Alarelin Acetate

Description

Alarelin Acetate

Alarelin acetate is a synthetic gonadotropin-releasing hormone (GnRH) agonist peptide. The peptide's structure is derived from endogenous GnRH, with specific amino-acid modifications. The modifications help increase its resistance to enzymatic degradation in experimental models.

Alarelin acetate is being researched by various analysts in reproductive endocrinology studies. The researchers also investigate the peptide in hypothalamic-pituitary-gonadal (HPG) axis regulation studies.

Moreover, researchers study Alarelin acetate to better understand GnRH receptor signalling and downstream hormone regulation pathways.

Alarelin acetate is classified as a research compound and is not approved for clinical or therapeutic use in humans.

Chemical Properties

Pubchem CID	12821051
Molecular Formula	C60H86N16O16
Synonyms	ALARELIN ACETATE 288L2XKV2J LHRHa RefChem:1076311 Leutenizing Hormone-Releasing Hormone analogue
Molecular Weight	1287.4 g/mol
IUPAC	L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline ethylamide acetic acid
Solubility	DMF: 5 mg/ml DMSO: 5 mg/ml PBS (pH 7.2): 5 mg/ml
CAS No.	79561-22-1

How Does Alarelin Acetate Work? 

Alarelin acetate appears to work in experimental models by interacting with GnRH receptors in the pituitary gonadotroph cells. The interaction influences the release of primary reproductive hormones: luteinizing hormone (LH) and follicle-stimulating hormone FSH).

Researchers believe that with constant stimulation, the GnRH receptors become less responsive and their number decreases. It ultimately reduces pituitary responsiveness in preclinical research models. The process may cause a decline in the secretion of LH and FSH in experimental research models.

Reduced gonadotropin signalling in research settings may be used to model changes in spermatogenesis, follicular development, and ovulatory signalling.

Storage and Handling Guidelines

Handling and storing of Alarelin Acetate peptide is important for long-term research use. Here are the guidelines to follow:

• Always store the Lyophilised (powder) form of Alarelin Acetate in -20°C
• The reconstituted solution can be refrigerated at 2-8°C (refrigerated)
• Use sterile bacteriostatic water or sterile saline
• Allow the vial to reach room temperature before opening
• Use sterile gloves and syringes
• Keep vials closed when not in use
• Avoid exposure to air, light, and humidity

Research Application of Alarelin Acetate

Alarelin Acetate is being researched by various medical analysts in laboratory settings for its following potential applications.

• Reproductive Endocrinology Research

The peptide is being studied to understand regulation of the hypothalamic-pituitary-gonadal (HPG) axis in research models.

• Fertility and Ovulation Research Studies

It is studied for its effects on gonadotropin release patterns and ovarian follicular signaling in experimental models. Moreover, researchers investigate the peptide for its reproductive hormone dynamics.

• Hormone-Dependent Disorder Research

GnRH analogues are widely used in endocrine research models to study hormonal suppression pathways and estrogen-dependent tissue responses.

Buy Alarelin Acetate Online

Alarelin acetate is available for laboratory research with batch documentation and analytical testing information.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

Reference Links

Yuan, F., Zhang, P., Liu, M., Li, Y., Xu, B., & Li, X. (2025). Pharmacogenomic analysis of alarelin acetate-induced hepatotoxicity: a case report and literature review. Frontiers in Medicine, 12. https://doi.org/10.3389/fmed.2025.1634101 What is Alarelin Acetate used for? (2024). Patsnap.com. https://synapse.patsnap.com/article/what-is-alarelin-acetate-used-for ‌Alarelin Acetate. (2021). Apexbt.com. https://www.apexbt.com/alarelin-acetate.html Gonadotropin-releasing hormone stimulants. (2025). Reactions Weekly, 2083(1), 58-58. https://doi.org/10.1007/s40278-025-91067-9