Glutathione

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Description

Glutathione – Product Information

  • Glutathione Nasal Spray is offered at 200mg per ml, delivering 24mg per spray, with a total volume of 12ml and an overall content of 2400mg.

The antioxidant system, which protects the body from free radicals at the cellular level, must include glutathione. Among animal living cells, this hormone may be the most abundant intracellular thiol.

Reduced glutathione plays a role in DNA synthesis and repair, amino acid transport, vitamin C’s antioxidant activity, and the detoxification of toxic substances.

Reduced glutathione is being researched as a possible dietary supplement that, in addition to supporting skin health and skin elasticity, may have favorable effects on the body due to its antioxidant properties. This substance, however, is not meant to be used in the treatment, prevention, or diagnosis of any disease.

Glutathione
CAS Number 70-18-8
Molar Mass 307.32 g/mol
Chemical Formula C10H17N3O6S
IUPAC Name (2S)-2-Amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]carbamoyl}butanoic acid

What is Glutathione?

All human cells produce glutathione, an antioxidant that works to stop cells from becoming damaged by oxidizing free radicals. L-glutamate, cysteine, and glycine are the amino acids used in the liver to make it. The cell has high amounts of glutathione at the same levels as potassium, cholesterol, and glucose. [R]

By having the potential to prevent the body’s ability to produce free radicals, glutathione serves as a co-factor in preventing oxidative stress. When research subjects are exposed to poisons like radiation or tobacco smoke, chemicals known as free radicals are created. It has been suggested that free radicals have a role in several illnesses, including cancer and heart disease.

It may also aid with the demand for protein production and tissue repair, in addition to preventing the oxidation caused by free radicals. However, levels of glutathione in subjects can drop when glutathione itself is exposed to oxidative stress, such as with harmful substances. Glutathione levels can potentially be reduced by illness, bad diet, aging, and too much stress, which may also contribute to poor health.

The precursor to glutathione, N-acetylcysteine (NAC), has been used to increase glutathione levels.

How does Glutathione Work?

The detoxification of endogenous and xenobiotic compounds involves both glutathiones. In addition to encouraging body and cell excretion, it immediately neutralizes a variety of oxidative substances. [R]

It is believed that there are at least four separate mechanisms by which glutathione facilitates the transport of toxins across the plasma membrane, the most significant of which is the production of glutathione S-conjugates. [R]

Low glutathione and transferase activity are associated with chronic alcohol and chemical toxin exposure, cadmium exposure, AIDS/HIV, macular degeneration, Parkinson’s disease, and other neurodegenerative illnesses. [R]

Many oxidants, such as superoxide anion, hydroxyl radicals, nitric oxide, and carbon radicals are scavenged by glutathione. Glutathione detoxifies hydroperoxides, peroxynitrites, and lipid peroxides catalytically. [R]

Reusing vitamins like C and E is another way glutathione shields cells from oxidants. [R]

Glutathione Research

It is believed that certain medical diseases, such as chronic disease and neurodegenerative diseases, are linked to glutathione deficiency.

Purerawz sells Glutathione for research purposes only.

Glutathione and Oxidative Damage

Glutathione’s antioxidant qualities unquestionably contribute to the majority of its potential health advantages. According to the National Cancer Institute, oxidative stress, which happens when the ratio of free radicals to antioxidants tilts in favor of free radicals, can cause cell damage. [R]

According to research, this mechanism contributes to accelerated aging as well as cancer, autoimmune diseases, cataracts, rheumatoid arthritis, and cardiovascular and neurological diseases. [R]

According to a 2014 study, the amino acid complex glutathione has the potential to protect against oxidative stress, and its depletion is also linked to such conditions. [R] Research on the advantages of liposomal glutathione supplementation frequently examines whether replacing it in research subjects can aid in reducing oxidative stress, improving health, and protecting against the aging process.

Glutathione levels, for instance, are low in those with Parkinson’s disease, a neurodegenerative condition that impairs movement. A small, double-blind, placebo-controlled trial is just one example of the research that has been sparked by this knowledge to see if supplements can potentially aid with the illness’ symptoms. [R] According to the study’s findings, Parkinson’s disease patients who received intranasal glutathione three times a day for three months, experienced some improvement in their symptoms.

