Description
What is L-Carnitine?
L-carnitine is a quaternary ammonium compound involved in mitochondrial fatty-acid transport mechanisms.
Researchers study L-Carnitine in laboratory models to understand its potential role in facilitating the translocation of long-chain fatty acyl groups across the inner mitochondrial membrane. This process occurs through the carnitine shuttle system.
The mechanism enables β-oxidation reactions within the mitochondrial matrix in research preclinical models.
Chemical Properties
| Property | Value |
| Compound Name | L-Carnitine |
| IUPAC Name | (R)-3-Hydroxy-4-(trimethylazaniumyl)butanoate |
| CAS Number | 541-15-1 |
| Molecular Formula | C7H15NO3 |
| Molecular Weight | 161.20 g/mol |
| Chemical Classification | Quaternary ammonium compound |
| Structural Features | Hydroxyl group, carboxylate group, trimethylammonium moiety |
| Chirality | L-isomer (biologically relevant stereoisomer) |
Mechanism of Action of L-Carnitine
In different research models, L-carnitine appears to work by facilitating the entry of long-chain fatty acids into the mitochondria. Mitochondria are the cell's energy-producing organelles, which researchers study in preclinical models.
Disclaimer
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Reference Links
National Institutes of Health. (2017). Office of Dietary Supplements - Carnitine. Nih.gov. https://ods.od.nih.gov/factsheets/Carnitine-HealthProfessional/
Alhasaniah, A. H. (2023). l-carnitine: Nutrition, pathology, and health benefits. Saudi Journal of Biological Sciences, 30(2), 103555. https://doi.org/10.1016/j.sjbs.2022.103555
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