Description
IGF-1 DES Product Overview
IGF-1 DES (Insulin-Like Growth Factor-1 DES 1-3) -synthetic peptide derived from insulin-like growth factor-1 (IGF-1). This compound is primarily studied to evaluate its interaction with IGF-1 and related intracellular signaling systems. Research with IGF-1 DES focuses on molecular mechanisms associated with peptide-receptor binding and downstream biochemical pathways.
| Property | Value |
| Chemical Name | Insulin-Like Growth Factor-1 DES(1-3) |
| Synonyms | IGF-1 DES, Des(1-3) IGF-1 |
| CAS Number | 946870-92-4 |
| Molecular Formula | C331H515N97O98S7 |
| Molecular Weight | 7312.4 g/mol |
| Peptide Length | 67 amino acids |
Research Applications of IGF-1 DES
IGF-1 DES has been examined in in vitro experiments and biochemical investigations designed to evaluate peptide-receptor interactions and downstream molecular responses.
Research may include cellular signaling pathway analysis, receptor binding and affinity studies, gene expression pathway investigations, protein phosphorylation pathway analysis, and molecular signaling cascade characterization.
In laboratory environments, IGF-1 DES is commonly used in experimental frameworks that analyze:
- Peptide-receptor binding mechanisms
- Intracellular signaling pathways associated with IGF-1 receptor activation
- Molecular interactions involving growth factor signaling systems
- Cellular communication networks mediated by peptide hormones
Working Mechanism
IGF-1 DES is related to endogenous IGF-1 but lacks the first three amino acids. This modification alters the peptide structure and has been investigated for its influence on receptor interaction dynamics in experimental models.
Laboratory studies have examined the interaction of IGF-1 DES with the insulin-like growth factor-1 receptor (IGF-1R) located on cellular membranes. Binding to this receptor may initiate intracellular signaling cascades commonly associated with peptide growth factor pathways.
Why Buy from PureRawz
Research institutions and laboratories often prioritize sourcing compounds from suppliers that provide transparent documentation and verifiable quality data. Materials supplied by PureRawz are prepared for laboratory and experimental environments where compound identity and documentation are required.
Each batch is accompanied by third-party analytical testing, commonly performed using techniques such as High-Performance Liquid Chromatography (HPLC) or similar laboratory methods. These analyses verify compound identity, composition, and reported purity parameters.
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Research Disclaimer
This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing.
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Reference Links
De Meyts, P. (2004). Insulin and its receptor: structure, function, and evolution. BioEssays.
https://doi.org/10.1002/bies.20089
Le Roith, D., Bondy, C., Yakar, S., Liu, J., & Butler, A. (2001). The somatomedin hypothesis: IGF-1 and its receptor. Endocrine Reviews.
https://doi.org/10.1210/edrv.22.1.0419
Hwa, V., Oh, Y., & Rosenfeld, R. (1999). The insulin-like growth factor-binding protein superfamily. Endocrine Reviews.
https://doi.org/10.1210/edrv.20.6.0388
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