Ligandrol (LGD-4033) + MK-677 (Ibutamoren) Stack

Description

What is LGD-4033 + MK-677 Stack?

Get Purerawz LGD-4033 + MK-677 stack for your research! This powerful stack combines LGD-4033, known for its possible impact on muscle and bone strength. While MK-677 might help in studying growth hormone and sleep improvement. Ideal for exploring new research possibilities, this combination is intended to assist researchers in the discovery of new knowledge regarding fat loss, hormone levels, and muscle growth.

The formula includes 10mg of LGD-4033 and 10mg of MK-677. Choose from tablets in two variants:

Tablets:

20mg per tablet with 27 tablets (totaling 540mg)

20mg per tablet with 54 tablets (totaling 1080mg)

Capsule:

20mg per capsule with 60 capsules (totaling 1200mg)

What is LGD-4033 (Ligandrol)?

CAS number	1165910-22-4
Molar Mass	338.25 g/mol
Chemical Formula	C14H12F6N2O
IUPAC Name	4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile

LGD-4033 is a research chemical known as a selective androgen receptor modulator (SARM). It connects strongly to androgen receptors, which play a key role in muscle and bone activity. Studies on animals have shown that LGD-4033 can help build muscle and support bone strength while focusing more on muscle tissue and less on the prostate. [R].

This SARM was developed by Ligand Pharmaceuticals and tested in trials. These trials found that lean body mass increased over 21 days in a dose-dependent manner without significant changes in markers linked to prostate health.[R].

How does LGD-4033 work in body composition?

LGD-4033 works by targeting AR in muscle tissue. Its potential role in lean muscle research is linked to how androgens like testosterone can promote muscle mass. Mechanisms include either boosting muscle protein synthesis or reducing muscle protein breakdown. Studies suggest that testosterone might reduce muscle proteolysis, which helps maintain muscle mass. Similar to testosterone, LGD-4033 could influence muscle tissue by promoting these pathways, leading to gains in lean muscle, though these effects require further investigation in research settings [R].

LGD-4033 potential benefits:

• May potentially increase bone mineral density [R].
• May help boost muscle mass [R][R][R]
• May also help decrease HDL cholesterol and Triglyceride levels [R]
• Potentially enhances osteoporotic bones [R][R].
• Potential treatment for muscle wasting [R]
• May boost IGF levels in test subjects
• May potentially reduce fall accidents in old test subjects[R]
• May aid in the treatment of prostate cancer [R]

What is MK677?

MK-677, also known as Ibutamoren Mesylate or LUM-201, is a research chemical designed to mimic the effects of Growth Hormone-Releasing Peptides (GHRPs), specifically growth hormone secretagogues. This compound is being explored for its potential use in research related to growth hormone deficiencies, especially in children. Studies have shown that MK-677 may stimulate GH release and increase IGF-1 levels. This makes it a valuable subject in GH-related research [R].

MK-677 is notable for its excellent oral bioavailability. Research has demonstrated that it may stimulate the release of GH in laboratory settings. Studies have explored its potential to enhance GH release and its effects on hormone levels in various research contexts.[R]

MK-677
CAS	159752-10-0
Molar Mass	624.8 g/mol
Chemical Formula	C28H40N4O8S2
IUPAC Name	2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4′-piperidine]-1′-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide;methanesulfonic acid

How does MK-677 work?

MK-677 is a research chemical used in studies to understand its effects on GH and IGF-1. When MK-677 is administered, it can increase the frequency of small pulses of GH released in the body. These small GH pulses lead to higher levels of IGF-1 after a week of treatment. This increase in IGF-1 suggests that MK-677 might help in studies related to muscle growth and other areas by affecting the levels of these important hormones.[R]

The research shows that MK-677 does not cause an increase in cortisol levels or lead to hypercortisolism. Instead, it has been discovered to have the potential to enhance the quality of sleep, particularly in the deeper stages of sleep, in test subjects.[R]

MK-677 Potential Benefits

• May potentially increase fat-free mass [R]
• May potentially help in sleep disturbances in old test subjects [R]
• May possibly help speed up bone development in old test subjects [R][R]
• A possible approach to reduce body fat, especially in overweight test subjects [R][R]
• May be able to treat growth hormone deficiency [R][R]
• May have the potential to enhance strength and lean body mass in specific test subjects. [R]

FAQS

Is MK-677 a steroid?

The substance MK-677 is not a steroid. It regulates growth hormone levels release without being a steroid or influencing androgen receptors.

What is the half-life of LGD-4033 and MK-677 in labs?

MK-677 (Ibutamoren) has a half-life of 24 hours, while LGD 4033 has 24-36 hours. This indicates both research chemicals last similarly. In combination, LGD4033 and MK-677’s identical half-lives ensure their presence. Maintaining stable levels during research makes studying their overall effects easier.

Where to buy the best LGD-4033 + MK-677 products on sale?

PureRawz is one of the top suppliers of potent formulas such as LGD-4033 + MK-677 in tablet and capsule form. You can also buy MK-677 and LGD4033 separately at PureRawz if your research requires individual administration.

To produce a quality item, we carry the item’s reference materials with every product we sell. Each of our compounds sold comes with an independent, third-party-issued Certificate of Analysis for identification, purity or concentrated natural extract, and concentration. PureRawz doesn’t sell modified items.

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Disclaimer

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with the appropriate Institutional Review Board (IRB) oversight. All preclinical research must be conducted with oversight from the relevant Institutional Animal Care and Use Committee (IACUC) following the Animal Welfare Act (AWA) guidelines.

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