Arimistane (Capsules) – Product Details
Arimistane is an aromatase inhibitor that brings about a reduction in the production of estrogen. Studies show that Arimistane as an aromatase inhibitor effectively delays epiphyseal maturation in young subjects and improves testosterone levels in adult subjects by suppressing estrogen production.
Pure Rawz sells Arimistane for research purposes only.
Arimistane | |
CAS Number | 1420-49-1 |
Molar Mass | 284.17g.mol-1 |
Chemical Formula | C19H24O2 |
IUPAC Name | (8R,9S,10R,13S,14S)-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-7,17-dione |
What is Arimistane?
Arimistane or Androsta-3 5-diene-7 17-dione is an aromatase inhibitor. This compound is also an analog of DHEA, an androgenic hormone made by your adrenal glands. Arimistane also exists naturally in the body and was first discovered in human urine in 1971. [R]
Later on, in the early ’90s, Arimistane was synthesized and tested for its ability to inhibit aromatase in human placental microsomes. All the steroids used in the study, including Arimistane, inhibited the enzyme in a competitive manner, with Ki’s ranging from 0.058 to 45 micro mm. [R]
Do Aromatase Inhibitors Increase Testosterone?
Research has shown that lowering estrogen levels, by administering an aromatase inhibitor, causes an increase in luteinizing hormone (LH), follicle-stimulating hormone (FSH), and testosterone. Aromatase inhibitors have thus been suggested as a tool to increase testosterone levels. [R]
Another study was conducted to investigate the effects of aromatase inhibition in elderly men with low or borderline-low serum testosterone levels. The study found that aromatase inhibition increases testosterone levels to the youthful normal range in older men with mild hypogonadism. [R]
Do Aromatase Inhibitors Reverse Gyno?
Multiple case reports indicate that Aromatase inhibitors may be used to treat or prevent gynecomastia or the enlargement of breast tissue in men. Gynecomastia is triggered due to a decrease in the amount of testosterone vis-a-vis aromatase enzyme. [R]
In one study, five boys with pubertal gynecomastia and breast tenderness were treated for 6 months with a specific aromatase inhibitor. Breast size decreased in 4 out of 5 patients, and in 1 of these 5 boys, glandular breast tissue disappeared completely. [R]
How does Arimistane Work?
Arimistane inhibits aromatase to increase testosterone levels in the body. It does that by blocking estradiol, a form of the hormone estrogen. While it is identified with specific sex, both estradiol and testosterone are found in women and men.
Arimistane vs Arimidex
Arimistane and Arimidex are both aromatase inhibitors.
Both work by suppressing the production of estradiol, an enzyme that stimulates the production of estrogen in the body. Both also increase testosterone levels in the body. The duo does that by decreasing the amount of estrogen the body makes.
However, while Arimistane isn’t FDA-approved, Arimidex was FDA approved in 1995. It is used to treat breast hormone receptor-positive receptor early breast cancer in postmenopausal women. Arimidex is typically given as an adjuvant treatment after surgery has been administered.
Arimistane Research
Only one human study has been conducted on Arimistane to date. In the study, urine samples of three healthy volunteers were analyzed after controlled single administration of Arimistane. No relevant effects on the steroid profile could be detected. [R]
Arimistane FAQs
Is Arimistane a prohormone?
Arimistane is not a base prohormone. Prohormones are naturally occurring compounds that convert to anabolic hormones via an enzymatic process. They are sometimes also referred to as “light steroids,” “suicide aromatase inhibitor,” or “weak hormones.”
Can Arimistane increase testosterone?
Health experts claim that Arimistane does increase testosterone levels in the body. In doing that, it becomes similar to aromatase inhibitors like Arimidex and Aromasin. [R]
Is Arimistane legal?
This estrogen blocker is banned by the World Anti-Doping Agency and is yet to be approved by the FDA. Therefore, it is illegal to buy, sell, and use Arimistane as a dietary supplement. However, it is legal to buy and sell Hi-Tech Pharmaceuticals Arimistane for laboratory and research purposes.
Does Arimistane have any side effects?
No studies have been conducted on Arimistane to substantiate its side effects.
Aromatase inhibitors tend to induce joint and muscle pain, loss of sex drive, hot flashes, and night sweats. Randomized clinical trials on select populations need to confirm whether or not Arimistane causes these side effects.
Does Arimistane increase muscle mass?
Studies investigating the potential effect of this anti-estrogen compound on muscle mass are lacking.
The use of aromatase inhibitors is associated with maintenance of total body fat, an increase in lean body mass, and free testosterone in AI users at 24 months. The mechanisms and implications of these changes require further exploration. [R].
Does Arimistane cause reproductive harm or birth defects?
Clinical trials are needed to confirm or repudiate this.
Having said that, aromatase inhibitors have been shown to harm the fetus or cause loss of pregnancy in pregnant patients in an animal study. [R]
Do aromatase inhibitors prevent estrogen rebound?
According to the American Cancer Society, aromatase inhibitors don’t stop the ovaries from making estrogen. They only limit estrogen levels in women whose ovaries aren’t making estrogen (such as postmenopausal women). [R]
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Where to Buy Arimistane Online
Pure Rawz is the best place to buy Hi Tech Arimistane online.
In order to be the best research chemicals supplier, we provide reference materials with every product we sell. Each of our products comes with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.
We offer free shipping on all orders above $100. You can pay for your purchase through various methods, including PayPal and Bitcoin. Click on the ‘Reviews’ tab to check out what existing customers have to say about our products and great customer service.
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