RAD 140 (Testolone)

(55 customer reviews)

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Description

RAD 140 (Testolone) – Product Information

RAD-140, also known as Testolone, is a non-steroidal selective androgen receptor modulator (SARM). Like other SARMs, it is being studied for its potential to bind to specific androgen receptors and as a result does not cause the full spectrum of androgenic effects as similar substances like anabolic steroids, DHT, or testosterone replacement therapy.

Testolone hasn’t been around for long. In fact, this research compound was developed in 2010 as a potential treatment for osteoporosis. At the time of writing, it is mostly being investigated as a research compound with the potential ability to enhance muscle hypertrophy and promote muscular gains.

Research has shown that the stability of RAD-140 is high in incubations with rats, monkeys, and human microsomes. The research compound has also demonstrated good bioavailability in rats and monkeys as well as an excellent affinity for the androgen receptor in skeletal tissue. [R]

Recent studies investigated the effects of RAD-140 on levator ani muscle weight and prostate weight in castrated rats, which are sensitive markers of anabolic-androgenic action in young nonhuman primates. The final results showed that RAD-140 stimulates the levator ani muscle.

RAD-140
CAS Number 1182367-47-0
Molar Mass 393.83 g/mol
Chemical Formula C20H16ClN5O2
IUPAC Name 2-chloro-4-{[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino}-3-methylbenzonitrile

RAD-140 Research

Multiple animal studies have been conducted on RAD-140. This research compound has also undergone numerous clinical trials or human studies. In this section, we’re going to highlight what research has unearthed so far about this research compound.

However, it must be understood that the Food and Drug Administration (FDA) hasn’t approved RAD-140 for human use. This compound should be used for laboratory research use only and is not intended for human consumption.

 

RAD-140 and Neuroprotection

In a study involving rats, scientists investigated the potential ability of RAD-140 to offer neuroprotection in cultured rat neurons and male rat brains. In cultured hippocampal neurons, RAD-140 was observed to be as effective as testosterone in reducing cell death induced by apoptotic insults.

In experiments with gonadectomized male rats, RAD-140 exhibited neuroprotection of hippocampal neurons against cell death caused by systemic administration of the excitotoxin kainate, highlighting its preclinical efficiency in neuroprotective actions relevant to Alzheimer’s disease. [R]

 

RAD-140 and Muscle Mass

One study investigated the anabolic effects of RAD-140 in young, male cynomolgus monkeys. Researchers examined gross body weight, which we know to be a sensitive marker of anabolic androgen action in young nonhuman primates.

While there was no consistent effect on absolute fat mass, the muscle mass showed a qualitative trend that increased with dosage. It appeared that the majority of muscle mass increase was due to lean mass increase. This shows the immense promise of potential muscular gains brought on by RAD-140.

In short, research suggests that RAD-140 may increase lean muscle. If the RAD 140 dosage is limited, however, these effects will be limited in subjects.

RAD-140 and Breast Cancer

RAD-140 is currently under investigation as a potential treatment for breast cancer.

In a cell study, oral administration of RAD-140 inhibited the growth of AR/ER+ breast cancer via the androgen receptor-mediated suppression of the ESR1 gene, both as a single agent and in combination with palbociclib (prescription medicine for certain types of breast cancer). [R]

Androgen and estrogen-receptor-positive (AR/ER+) is a common form of breast cancer. It is sensitive to hormones, and therefore, medications that affect these receptors, such as SARMs like RAD 140, which are being investigated for their cancer-fighting potential. [R]

 

RAD-140 FAQs

How Does RAD-140 Work?

RAD-140 works by selectively targeting androgen receptors in the muscle and bone tissue, leading to a potential increase in lean muscle mass and a decrease in body fat.

This distinguishes RAD, as well as other SARMs, from anabolic steroids, testosterone, and DHT which do not spare androgen receptors in the reproductive organs.

 

Is RAD-140 Legal?

RAD-140 is legal to buy and sell as a research compound.

However, since this drug is on the World Anti-Doping Agency’s (WADA’s) list, it cannot be used by athletes and professionals. It is also illegal for human consumption.

 

What Is The Half-Life of RAD-140?

There are conflicting reports about the half-life of RAD 140. While some reports put the half-life at 16 hours, other researchers state that the compound has a long half-life of up to 60 hours.

 

Does RAD-140 Cause Testosterone Suppression?

According to a study conducted in 2010, 28 days of dosing with RAD 140 suppressed testosterone levels by approximately 200 – 300 ng/dL, with similar suppression in all three groups, although testosterone levels were significantly different for only the 0.01mg/kg group (p < 0.05). [R]

 

Does RAD-140 Cause Acne in Subjects?

There is no mention of RAD 140 causing acne in this drug’s various animal studies.

 

Is RAD-140 Orally Bioavailable?

In pre-clinical characterization, this research compound had good bioavailability in rats and monkeys. Further research is needed to verify its bioavailability in humans.

 

Where to Buy RAD-140 Online

PureRawz is the best place to buy RAD-140 online. Our RAD-140 cost is lower than any other supplier, whether it’s RAD-140 capsules, liquid, or tablets.

In order to be the best SARMs supplier, we provide reference materials with every product we sell. Each of our SARMS comes with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.

We offer free international shipping on all orders above $100. You can pay for your purchase through various methods like crypto and credit card. Click on the ‘Reviews’ tab to check out what existing customers have to say about our products and great customer service.

 

Summary

RAD-140 has demonstrated anabolic activity on muscle in preclinical studies in rats and monkeys. In pre-clinical characterization, this research compound has demonstrated an excellent affinity for the androgen receptor. RAD also had good bioavailability in rats and monkeys.

