T3 Liothyronine Sodium + SR-9011 + Yohimbine – Product Information

is a research product that combines T3 Liothyronine Sodium, SR-9011, and Yohimbine to investigate their potential synergistic effects. T3 Liothyronine Sodium is a compound known for its impact on thyroid activity and metabolism. SR-9011, a REV-ERB agonist, is believed to influence circadian rhythm and metabolic processes. Yohimbine, an alpha-2 adrenergic receptor antagonist, may have effects on various physiological processes such as blood flow and fat metabolism.

The combination of T3 Liothyronine Sodium, SR-9011, and Yohimbine in offers researchers the opportunity to explore their collective impact on metabolism, energy regulation, and potential fat loss. However, it is crucial to reiterate that  is strictly intended for research purposes.

• consists of T3 Liothyronine, SR-9011, and Yohimbine.
• Transdermal is offered as 60ml/17.6mg per ml/1g.
• Injectables is offered as 10ml/100mg per ml/1g.

T3 Liothyronine Sodium

T3 Liothyronine Sodium (or more specifically, thyroid hormones in general) are investigated for their interactions with fat mass since, in survey research, thyroid activity may be related to fat mass and BMI. A recent study on the effects of T3 on rats found that the increased expression of thyroid hormone receptor beta (T3’s receptor) that is increased during caloric restriction is not abolished by T3 supplementation and that T3 supplementation leads to increased leptin gene expression.

Overall, the data seem to suggest that T3 does not necessarily spike metabolic rate but that it minimizes a decline seen in metabolic rate due to prolonged caloric restriction. This warrants a massive potential of T3 as a possible weight loss aid.

T3 Liothyronine Sodium
CAS Number	6893-02-3
Molar Mass	650,9735 g/mol
Chemical Formula	C15H12I3NO4
IUPAC Name	sodium;(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate

SR-9011

SR-9011 is a research compound that falls under the category of REV-ERB agonists. It is a synthetic compound that has been developed for research purposes to explore its potential effects on various physiological processes. A recent study on diet-induced obese mice treated with SR9009 and SR9011 (i.e., two times a day for 30 days) has been reported to display decreased fat mass and markedly improved dyslipidemia and hyperglycemia. The activation of REV-ERB leads to the enhancement of circadian rhythm observed in mice. This affects behavior, sleep cycle, and some functions related to an increment in energy production.

SR-9011
CAS Number	1379686-29-9
Molar Mass	479.04 g/mol
Chemical Formula	C23H31ClN4O3S
IUPAC Name	3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide

Yohimbine

Yohimbine is a compound derived from the bark of the yohimbe tree (Pausinystalia yohimbe) and is of interest in research fields. It is classified as an alpha-2 adrenergic receptor antagonist, meaning it blocks the action of these receptors. Yohimbine has been studied for its potential effects on various physiological processes, such as its impact on blood flow, sexual function, and potential role in fat metabolism.

Yohimbine
CAS Number	146-48-5
Molar Mass	354.450 g/mol
Chemical Formula	C21H26N2O3
IUPAC Name	17 α-hydroxy-yohimban-16 α-carboxylic acid methyl ester

Disclaimer

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).

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