Description

LGD-4033 + YK-11 + S23 Formula

What is LGD-4033 + YK-11 + S23 Formula ?

Studies have frequently looked at the potential impacts of LGD-4033, YK-11, and S23 on strength and muscular mass. The potential of LGD-4033 for increasing muscle mass and bone density has been studied. YK-11, another SARM, has been suggested to act as a myostatin inhibitor. This could possibly lead to significant muscle development. S23 is another SARM that has been researched recently. It may have anabolic effects that are greater compared to those of LGD-4033.

Combining these research chemicals may open up various avenues for potential studies, that may impact benefits on building muscle, fat loss, strength gains, and more.

LGD-4033 + YK-11 + S23 Formula are available in two variants:

• Tablets include 75mg LGD-4033, YK-11, and S-23. 20 (1500mg) or 40 (3000mg) tablets are available.
• Liquid: 100mg LGD-4033, YK-11, and S-23 per ml. 3000mg in a 30ml bottle.

What is LGD 4033?

CAS	1165910-22-4
Molar Mass	338.25 g/mol
Chemical Formula	C14H12F6N2O
IUPAC Name	4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile

Ligrandol (LGD-4033) is an oral, non-steroidal selective androgen receptor modulator. It was synthesized at Ligand Pharmaceuticals[R]. This research chemical is designed to bind with high affinity and selectivity to the androgen receptor, with a Ki of approximately 1 nM. In animal models, LGD-4033 has demonstrated anabolic activity in muscle tissue. It has shown both anti-resorptive and anabolic effects. It has been noted to potentially increase lean body mass [R]. This makes it valuable for potential research on muscle growth and related areas.

How does LGD 4033 work?

LGD-4033 was studied for potentially treating muscle atrophy and osteoporosis.. It may improve protein synthesis and protect bone health by exclusively activating androgen receptors without significantly altering other hormonal pathways [R]. Studies investigating its safety and efficacy profiles continue to be performed to gain a better understanding of its possible uses and effects.

LGD 4033 research potential:

• It may potentially enhance muscle growth, contributing to increased lean mass [R]
• It may improve bone density [R]
• It may potentially exhibit anabolic effects in bones and muscles [R]
• It has the potential to assist in injury recovery [R]

What is YK-11?

CAS	51370003-76-1
Molar M	430.534 g/mol
Chemical Formula	C27H42O5
IUPAC Name	(1S,2S,4S,5’R,6R,7S,8R,9S,12S,13R,16S,18R)-16,18-dihydroxy-5′,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2′-oxane]-19-one

YK-11 is a partial Androgen Receptor (AR) agonist[R]. This research molecule is unique since it acts like SARMs yet has anabolic steroid properties[R]. YK-11 indirectly inhibits myostatin, which limits muscle growth. By blocking myostatin, YK-11 may promote follistatin production, which regulates androgen signaling and muscle hypertrophy and hyperplasia. This mechanism of action may support research focused on muscle development.[R]

How does YK11 work?

Myostatin, which restricts muscle growth, may be inhibited by YK-11. In research settings, YK-11 has shown the ability to upregulate key anabolic targets such as MyoG, Mfy5, and MyoD in C2C12 myoblast cells, which are crucial for muscle development. The substance may also impact NF-κB signaling pathways, perhaps reducing muscle atrophy. As an AR agonist, YK-11 does not fully activate the AR, which may alter its interaction with other research compounds[R]. Despite these findings, YK-11 has not been tested in human clinical trials, and its side effects and safety dosage are still under investigation

YK-11 Investigations:

• It has the potential capacity to stimulate rapid muscle growth. [R][R]
• It may help to strengthen the muscles. [R]
• It may potentially decrease fat mass. [R]

What is S23?

CAS	1010396-29-8
Molar M	416.76 g/mol
Chemical Formula	C18H13ClF4N2O3
IUPAC Name	(2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

S-23 is a research chemical that has been studied for its potential in hormonal male contraception. This drug is a SARM developed by GTX Incorporation. According to research, S-23 is the strongest SARM on the market, stronger than ligandrol (LGD-4033), Ostarine (MK2866), and Andarine. [R]

How does S23 work?

Potent androgen receptor agonist S-23 binds robustly and selectively to ARs in the body. This binding promotes anabolic activity to maintain muscle mass and body composition. In animal models, S-23 maintains muscle weight and reduces fat accumulation at low doses. In conjunction with estrogen (EB), S-23 suppresses sperm production while sustaining muscle weight and other androgen-dependent activities. With high oral absorption, this combination treatment for reversible male contraception is promising [R]. Further research results are needed to confirm its efficacy and safety in different settings.

S23 Investigations:

• It may increase muscle mass [R].
• It may improve body fat. [R]
• It has shown potential in supporting bone health. [R]
• It may inhibit conception in mating trials by suppressing spermatogenesis [R][R]

FREQUENTLY ASKED QUESTIONS

What is the half-life of LGD 4033, YK-11 and S23?

S23 has a half-life of 12 hours, while LGD-4033 has a half-life of 24 to 36 hours. The half-life of YK-11 is not established in the scientific literature; however, some sources estimate it to be between 6 and 8 hours.

Is LGD-4033 + YK-11 + S23 Formula legal or FDA-approved?

The US Food and Drug Administration (FDA) has not yet approved the use of LGD 4033, YK-11, or S23 in clinical practice, although there has been extensive research, this needs further clinical trials including the need for Post-Research Recovery Protocols.

Where to buy the best LGD-4033 + YK-11 + S23 Formula for strength research?

PureRawz is one of the top suppliers of potent formulas such as LGD-4033 + YK-11 + S23 Formula in tablet and liquid form. You can also buy S-23, YK-11, and LGD4033 separately at PureRawz if your research requires individual administration. Other peptides or sarms are also available, such as RAD140, S4 andarine which may also aid research for bulking, lean muscle mass, or its impact on testosterone.

To produce a quality item, we carry the item’s reference materials with every product we sell. Each of our compounds sold comes with an independent, third-party-issued Certificate of Analysis for purity identification.

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Disclaimer

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with the appropriate Institutional Review Board (IRB) oversight. All preclinical research must be conducted with oversight from the relevant Institutional Animal Care and Use Committee (IACUC) following the Animal Welfare Act (AWA) guidelines.

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