Eight years prior, the findings of a randomized, placebo-controlled, double-blind, pilot trial of Parkinson’s disease patients receiving glutathione intravenously were published in the journal ‘Movement Disorders’. The results suggested “the possibility of a minor clinical benefit.” [R]

Glutathione and Alcohol

Alcohol metabolism also involves glutathione. [R] Acetaldehyde, a byproduct of ethanol (alcohol) processing in the body, is carcinogenic. L-cysteine, an amino acid found in glutathione, converts acetaldehyde into water and carbon dioxide, which are then excreted in the urine. Glutathione levels are decreased when alcohol is excessively consumed.

Gluthatione is being researched in the hope that it will neutralize the effects of alcohol or Tylenol use.

A small research study found that subjects with non-alcoholic fatty liver disease who were given glutathione orally experienced positive results. [R]

Glutathione and Insulin Resistance

As mentioned above, Glutathione production declines with age. Using both human and animal studies, Baylor School of Medicine researchers investigated the function of glutathione in aging-related insulin resistance and weight management. According to study results, low glutathione levels are linked to lower rates of fat burning and higher rates of fat storage in the body. [R]

Glutathione and Peripheral Arterial Disease

The condition known as peripheral arterial disease is brought on by plaque buildup in the peripheral arteries. It most frequently occurs in the legs. According to one study, glutathione increased circulation, enabling study participants to walk farther without experiencing any pain. [R]

Glutathione Levels and Auto Immune Function

According to a recent study, glutathione has the potential to affect the body’s immune response by boosting or suppressing it. Diseases with an autoimmune component damage particular cells’ mitochondria. By scavenging free radicals, glutathione may potentially protect the mitochondria of the cell. [R]

Glutathione and Diabetes

Low levels of glutathione are related to an increased risk of chronic higher levels of blood sugar. Tissue damage and oxidative stress may result from this. A study indicated that adding cysteine and glycine dietary supplements to the diet had the potential to increase the levels of glutathione. [R]

FAQs

Is Glutathione Safe?

Glutathione might have certain health advantages, however it is not advised to take this experimental medication as a food supplement. The conclusive medicinal implications of glutathione require further study.

Reduced Glutathione vs Glutathione

There isn’t much of a difference between glutathione and reduced glutathione. Nevertheless, there are two different kinds of glutathione: reduced glutathione (GSH or L-glutathione reduced), which is the active form, and oxidized glutathione (GSSG), which is inactive.

Can you stack Glutathione?

L-carnitine may combine well with reduced glutathione. The two together have been shown to protect the plasma membrane in the event of oxidative damage, leading to enhanced sperm shape and mobility, as supported by a specific study. [R]

Purerawz also sells S Acetyl l Glutathione For Sale.

Where can you buy Glutathione?

PureRawz is the best place to buy the highest-quality glutathione online.

In order to be the best supplier of research chemicals, we provide reference materials with every product we sell. All of our products come with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.

We offer free international shipping on all orders above $100. You can pay for your purchase through various methods, including PayPal and Bitcoin. We sell liquid, powder, and capsule high-quality TUDA formulations. All the formulations are equally high-quality.

Summary

The body’s cells produce glutathione, a master antioxidant. As we age, experience stress, and are exposed to toxins, its levels decline. Increasing glutathione may potentially have a variety of positive benefits and health effects, including a decrease in oxidative stress.

However, Purerawz sells Glutathione for research purposes only.

Disclaimer

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).

Our content is intended to be used and must be used for informational purposes only. It is very important to do your own analysis and read research from Trusted Sources before making any purchase, based on your personal circumstances. You should independently research and verify any information that you find on our Website and wish to rely upon.

By completing and paying for your order, you agree to our Terms and Conditions. Customer satisfaction is our number one priority. If you are not 100% satisfied with the product you received, please contact us at [email protected]

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human usage. Stock is subject to availability

 

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