Disclaimer
This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).
Our content is intended to be used and must be used for informational purposes only. It is very important to do your own analysis and research from Trusted Sources before making any purchase based on your own personal circumstances. You should independently research and verify any information that you find on our Website and wish to rely upon.
By completing and paying for your order, you agree to our Terms and Conditions. Customer satisfaction is our number one priority, if you are not 100% satisfied with the product you received, please contact us at [email protected]
ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY not for veterinary or human usage.

COA

COA RAD 140 lot 0086 2023 08 18 PR1 page 0001

55 reviews for RAD 140 (Testolone)

  1. User Avatar: Scott Finnegan

    Scott Finnegan

    Best RAD I’ve tried!

  2. Jackson Peters

    Always been my ultimate favourite – gives great results!

  3. Ryan Weber

    Loving it!

  4. Aiden Green

    Super happy with this RAD! … very efficient shipping and great customer service too.

  5. Collin Barlowe

    Super lean gains.

  6. Sam Quinley

    Lean gains noticed very quickly.

  7. Edwil Peterson

    Very good muscle and strength enhancement

  8. Peter Crafford

    Amazing stuff – really helps in the gym and reaching your goals.

  9. Russell L

    Great strength booster. Has been breaking all my previous PR’s and seeing results.

  10. Thomas Mckillan

    Happy with fast fat loss. My first time using your product and its the best!

  11. Maria S

    Easy excess fat loss.

  12. Derek Rosen

    This by far is the highest quality rad140 I’ve used since the first time I’ve tried it. Definite strength and size gain. I’m very impressed. Would recommend this to a researcher looking for a good overall gain in strength.

  13. Joey

    Awesome

  14. Larian

    Another amazing one from Purerawz! Keep up the quality guys!

  15. vasquezjacob203

    This product gives me huge energy benefits, as well as great muscle stimulation and strengthening.

  16. Jamie G

    This is insane. Its really a good combination with Ligandrol (LGD 403). I notice that I am much stronger than before and it really helped me every time I worked out.

  17. G Ryan

    Always a clean product. This and mk-677 are a potent combination.

  18. Caleb K

    Does exactly what it’s intended to!

  19. Devin Plourde

    Seems to be working even though I haven’t started working out yet lol – my arms are definitely more muscular already, and I definitely have gained some strength already.

  20. Liam McWells

    Great stamina and endurance booster.

  21. Russell Moore

    Excellent quality product. It works! I experience great results – I’ve been using it for over a year now. Highly recommended.

  22. Anderson Louw

    I like that I dropped some unwanted fat with my first cycle. My endurance went through the roof! I am very impressed with the quality.

  23. Jbahe12

    Pure Rawz RAD 140 gets me the best results and that’s why I continue to shop here.

  24. Jeffrey Hill

    I use this product to help me with my workouts. I have only been on it for a week and already I can feel the difference in my strength.

  25. Flem93

    Great product. Tablets are well made and worked perfect for research and did everything it should have.

  26. Pieter

    Amazing product, been destroying the gym, would highly recommend

  27. Anonymous

    After using RAD 140 for eight weeks, I was impressed with the physical results. It gave me more energy, definition, strength, and power, and I look pretty jacked. Well recommended!

  28. scarey241 (verified owner)

    Excellent product!!!

  29. Dan Michaels

    Seeing awesome gains from this, very happy with the quality

  30. Dan Michaels

    Seeing awesome gains from this, very happy with the quality.
    This will be my new go to for sure.

  31. Dan Henderson

    This stuff has taken my muscle game to a whole new level. I’m talking serious strength gains and muscle definition like never before. The best part is that there are no crazy side effects like with some other compounds. My workouts are more intense, and my recovery is on point.

  32. James Hunt

    Excellent muscular stimulation and strength. Highly recommended!

  33. Justin M (verified owner)

    Legit product. Has worked extremely well and felt a difference within a few doses. I highly recommend.

  34. Marcus Crook

    My rad arrived today and cannot wait to try it out. Thank you for making this happen

  35. Luka

    New SARMS and this website are my best suppliers in the world. I would buy again soon

  36. h20thebro07

    Free points

  37. Edward Long (verified owner)

    This is amazingly quick and produces great results.

  38. Zac (verified owner)

    Haven’t tried yet

  39. Verified Buyer (verified owner)

    Great company and products.

  40. Bryan K. (verified owner)

  41. Frank P. (verified owner)

  42. MAURICE C. (verified owner)

    Haven’t tried yet.

  43. kirby flynn (verified owner)

    Their rad is over the top compared to any other company I’ve ever tried

  44. brent o. (verified owner)

  45. Richard (verified owner)

    Compliments my weight gain to muscle.

  46. josh

    Excellent product!

  47. k g day (verified owner)

    5+ star products! Very potent and extremely effective. I use this on myself. Not for human consumption I know. But I am responsible for myself. @20mg daily is the sweet spot. Anything more than that is just too much for me and sides start to show. Drink plenty water! And get a joint protection supp.

  48. Anonymous (verified owner)

  49. MAURICE CHERRY (verified owner)

    Seems to be working; muscles full and hard.

  50. Marc Oliveira (verified owner)

    Not even a week in of using this product and I can already see and feel great results. This stuff is legit folks, and in my experience, the best and most potent I have ever used. My order came on time and I will be purchasing exclusively from this company going forward. Highly recommended! Thank you guys!

  51. Zachary Barajas (verified owner)

  52. Anthony (verified owner)

  53. Robert alexander (verified owner)

  54. raymondwick1 (verified owner)

    Love the product. Reminds me a lot of how Tren, or Anavar react in my rat. Great pumps and makes you very vascular. Strength is through the roof. Also take TRT, so keeping those levels up and running a 12 week cycle. Great results so far.

  55. daxojap106

    Seeing gains in strength and muscle mass. Feel like a beast during workouts.

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