Buy Deslorelin For Sale – Product Details
Deslorelin is a synthetic analogue of gonadotropin-releasing hormone (GnRH). It is used to manage artificial insemination in horses, regulate reproduction in dogs, and manage adrenal disease in ferrets. Deslorelin is also used to induce ovulation in mares and cattle.
In humans, deslorelin has undergone extensive testing as a potential treatment for children with precocious puberty and also for the treatment of prostate cancer. Deslorelin is currently undergoing trials for the treatment of fibroids, endometriosis, and menorrhagia.
Pure Rawz sells Deslorelin for laboratory and research use only.
|Molar Mass||1282.475 g·mol−1|
What is Deslorelin?
Deslorelin is a synthetic analog of gonadotropin-releasing hormone (GnRH). The GnRH controls the release of luteinizing hormone (LSH) and follicle-stimulating hormone (FSH). Both hormones stimulate the testes in males and ovaries in females to produce sex hormones. [R][R]
Like other synthetic GnRH analogs, deslorelin also stimulates the release of pituitary gonadotropins (LH and FSH). However, it’s different from other synthetic GnRH analogs in one critical way. That is that deslorelin is reportedly 100 times more potent than GnRH. [R][R]
Deslorelin has been approved by the US FDA for inducing ovulation in cyclic estrous mare and managing adrenal glands disease in ferrets. In the EU, deslorelin treatment is used for healthy, sexually mature male dogs and male ferrets to make them temporarily infertile. [R][R]
This synthetic gonadotropin-releasing hormone is available under many brand names, including SucroMate Equine, Superlorin F, Superlorin 12, and Superlorin-6. At the time of writing, deslorelin hasn’t been approved for any clinical use by any regulatory authority.
How does Deslorelin Work?
Deslorelin acts like the natural hormone GnRH to control the secretion of hormones involved in fertility. In dogs and ferrets, a continuously low dose of deslorelin has been shown to suppress the production of LH and FSH and, by extension, sperm to make the animals temporarily infertile. [R]
What follows is a summary of the existing research on deslorelin. The information given in this section is for educational purposes only. It doesn’t constitute medical advice. Speak to a qualified medical professional to know more about deslorelin acetate.
1) Deslorelin and Infertility
In healthy males, deslorelin treatment (50 µg or higher doses) for up to 10 weeks reportedly caused decreased or loss of fertility. These effects were shown to be reversible. All injection sites swelling resolved within days of administration. [R]
A preclinical study investigated the contraceptive effects of implants containing deslorelin in female mice. Fertility was successfully inhibited for 428 – 602 days post-treatment. The duration of contraception ranged from 344 to 761 days following the implant’s administration. [R]
In male and female cats, sustained-release formulation deslorelin implants have been shown to generate effective, safe, and reversible long-term contraception. In pubertal cats, a 4.7 mg deslorelin implant suppressed steroid sex hormones for at least 15 months. [R]
2) Deslorelin and Precocious Puberty
Precocious puberty often leads to short adult height.
A clinical study was conducted to investigate whether deslorelin treatment normalized the adult height of children with precocious puberty. The study involved 161 children with this condition. [R]
Results from the study show that deslorelin treatment improved the adult height of the patients but didn’t fully restore the height to the patients’ genetic potential. The researchers hypothesize that better results could be obtained by administering deslorelin at a younger bone age. [R]
3) Deslorelin and Prostate Cancer
A cell-based study investigated whether deslorelin could improve the potency of docetaxel, a drug used to enhance the survival of prostate cancer patients. [R]
Final results indicated that the deslorelin-docetaxel therapy had enhanced anti-proliferative, anti-tumor, and apoptotic efficacy by several folds in prostate cancer therapy. The combined drug also retained the pharmacologic effects of both docetaxel and deslorelin. [R]
4) Deslorelin and Endometriosis
Endometriosis is a painful condition in which tissue similar to the womb’s lining grows in other places, such as fallopian tubes and ovaries. It can affect women of any age. [R]
In a clinical study, women with pelvic pain and confirmed endometriosis were treated with a six-month course of daily intranasal deslorelin with a concurrent administration of either transdermal estradiol, intranasal estradiol, or intranasal estradiol + testosterone. [R]
The most significant reduction in the severity of endometriosis symptoms and signs occurred in the daily intranasal deslorelin with low dose estradiol + testosterone treatment group. No injection site swelling was reported, and incidences of hot flashes were reportedly minimal. [R]
5) Deslorelin and Uterine Fibroids
Uterine fibroids are non-cancerous growths that develop in or around the womb.
A clinical study reported that deslorelin treatment effectively reduces pain, bleeding, and uterine volume in women with symptomatic uterine fibroids. Notably, the improvements occurred without any changes to bone mineral density. [R]
How to Handle Deslorelin?
Pure Rawz doesn’t sell deslorelin for human or veterinary use.
Pregnant women and women of childbearing age should exercise caution when handling this product. Accidental human injection may lead to injection site swelling and disruption of the menstrual cycle. If accidental administration or exposure occurs, immediately consult your doctor.
Where to Buy Deslorelin Online?
Pure Rawz is the best place to buy the highest-quality Deslorelin online.
In order to be the best supplier of research chemicals, we provide reference materials with every product we sell. All of our products come with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.
We offer free international shipping on all orders above $100. You can pay for your purchase through various methods, including PayPal and Bitcoin. We offer a material safety data sheet on this synthetic gonadotropin-releasing hormone agonist.
Deslorelin is a synthetic analog of GnRH. Its intramuscular injection is reportedly capable of inducing ovulation within 48 hours of treatment in cyclic estrous mares with an ovarian follicle 30 to 40mm in diameter. Deslorelin has also been shown to cause temporary infertility in multiple animals.
Pure Rawz sells Deslorelin for scientific, laboratory, and research purposes only.
By completing and paying for your order, you agree to our Terms and Conditions. Customer satisfaction is our number one priority, if you are not 100% satisfied with the product you received, please contact us at email@example.com