Description

Eros (Mirodenafil + Amino Tadalafil + SR-9011 + GW-0742) Combined Formula

Compounds that boost physical and sexual performance are becoming more popular in research. Stamina and cardiac health are fundamental factors in overall sexual performance. These contribute to endurance and the ability to maintain arousal levels.

 

With the help of this ‘Quad Combined Formula,’ researchers can explore the combined benefits of Phosphodiesterase type 5 (PDE5) inhibitors. These compounds are coupled with SR-9011 and GW0742. This research combined-formula may potentially assist in muscle growth and metabolic health. It could also support studies on sexual function and circadian rhythm regulation.

 

Each EROS Tablet comprises 50mg of Mirodenafil, 30mg of Amino Tadalafil, 10mg of SR-9011, and 10mg of GW-0742. This results in a total of 2400mg, comprising 100mg per tablet for 24 tablets.

 

Phosphodiesterase type 5 (PDE5I) inhibitors in erectile dysfunction

Erectile function is enhanced with PDE5 inhibitors. These include nitric oxide (NO) and cyclic guanosine monophosphate (cGMP). These drugs are known for potentially treating ED, especially in subjects with diabetes. Each type of PDE5 inhibitor has unique strengths and weaknesses. Their applications range from pulmonary arterial hypertension (PAH) to managing urinary symptoms and benign prostatic obstruction. Like vardenafil, this combined-formula uses PDE5 inhibitors like the following:

 

Mirodenafil

CAS	862189-95-5
Molar Mass	531.7 g/mol
Chemical Formula	C26H37N5O5S
IUPAC Name	5-ethyl-2-[5-[4-(2-hydroxyethyl)piperazin-1-yl]sulfonyl-2-propoxyphenyl]-7-propyl-3H-pyrrolo[3,2-d]pyrimidin-4-one

What is Mirodenafil?

One drug for erectile dysfunction (ED) is called mirodenafil, which is a PDE5 inhibitor. Because it can target PDE5, an enzyme necessary for erectile function, mirodenafil is effective. With few adverse effects, this accuracy helps to optimize its advantages.

How do Mirodenafil peptides work?

Being a PDE5 inhibitor, it prevents cGMP from being broken down. Because it binds to the enzyme that breaks it down, cGMP is an essential component for erections. In particular tissues, this mechanism increases the production of cGMP. As smooth muscles relax, blood flow may be maintained. Increased blood flow during stimulation is made possible by this relaxation.

In the end, this leads to potential better sexual function and firmer erections.

Mirodenafil potential benefits:

• It may help enhance cognitive function. Suggesting its potential as a therapeutic approach for Alzheimer’s disease.
• It may improve erectile function.
• It may be a potential alternative for treating fibrosis in systemic sclerosis.
• It may be a potentially treat benign prostatic hyperplasia accompanied by ED 
• It may also treat other cancers such as lung cancer, prostate, colorectal, brain, etc. 
• It has the potential to exhibit protective effects on bladder function. Thus suggesting its potential therapeutic application for chronic bladder ischemia-induced bladder dysfunction 

Amino Tadalafil

CAS	385769-84-651370003-76-1
Molar Mass	390.4 g/mol
Chemical Formula	C21H18N4O4
IUPAC Name	2R,8R)-6-amino-2-(1,3-benzodioxol-5-yl)-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione

What is Amino Tadalafil?

Amino Tadalafil is another PDE5 inhibitor known for its potential in type II diabetes-related ED. It is also an approved treatment for pulmonary arterial hypertension (PAH).

Tadalafil exhibits exceptional selectivity for PDE5, surpassing other structurally similar PDE inhibitors by at least 9,000 times. Tadalafil has 80% bioavailability but a slower absorption time than other PDE5I.

How does Amino Tadalafil work?

Amino Tadalafil, a homolog, relaxes smooth muscles and increases blood flow. This can sustain penile erection . Amino Tadalafil may also potentially protect against metabolic stress-induced cardiac dysfunction. It does this by activating SIRT1, a mammalian homolog of Silent Information Regulator (Sir)2. SIRT1 is an enzyme responsible for regulating aging and ROS in the heart . SIRT1 controls PGC-1α, a regulator of mitochondrial biogenesis. It also acts as a coactivator of energy homeostasis-related transcription factors.

