Description
HGH GMP 98% – Product Information
HGH, or human growth hormone, is a chemical produced by the pituitary gland. It spurs growth in children.
Throughout life, HGH regulates fat, muscle, and bone in our bodies. It also impacts metabolism by controlling blood sugar levels. After middle age, HGH levels start declining.
Pure Rawz sells HGH GMP 98% for laboratory and research purposes only. The term ‘GMP’ refers to ‘Good Manufacturing Practices’ that cover all aspects of this research chemical’s manufacturing process, from production to shipping. Our HGH GMP 98% is 98% pure.
HGH GMP 98% | |
CAS Number | 12629-01-5 |
Molar Mass | 22,005 g/mol |
Chemical Structure | C39H60N8O13 |
IUPAC Name | L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-tyrosyl-L-isoleucyl-L-prolyl-L-lysine |
What is HGH (GMP 98%)?
Human growth hormone (HGH) is a naturally produced hormone. It is a 191 amino acid single-chain peptide produced and secreted by the anterior pituitary gland. HGH’s release isn’t continuous – this chemical is released in several ‘bursts’ every three to five hours. [R][R]
Although scientists have known about GH since the 1920s, it was only in the 1960s that HGH therapy was used to treat unusually short kids. The practice was halted a few years later due to reports of contamination before a new source for HGH was approved by the FDA. [R]
Initial research into this hormone determined that HGH is responsible for growth during childhood. However, various studies have highlighted various additional roles, such as potentially regulating body composition, impacting metabolism, and promoting lipolysis, among others. [R]
Recent research indicates that GH treatment may improve cardiac function. GH replacement therapy may also have a role to play in enhancing cognitive function. Additionally, recombinant HGH (rHGH) has been shown to be potentially safe and effective in children with chronic kidney disease. [R][R][R]
PureRawz sells HGH GMP 98% for laboratory and research purposes only.
HGH Vs. rHGH
Recombinant human growth hormone (rHGH) is a synthetic protein with almost identical properties to the naturally occurring human growth hormone (HGH). It is known by many names in the US, including somatotropin, norditropin, nutropin, and more. [R]
HGH GMP 98% vs. HGH 191AA
HGH GMP 98% and HGH 191AA are both forms of human growth hormone (HGH), but they refer to different aspects of the hormone.HGH 191AA refers to the specific sequence of 191 amino acids that make up the hormone. This is the natural form of HGH produced by the human body and is the most commonly used form of HGH in medical treatments
HGH GMP 98% refers to the purity of the HGH. GMP stands for Good Manufacturing Practice, which is a set of guidelines for ensuring the quality and safety of pharmaceutical products. HGH GMP 98% means that the HGH has been manufactured according to these guidelines and is at least 98% pure. So while HGH 191AA refers to the specific amino acid sequence of the hormone, HGH GMP 98% refers to the quality and purity of the HGH product. It’s possible to have HGH that is both 191AA and GMP 98%, but they are not the same thing.
How is rHGH produced?
Recombinant HGH is generally produced in a two-step process. The first step involves inserting the natural HGH gene into the plasmids of E. Coli bacteria. These bacteria then act on the HGH gene to produce HGH hormones, which are then extracted for further use. [R]
Has the FDA approved rHGH use?
The FDA has allowed the clinical use of rHGH in children to treat short stature caused by HGH deficiency. Recombinant HGH has also been approved for adults with GH deficiency. [R] [R]
Is rHGH the same as HGH?
Recombinant HGH is virtually identical to natural HGH, complicating matters for authorities hoping to detect synthetic HGH for enhanced performance. However, the latest research has indicated that differentiation could exist on minor post-translational differences in rHGH. [R]
How does HGH Work?
HGH has two mechanisms of action: direct action and indirect action. The direct effects originate from HGH binding to target cells and stimulating a response. These cells are located throughout the body, including the skeletal muscle, brain, heart, and even kidneys. [R]
The indirect effects occur in response to the action of insulin-like growth factor 1, whose levels are raised by the body in response to enhanced HGH binding to receptors (direct action).
One can better understand HGH’s effects by considering them as combined effects of HGH and IGF-1.
HGH Research
What follows is a summary of existing clinical, animal, and cell-based research on HGH. The information given in this section is for information purposes only. It shouldn’t constitute medical advice on growth hormone and HGH supplements. PureRawz doesn’t sell HGH for human use.
HGH and Lean Muscle Mass
HGH treatment has been shown to potentially increase lean muscle mass in healthy and GH-deficient adults.
A 1996 study set out to investigate the effects of GH treatment on muscle mass, muscle strength, and protein synthesis in healthy subjects over 60 years old. It was found that GH potentially increased the first two parameters but failed to rejuvenate myofibrillar protein synthesis. [R]
Another trial was conducted to demonstrate the potential effects of rHGH treatment in GH-deficient adults. Results from the study indicate a potential increase in lean muscle mass.
Specifically, the study noted significant potential increases in the cross-sectional area of thigh muscles and quadriceps muscles. [R]
HGH and Muscle Strength
A cell-based study has shown how GH could increase muscle strength.
GH has been found to increase muscle strength by potentially enhancing muscle mass without affecting contractile force or fiber composition type. Additionally, it has been shown that GH may stimulate protein accumulation in the entire body while stimulating protein synthesis in muscular sites. [R]
A clinical study evaluated muscle strength in healthy men over 50 years after six months of GH therapy. All patients practiced some kind of exercise at least 3 times per week.
