L-Carnitine

Description

What is L-Carnitine?

L-carnitine is a quaternary ammonium compound involved in mitochondrial fatty-acid transport mechanisms. 

L-Carnitine is an essential component of the carnitine shuttle, which facilitates the translocation of long-chain fatty acyl groups across the inner mitochondrial membrane. Researchers continue to investigate how this established mechanism influences cellular metabolism under different experimental conditions. This transport mechanism enables β-oxidation of long-chain fatty acids within the mitochondrial matrix.

Chemical Properties

Property	Value
Compound Name	L-Carnitine
IUPAC Name	(R)-3-Hydroxy-4-(trimethylazaniumyl)butanoate
CAS Number	541-15-1
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Chemical Classification	Quaternary ammonium compound
Structural Features	Hydroxyl group, carboxylate group, trimethylammonium moiety
Chirality	L-isomer (biologically relevant stereoisomer)

Mechanism of Action of L-Carnitine

L-Carnitine is an essential component of the carnitine shuttle that transports long-chain fatty acyl groups into mitochondria for β-oxidation. Ongoing research investigates how this established transport mechanism influences cellular metabolism and mitochondrial function under various experimental conditions.

Potential Research Applications of L-Carnitine

• Carnitine Shuttle Research

Studied in experimental models involving the carnitine shuttle system and long-chain fatty acyl group translocation across mitochondrial membranes.

• Mitochondrial Transport Mechanism Studies

Investigated in laboratory settings examining carrier-mediated transport processes associated with mitochondrial membrane systems.

• Bioenergetics Research

Examined in studies involving mitochondrial bioenergetic pathways and substrate utilization under controlled conditions.

• Lipid Metabolism Pathway Analysis

Used in research involving fatty acyl-CoA metabolism and related biochemical pathways.

• Metabolic Flux Studies

Investigated in experimental models analyzing metabolic flux and pathway interactions within cellular systems.

• Cellular Metabolism Research

Studied in in vitro systems involving biochemical processes related to cellular metabolic activity.

• Transporter Interaction Studies

Examined in research involving carnitine transporters, substrate affinity, and molecular transport dynamics.

• Comparative Compound Research

Used in structure–activity relationship (SAR) studies involving carnitine analogs and related compounds.

Why Choose L-Carnitine for Purerawz?

Our products are supported by analytical verification processes used to assess compound identity, purity, and batch consistency. Independent third-party testing and batch-specific documentation, including 

Certificates of Analysis (COAs) are available to support quality assessment and product transparency. Materials are handled and stored in accordance with laboratory research requirements. Compound identity, purity, and batch consistency are assessed using validated analytical methods, as documented in batch-specific Certificates of Analysis (COAs). 

Disclaimer

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY.  Our content is intended to be used and must be used for informational purposes only. 

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ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human usage.

Reference Links

• National Institutes of Health. (2017). Office of Dietary Supplements - Carnitine. Nih.gov. https://ods.od.nih.gov/factsheets/Carnitine-HealthProfessional/
• Alhasaniah, A. H. (2023). l-carnitine: Nutrition, pathology, and health benefits. Saudi Journal of Biological Sciences, 30(2), 103555. https://doi.org/10.1016/j.sjbs.2022.103555
• Bremer, J. (1983). Carnitine—Metabolism and Functions. Physiological Reviews, 63(4), 1420–1480. https://doi.org/10.1152/physrev.1983.63.4.1420
• Flanagan, J. L., Simmons, P. A., Vehige, J., Willcox, M. D. P., & Garrett, Q. (2010). Role of carnitine in disease. Nutrition & Metabolism, 7, 30. https://doi.org/10.1186/1743-7075-7-30
• Houten, S. M., Violante, S., Ventura, F. V., & Wanders, R. J. A. (2016). The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders. Annual Review of Physiology, 78, 23–44. 10.1146/annurev-physiol-021115-105045