Alarelin Acetate

(10 customer reviews)

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Description

Alarelin Acetate – Product Information

Alarelin acetate (Gonadotropin-releasing hormone) is a known synthetic GnRH agonist. Alarelin could potentially treat endometriosis and is well-known for causing ovulation. In rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro, as well as in the induction of ovulation, Alarelin is present in higher concentrations than LH-RH.

Alarelin acetate refers to the acetate form of a hypothalamic peptide. It stimulates the pituitary gland’s release of FSH and LH.

Pure Rawz sells Alarelin Acetate for laboratory research use only since it is a synthetic chemical compound still being investigated for its possible applications. Our products come from a legitimate Alarelin Acetate supplier to ensure we provide our clients with high-quality products.

In the context of research, it is advisable to opt for bacteriostatic water when reconstituting substances rather than sterile water.

Alarelin Acetate 
CAS Number 79561-22-1
Molar Mass 1287.4
Chemical Formula C56H78N16O12
IUPAC Name N/A

What is Alarelin Acetate?

Alarelin acetate peptide has a molecular mass of 1167.3 Dalton, a molecular formula of C56H78N16O12 x C2H4O2, and a single, non-glycosylated polypeptide chain with 9 amino acids.

Alarelin acetate is a synthetic polypeptide that is an analog agonist for luteinizing hormone-releasing hormone (LH-RH). The pituitary gland secretes LH (luteinizing hormone) and FSH (follicle-stimulating hormone) in response to the release of LH-RH, which is produced in the hypothalamus.

The pro-fertility effects of LHRH are caused by these two hormones, which affect the ovaries and testes and cause the release of steroidal hormones.

In the test of rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro as well as in the ovulation induction test, the biological activity of Alarelin, a synthetic LH-RH agonist, is hundreds of times higher than that of LH-RH.

Possible Applications of Alarelin Acetate

Alarelin Acetate Peptide and Ovulation

For 60 days, the effects of a gonadotropin-releasing hormone analog (GnRH-a, alarelin) on ovarian development and the related gene expression in the pituitary gland of the tilapia (Oreochromis niloticus) were studied. [R]

This had implications for novel GnRH-based techniques created to control sexual maturation in tilapia because Alarelin treatment promoted ovarian and follicular development. [R]

Despite such positive results, more clinical trials are needed.

Alarelin Acetate Peptide and Gastric Acid Secretion

Alarelin, a GnRH analog, has demonstrated the ability to prevent gastric acid secretion by directly impacting parietal cells and inhibiting vagus function.

According to clinical research, rat gastric parietal cells may produce GnRH and modulate their physiological function in both an autocrine and paracrine manner. [R]

This outcome is insufficient, and more in-depth studies are sought.

Alarelin Acetate Peptide and Endometrial Carcinoma

In both newborn and adult female rats, it causes desensitization in the pituitary and lowers serum estradiol levels and ovarian and uterine weight. When given in doses of 20, 40, and 80 g/kg, Alarelin slows the growth of tumors in a mouse xenograft model for HEC-1-B human endometrial carcinoma. [R]

More large-scale studies are required here.

How Does Alarelin Acetate Peptide Work?

According to particular research, Alarelin could significantly enhance the ratio of the G1 phase and may also decrease the ratio of the S phase of the GSMC in rats. [R]

Gonadotrophin-releasing hormone (GnRH) from the hypothalamus binds to particular receptors on pituitary gonadotrophs. As a result of their activation, inositol 1,4,5-triphosphate (Ins(1,4,5)P3) and diacylglycerol are produced along with the breakdown of phosphoinositides.

Both Ca2+ release from intracellular stores and protein kinase C activation, which are necessary for gonadotrophin synthesis and secretion, are triggered by these second messengers. Gonadotrophin secretion is suppressed when GnRH receptors are activated for an extended period of time. The primary mode of action of agonistic GnRH analogs is this process.

GnRH antagonists, in contrast, block GnRH-induced signal transduction and, as a result, gonadotrophin secretion by competing with GnRH for receptors on gonadotroph cell membranes.

Frequently Asked Questions

What is the use of Alarelin Acetate peptide?

Alarelin is well-known for inducing ovulation. Alarelin acetate is the acetate form of a hypothalamic peptide that stimulates the pituitary gland’s release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), resulting in an increase in circulating sex hormones.

How to store Alarelin Acetate peptide?

Alarelin acetate manufacturer advises that this chemical that has been lyophilized should be kept desiccated below -18°C even though it is stable at room temperature for 3 weeks. Alarelin stock solutions should be stored after reconstitution at 4°C for 2–7 days and below -18°C for later use. It is advised to include a carrier protein (0.1% HSA or BSA) for long-term storage. Do your best to prevent freeze-thaw cycles.

Where can you buy Alarelin acetate?

Pure Rawz is the best place to buy Alarelin Acetate online. Our Alarelin Acetate catalog consists of high-quality chemical products that have the correct molecular weight to ensure you get true value for your money.

Pure Rawz is also home to other research compounds, such as peptides and SARMS, that are widely used for scientific studies.

In order to be the best supplier of research chemicals, we provide reference materials with every product we sell. All of our products come with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.

 

Disclaimer
This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY.
All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).
Our content is intended to be used and must be used for informational purposes only. It is very important to do your own analysis and research from Trusted Sources before making any purchase based on your own personal circumstances. You should independently research and verify any information that you find on our Website and wish to rely upon.
By completing and paying for your order, you agree to our Terms and Conditions. Customer satisfaction is our number one priority, if you are not 100% satisfied with the product you received, please contact us at [email protected]
ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY not for veterinary or human usage.

10 reviews for Alarelin Acetate

  1. Kyle Marcs

    Amazing service and very fast shipping , Extremely happy with you guys

  2. Greg Morris

    Great product and fast shipping

  3. Colvey Peters

    I cannot wait to use this. Delivery was super fast this time around. Thank you

  4. RitaRalph Watson

    My husband and I have been trying to conceive for years with no luck. Saw fertility specialists but no results. I started taking these and got pregnant a few months later! I got pregnant naturally at 42 years old. I really think these helped big time!

  5. Anonymous

    Hoping for good results. Fingers crossed to have a baby by next year. Thanks to my friend who highly recommended you guys especially this Alarelin Acetate product. We are really excited about the outcome for the next few days or weeks.

  6. Trever Nitzsche

    This stuff is super!

  7. Henryl Arthur

    Thank you for getting me through the payment and shipping process. Your customer service deserves lots of praise.

  8. Bruce G

    Research results pending.

  9. Anonymous

    I tried different Alarelin Acetate’s from other vendors, but this one hits the mark. It’s the only one I’d recommend from now on.

  10. Anonymous

    Quality is top-notch!

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