Results showed that the HGH group experienced a potentially significant increase in leg press-responsive muscles. [R]
HGH and Fat Loss
Studies show that GH treatment induces a potential net loss of body fat.
In one study, 12 obese women saw their body fat fall by a potential 2 percent after being treated with GH for 28 days. Their fat-free mass increased by 3.4 kg during the same time period. Based on these results, the authors concluded that GH may induce body fat loss. [R]
A similar body fat loss was observed in GH-deficient adults and the elderly. However, while HGH induces a net loss in body fat, it doesn’t cause weight loss. All three studies that found HGH potentially reducing body fat also concluded that its effect on body weight was close to minimal. [R]
HGH and Osteoporosis
GH could be used as a potential anabolic agent in osteoporosis.
In a study involving eighty postmenopausal women with osteoporosis, the administration of HGH potentially increased bone mineral content, a key measure of bone strength. There was a 14% increase in bone mineral content in the GH group and side effects were rare. [R]
A similar effect was observed in men with idiopathic osteoporosis. A two-year treatment with GH brought about a potential increase in bone mineral density and bone mineral content in the study’s participants. Significantly, the potential increases sustained for one year post-treatment. [R]
HGH and Potential Exercise Capacity
GH may improve anaerobic exercise capacity in GH-deficient subjects.
Research has shown that GH could potentially increase exercise capacity by increasing the delivery that is needed for extensive workouts. These fuels include glucose and fatty acids. Administration of GH has been shown to potentially increase the availability of both these metabolic fuels. [R]
A meta-analysis of multiple studies also found a positive correlation between GH administration and improved exercise performance in GH-deficient patients.
However, in a study involving athletes, GH administration was linked with reduced exercise capacity. [R] [R]
HGH and The Heart
In a three-month study, the effects of GH administration on the heart health of patients suffering from heart failure due to myocardial infarction (MI) were investigated. It was found that GH administrated potentially increased left ventricular ejection function, which is good for heart health. [R]
A pre-clinical study has shown that growth hormone replacement therapy may improve cardiac function. Results from the study indicate that GH potentially increased myocardial contractility (the innate ability of the heart muscle to contract) and decreased peripheral vascular resistance in heart failure. [R]
More studies are needed to investigate the relationship between GH and heart health.
HGH and Cognition
Emerging data indicate that GH may improve cognitive function.
Multiple studies have found that after GH substitution, adult patients with GH deficiency experience potentially improved motivation, emotion, memory, and cognition. Similarly, HGH treatment potentially improved attention, perception, and cognitive capacity in children with GH deficiency. [R]
Another psychological item impaired in patients with GH deficiency is cognitive functioning. For instance, mood disturbances and cognitive impairments are common comorbidities in GHD patients.
Again, on both counts, GH therapy might help. [R]
HGH and Wound Healing
Growth hormone has been shown to accelerate wound healing.
HGH has been shown to potentially stimulate granulation tissue formation, increase collagen deposition, and facilitate epithelialization. Furthermore, it has been demonstrated that the wound-healing effect of HGH isn’t direct. Instead, it’s potentially mediated by the action of IGF-1. [R]
Given its involvement in wound healing, a pre-clinical study was conducted to investigate whether rHGH improves pressure ulcer (PU) healing. Results from this study indicate that the rHGH healing group experienced a potential healing rate twice as fast as the control group. [R]
HGH and Fertility
HGH may be a candidate for male and female fertility.
As part of a clinical trial, nine men with low sperm motility and nine with reduced sperm count were treated with human growth hormone supplements for 12 weeks. The final results show a potential increase in sperm motility in both groups. Additionally, three pregnancies were reported in the first. [R]
In females, GH therapy is one of the adjuvant treatments used in ovarian stimulation. It has been shown that growth hormone impacts ovarian function and the female reproductive system, increasing the possibility of GH replacement therapy to enhance female fertility. [R]
Frequently Asked Questions
Is HGH a steroid?
Although it’s often lumped with steroids, HGH is a chemical produced naturally in the human body. It is secreted and released by somatotropic cells in the anterior pituitary.
Does HGH increase testosterone?
In an animal study, HGH directly stimulated testosterone and estradiol secretion. While anecdotal evidence claims a similar relationship also exists in humans, long-term clinical trials are needed to investigate whether any such correlation exists. [R]
Does HGH burn fat?
In a clinical study, twice-daily administration of HGH-releasing hormone (GHRH) stimulated growth hormone production and potentially decreased abdominal visceral fat in postmenopausal subjects. [R]
Does HGH aid erectile dysfunction?
Data from a clinical study involving healthy subjects and erectile dysfunction (ED) patients indicates that GH may be potential of major importance in maintaining male erectile capability. [R]
Does HGH enlarge the prostate?
Results from a human study indicate that GH replacement potentially restores prostate size to normal. The study involved young and elderly patients with growth hormone deficiency. No increase in prostate abnormalities was reported after treatment with synthetic HGH injections. [R]
Where to Buy HGH?
PureRawz is the best place to buy HGH online.
In order to be the best supplier of research peptides, we provide reference materials with every product we sell. All of our products come with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.
We offer free international shipping on all orders above $100. You can pay for your purchase through various methods, including PayPal and Bitcoin. We sell HGH injections/vials.
HGH Summary
Human growth hormones (HGH) is a 191 amino acids peptide capable of potentially stimulating lean muscle mass growth, improving bone mineral density, and expediting wound healing. Pure Rawz sells HGH (GMP 98%) for research and laboratory purposes only.
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