What is Vinpocetine?

Vinpocetine is a synthetic substance similar to a substance found in the periwinkle plant (Vinca minor).

Though evidence for its brain health benefits is mixed, it has the potential to improve cognitive function while also increasing total cerebral blood flow and metabolism.

Although it may benefit most people, Vinpocetine poses risks to specific groups and the long-term effects are unknown. The FDA issued a warning in 2019 to those who are pregnant or may become pregnant to avoid Vinpocetine due to safety concerns. [R]

Thus, Vinpocetine still requires several clinical trials to determine its exact effect on a certain disease or health condition.

Vinpocetine is not approved as a pharmaceutical in the United States and is not even an approved dietary supplement. This research drug should only be purchased for research purposes.

Purported Effectiveness of Vinpocetine

Vinpocetine and Memory Loss

According to the chosen clinical trials, Vinpocetine can potentially provide mental support and may treat short-term memory loss in patients with early dementia or other indications of cerebrovascular illnesses.

In a clinical trial with chosen patients who had impaired blood flow to the brain, Vinpocetine was given intravenously for one week. The substance under lab study was then taken orally for 90 days to treat the symptoms of cognitive decline. They saw a notable improvement in their physical balance, and this could be due to Vinpocetine’s ability to improve cognitive performance. [R]

It is well-established that individuals with cognitive impairment or brain damage have an increased TPSO system, which acts as a sensor of brain injury and microglial activation.

Vinpocetine may inhibit the TSPO system’s action by binding to its receptors, which would prevent cognitive deterioration. [R] [R]

Vinpocetine and Stroke

Aside from promoting brain health, Vinpocetine may also help people who experienced a stroke. The activity of Vinpocetine as a platelet aggregation inhibitor and an activator of erythrocyte deformability lowers blood viscosity, in addition to selectively increasing cerebral blood flow, giving this substance the potential to treat ischemic stroke. [R]

Vinpocetine and Cancer

Vinpocetine, both in vitro and in vivo, inhibits the growth of breast cancer cells. [R]

It enhances the effects of radiation therapy in tumor cells in animal studies. [R]

Preliminary data in nasopharyngeal carcinoma patients with radiation injury suggest that a combination of Vinpocetine and dexamethasone may be more effective for cognitive impairment than dexamethasone alone. [R]

It is still worth mentioning that research on cancer patients, in general, is lacking.

Vinpocetine and Alzheimer’s Disease

Vinpocetine has been studied as a treatment for Alzheimer’s disease and disorders of the nervous and circulatory systems because it may increase blood flow to the brain without modifying circulatory parameters. [R] However, more research is required before it can be recommended.

How does Vinpocetine Work?

Vinpocetine is a synthetic apovincamine ethyl ester derived from an alkaloid found in the plant fiber of a common periwinkle plant. [R]

Vinpocetine inhibits PDE1 activity and improves cerebral blood flow by increasing cGMP and cAMP, increasing mitochondrial function, and improving the brain’s utilization of glucose and oxygen. Vinpocetine improves spatial memory in rats by preventing neuronal damage and modulating cholinergic function favorably. [R]

Reviews about this research compound suggest a dosage of three tablets, but again Vinpocetine should only be intended for research usage. It is not a recommended supplement for human consumption.

Commercially produced Vinpocetine usually comes as gluten-free and consists of magnesium stearate along with other ingredients, including stearic acid and microcrystalline cellulose.

Does Vinpocetine Have Side Effects?

Vinpocetine is still being subjected to numerous laboratory studies, which means this synthetic compound is considered unsafe for regular human consumption. Seek the help of a healthcare practitioner suppose you accidentally consumed Vinpocetine supplements.

Here are some of the known research side effects of Vinpocetine:

• Anxiety
• Stomach discomfort
• Sleep problems
• Headache
• Dizziness, and
• Flushing of the face

Vinpocetine and Pregnant Women

This supplement, by any name, may be harmful to pregnant women, according to an evaluated report from the National Institutes of Health’s National Toxicology Program. [R] According to the report, the compound reduced fetal weight and increased the likelihood of miscarriage in test animals.

Frequently Asked Questions

Is Vinpocetine safe?

As stated above, the nootropic under consideration may pose specific adverse effects to humans, so you should not buy Vinpocetine unless it is for research-focus endeavors.

What other SARMs can you use alongside Vinpocetine?

Noopept is another synthetic nootropic that can be stacked with Vinpocetine.

Where can you buy Vinpocetine online?

Pure Rawz is the best place to buy high-grade Vinpocetine online. We have a wide range of nootropics for sale if you are looking for such substances for your research.

You may also see the reviews on our Vinpocetine, where our customers share their experience with our research chemicals.

In order to be the best supplier of research peptides, we provide additional information (such as reference materials) with every product we sell. All of our products come with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.