin-1-yl]sulfonyl-2-propoxyphenyl]-7-propyl-3H-pyrrolo[3,2-d]pyrimidin-4-one

Mirodenafil or SK3530, is a potent and selective inhibitor of cGMP-specific PDE5. It was developed by SK Chemicals to block PDE5. An enzyme known as PDE5 affects the concentrations of cGMP. This molecule is necessary for a few bodily processes. Comparable substances like sildenafil are less potent and less selective than mirodenafil. Its structure is a little bit different and includes a dihydropyrrole ring. Mirodenafil works well in PDE5 inhibition research due to its unique structure. [R].

Mirodenafil, avanafil, & udenafil are part of a new generation of phosphodiesterase 5 inhibitors. This is due to their enhanced efficacy and reduced adverse effects [R].

How does Mirodenafil work in erectile dysfunction?

A drug called Mirodenafil may help patients with spinal cord injuries (SCI) with ED. SCI has the ability to prevent the release of nitric oxide (NO), which starts an erection. The way that mirodenafil functions is by blocking the PDE5 enzyme. Cyclic guanosine monophosphate is generally broken down by PDE5. (cGMP). cGMP levels remain elevated by halting this disintegration. As a result, the smooth muscles in the penile tissues relax. The development of an erection depends on increased blood flow to the corpus cavernosum. [R].

Mirodenafil may boost NO by relaxing smooth muscles without external stimuli. When combined with a NO donor, the efficacy of Mirodenafil is significantly increased. This amplifies the NO-cGMP signaling pathway. This suggests that mirodenafil may enhance natural processes involved in arousal responses. It potentially potentiates the effects of NO [R]. These findings imply that mirodenafil may be particularly effective in promoting erectile responses.

Mirodenafil potential:

– It may potentially lead to a boost in successful sexual intercourse attempts [R]

– It may potentially treat test subjects with lower urinary tract symptoms (LUTS) [R][R]

– It may also aid ED with Benign prostatic hyperplasia (BPH) [R][R]

– It may potentially help test subjects with erectile dysfunction [R][R][R]

– It may be utilized to test subjects with ED under an antihypertensive drug without adverse effects [R]

– It may potentially help treatment of premature ejaculation [R]

What is Amino Tadalafil?

CAS	145177-42-0
Molecular weight	390.39 g/mol
Chemical Formula	C21H18N4O4
IUPAC Name	(2R,8R)-6-amino-2-(1,3-benzodioxol-5-yl)-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione

Tadalafil is a member of the PDE5 inhibitor family, which also includes drugs such as sildenafil and vardenafil. Tetrahydro-β-carboline, its distinct chemical structure, is what distinguishes it. Favorable pharmacokinetic characteristics of tadalafil include a longer half-life [R]. Tadalafil’s discovery has prompted research in biologically active analogs. Due to its uniqueness, studies are progressing.

How does Amino Tadalafil work?

Tadalafil influences cell cGMP levels. This process commences with the emission of NO, which initiates the production of cGMP. CGMP relaxes smooth muscles and dilates arteries. On the other hand, the degradation of cGMP is caused by PDE5. Tadalafil inhibits PDE5, allowing high cGMP levels. Erectile tissues need this accumulation to increase blood flow [R].

Tadalafil increases central nervous system cGMP signaling, affecting neuronal transmission. PDE5 is highly expressed in the hippocampal and cortical areas of the brain. It has a role in controlling cognitive processes as well as neurotransmitter secretion. Research has been done on tadalafil in models of Alzheimer’s disease. These studies look at the benefits they have for cognition and memory. Preventing cGMP breakdown supports neuroplasticity and neuroprotection [R].

Amino Tadalafil is being studied for the following potential treatment :

– Potential remedy for symptoms of pulmonary arterial hypertension (PAH) and improve exercise capacity [R][R][R][R]

– Tadalafil may potentially treat ED[R][R]

– It may treat BPH in test subjects [R] [R]

– It has the potential to be the sole medication that may simultaneously cure ED and LUTS [R]

– It could potentially boost abdominal lean mass [R]

– It may also aid in fat loss [R]

– It may potentially help ED patients with depressive symptoms [R]

– It is potentially effective in the treatment of Raynaud’s phenomenon. Commonly associated with systemic sclerosis, an autoimmune disease [R]

– PDEs may treat cancer by inhibiting tumor growth.[R]

What is SR-9011?

SR-9011
CAS	1379686-29-9
Molar Mass	479.0 g/mol
Chemical Formula	C23H31ClN4O3S
IUPAC Name	3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide

The effects of SR-9011 on metabolism and energy expenditure are being investigated. As a REV-ERB agonist, it is well known for its capacity to modify circadian rhythms. This modulation is thought to increase energy expenditure and reduce fat mass. These effects may potentially make SR-9011 useful in research on metabolic disorders. Animal studies have shown that SR-9011 may also enhance exercise capacity [R].

How does SR-9011 work?

SR-9011 targets various types of nuclear receptors, including receptor-ERB. The body’s regular cycles and metabolism are regulated by these receptors, which aid in controlling key genes. SR-9011 supports metabolic processes and helps adjust to daily fluctuations. Fatty acid burning may increase while fat synthesis decreases. These effects may improve metabolic health and endurance. Also, SR-9011 reduces pro-inflammatory chemical production, reducing inflammation. Heart health and central nervous system stimulation are unaffected by this chemical [R][R].

SR-9011 potential benefits:

– It may have potential anti-aging properties [R]

– It may help in circadian rhythm or sleep disorders [R]

– It may potentially aid in fat loss [R].

– It may potentially aid in treating Alzheimer’s disease[R][R]

– It may aid in potentially treating cancer [R]

Frequently Asked Questions

If Sildenafil doesn’t work in my studies, what are the best alternative PDE5 inhibitors?

In the past, Sildenafil (Viagra) was known for its adverse side effects & eventual inefficacy after prolonged use. Researchers are increasingly interested in novel PDE5 inhibitors for ED and other disorders. The Jackhammer Tablets contain new PDE5 inhibitors such as Mirodenafil & Amino Tadalafil. Together with SR-9011, this product offers additional benefits for research purposes.

It is important to note that PureRawz sells these tablets exclusively for research only. It is NOT sold as dietary supplements or medicine for ED. Further research/ clinical trials are required to understand the safety and efficacy of the compounds.

Where to Buy the Best Mirodenafil + Amino Tadalafil + SR-9011 ?

PureRawz is a leading source to purchase potent formulation for erectile dysfunction compounds. We get our raw ingredients from high-quality sources. Our chemicals have independent, third-party Certificates of Analysis for purity identification. Our product page also contains product information that can be useful for additional information for your research. If your research is looking for affordable alternatives and individual profound effects? You may opt to consider Mirodenafil and Amino Tada tabs or a blend of Mirodenafil + Amino Tadalafil. It is also well known that PureRawz offers other synthetic compounds. This comprises selective androgen receptor modulators (SARMs) available in multiple variants.

We offer free shipping on orders over $100 in the US and abroad! This makes us the top options for the best Mirodenafil + Amino Tadalafil + SR-9011 blend near you. We also offer fast shipping. Payment can be made by PayPal or Bitcoin. Click customer reviews or customer ratings to read what people think about our products and great prices

Disclaimer

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with the appropriate IRB oversight. All preclinical research must be conducted with IACUC following the AWA guidelines.

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