Aside from its well-known effect on improving erectile function, Amino Tadalafil may:

• It may protect against myocardial ischemia. 
• It may be an alternative melanoma immunotherapy influencing enhanced antitumor immunity
• It may potentially treat benign prostatic hyperplasia (BPH) and other urological disorders .
• It may help reduce platelet-induced hypercoagulation developing multiple organ failure syndrome .
• It may promote increased lean muscle mass .

SR-9011

CAS	1379686-29-9
Molar Mass	479.0 g/mol
Chemical Formula	C23H31ClN4O3S
IUPAC Name	3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide

What is SR-9011?

SR-9011 is a synthetic agonist of REV-ERB, a transcription repressor or nuclear receptor. REV-ERB regulates the body’s rhythms in activity, sleep, and metabolism. The functions of REV-ERBs are greatly ligand-dependent. Interaction with exogenous synthetic ligands like SR-9011 can disrupt the normal circadian rhythm. This disruption occurs by altering intracellular circadian locomotor output cycles (CLOCK) machinery.

How does SR-9011 work?

SR-9011 is more effective than GSK4112 despite similar pharmacokinetics. It binds irreversibly with both REV-ERB&alpha and REV-ERBβ. This binding triggers changes in metabolic gene expression. These changes may lead to shifts in circadian behavior and metabolic gene reprogramming. This reprogramming in the liver, skeletal muscle, and adipose tissue may contribute to increased energy expenditure .

Evidence suggests that SR-9011 may affect hypothalamic and hepatic Per2 gene circadian expression. This suggests a connection between circadian rhythms and metabolic effects . However, its influence on other clock genes varied across these tissues. This indicates distinct effects on central and peripheral circadian rhythms. The findings demonstrate SR-9011’s detailed circadian and metabolic regulation.

SR-9011 may help in:

• It may potentially help suppress the growth of osteosarcoma cells and breast cancer cells.
• It may potentially improve dyslipidemia and hyperglycemia. This is done by aiding weight loss & fat mass reduction.
• It may also help in improving blood sugar and cholesterol levels.

 

GW0742

CAS	317318-84-6
Molar Mass	471.5 g/mol
Chemical Formula	C21H17F4NO3S2
IUPAC Name	2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid

What is GW0742?

GW0742 is a potent & highly selective full agonist of the peroxisome proliferator-activated receptor delta (PPARδ). PPARδ is a key regulator of metabolism, glucose control, and inflammation. At lower concentrations, GW0742 acts as a PPARδ agonist. However, at higher concentrations, it surprisingly acts as a pan-nuclear receptor antagonist. This inhibits the activity of vitamin D receptors, AR, and other nuclear receptors. Thus, VDR target gene expression decreases, and cell differentiation is disrupted.

How does GW0742 work?

GW0742 binds to and activates PPARδ. This promotes PPARδ to release proteins that bind to specific DNA sequences. These proteins regulate energy, glucose, and lipid metabolism genes. The activation of PPARδ signals the body to increase fatty acid oxidation. This provides more energy needed for bodily functions, especially for the heart. GW0742 may help regulate genes involved in fatty acid oxidation and mitochondrial function. Inefficient energy production or deletion of GW0742 can potentially lead to heart failure. This is due to decreased contractility and increased heart workload.

GW0742 may:

• It may help protect lungs from cancerous lung injuries.
• It may serve as a potential therapeutic agent for pulmonary inflammation and damage.
• It may help manage weight by increasing insulin sensitivity & hepatic energy metabolism.
• It may potentially prevent or mitigate neuroinflammation and cognitive impairment.

Frequently Asked Questions

Where to Buy the Best Eros  (Mirodenafil + Amino Tadalafil + SR-9011 + GW-0742) Combined Formula?

PureRawz is a leading source for purchasing potent formulations for erectile dysfunction compounds. We get our raw ingredients from high-quality sources. Our chemicals have independent, third-party Certificates of Analysis for purity identification. Our product page also contains product information that can be useful for research in vivo. If your research is looking for affordable alternatives and individual profound effects? You may opt to consider Mirodenafil and Tadalafil tablets. PureRawz offers other chemicals such as bacteriostatic water, cardarine, melatonin, noopept , semaglutide, and more. This comprises selective androgen receptor modulators (SARMs) available in multiple variants, such as capsules that are similar to the functions of trestolone acetate.

We offer free, fast shipping on orders over $100 in the US and abroad! This makes us the top option for the best Eros (Mirodenafil + Amino Tadalafil + SR-9011 + GW-0742) combined formula near you. It is important to note that our website has age verification. Payment can be made by PayPal or Bitcoin. Click customer reviews to read what people think about our products and great prices.

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