Honokiol (Magnolia Bark Extract) 98%

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Honokiol (Magnolia Bark Extract) 98% (Powder) – Product Information

Herbal extracts, such as magnolol and honokiol derived from Magnolia bark, have been studied for their potential health benefits and have gained significant attention in the world of natural medicine. With its rich history in traditional Chinese medicine, this natural substance has captured the interest of researchers for its potential health benefits.

The information provided in this article, along with any subsequent research findings related to honokiol magnolia bark extract, is intended for educational and research purposes only. It should not be construed as human consumption, medical advice, or a recommendation for self-treatment.

Honokiol (Magnolia Bark Extract) 98%
CAS Number 35354-74-6
Molar Mass 266.334 g/mol
Chemical Formula C18H18O2
IUPAC Name 3′,5-Di(prop-2-en-1-yl)[1,1′-biphenyl]-2,4′-diol


What is Honokiol Magnolia Bark Extract?

Honokiol magnolia bark extract is derived from the bark of the magnolia tree, particularly from the species Magnolia officinalis and Magnolia plants grandiflora is common in Southeast Asia like. Honokiol is a biphenolic compound that serves as one of the key active constituents within the extract. It is characterized by its polyphenolic structure and exhibits various pharmacological properties. (R)

How Does Honokiol Magnolia Bark Extract Work?

Honokiol Magnolia Officinalis bark extract potentially works through multiple mechanisms. It may have the potential to interact with the GABA receptors in the brain, potentially promoting relaxation and reducing anxiety. (R)

It may also inhibit inflammatory pathways, suppressing inflammation in the body, and exhibits potential potent antioxidant activity, protecting cells from oxidative damage. (R)

Honokiol may also potentially modulate signaling pathways involved in cell growth and survival. It has the potential to interact with various receptors and enzymes, contributing to its overall effects. (R)

When considering the potential developmental toxicity of honokiol bark extract additional research is required to gain a comprehensive understanding of its mechanisms and to ascertain its efficacy and safety in specific applications.

Honokiol Magnolia Bark Extract Research

Honokiol as one of the active ingredients in magnolia bark extract has been traditionally used in East Asian cultures for centuries and has recently gained attention in scientific research for its potential health benefits. While further studies are needed to fully understand its efficacy and safety, the following applications that support clinical research: (R)

Relief from Anxiety and Stress

While animal studies have shown promising results regarding honokiol extract’s anxiolytic effects, clinical studies on subjects are necessary to validate these findings. One clinical trial conducted on subjects with preoperative anxiety found that a single dose of honokiol significantly reduced anxiety levels compared to a placebo group. (R) (R)

Preclinical studies have indicated that honokiol exhibits neuroprotective potential. Studies with animals have shown that honokiol can protect neurons from oxidative stress, reduce brain inflammation, and may promote healthy sleep. (R)

Furthermore, a clinical study involving patients with Alzheimer’s disease suggested that honokiol may improve cognitive function, specifically memory, and attention.

Anti-Inflammatory and Antioxidant Activity

Honokiol has demonstrated anti-inflammatory properties by inhibiting specific inflammatory pathways in preclinical studies. In a clinical trial involving patients with inflammatory bowel disease, honokiol reduced disease activity and potentially improved symptoms compared to a placebo group. (R)

Moreover, honokiol’s potent antioxidant activity has been observed in several studies, protecting against oxidative damage in both animal and cell models.

Cancer Research

Laboratory studies have demonstrated the anticancer effects of honokiol by inhibiting the growth of cancer cells and inducing apoptosis. While clinical trials evaluating the direct anticancer effects of honokiol in humans are limited, some studies have explored its potential as an adjunctive therapy.

For instance, a clinical trial investigating the use of honokiol alongside chemotherapy in patients with advanced pancreatic cancer reported enhanced anticancer activity and improved overall survival.

However, further clinical trials are needed to fully assess the efficacy, safety, and potential applications of honokiol in cancer treatment. (R) (R) (R)

Frequently Asked Questions (FAQs)

What are the potential health benefits of Honokiol Magnolia Bark Extract?

Honokiol magnolia bark extract has shown potential for anxiety relief, neuroprotection, anti-inflammatory effects, and potential anticancer properties. (R)

How does Honokiol Magnolia Bark Extract work?

Honokiol magnolia bark extract works through various mechanisms, including potential interaction with neurotransmitter systems, regulation of inflammatory pathways, antioxidant activity, and modulation of signaling pathways. These mechanisms contribute to its potential health effects.

What further research is needed on Honokiol Magnolia Bark Extract?

Further research is necessary to fully understand the mechanisms of action of honokiol magnolia bark extract and validate its potential health benefits in humans. Rigorous clinical trials are needed to determine its efficacy, optimal dosage, long-term safety, and potential interactions with medications or other supplements.

Are there any regulatory bodies that oversee the quality of Honokiol Magnolia Bark Extract?

In the United States, the FDA regulates dietary supplements, including Honokiol magnolia bark extract, under the Dietary Supplement Health and Education Act (DSHEA). The FDA ensures compliance with labeling requirements and Good Manufacturing Practices (GMP) for supplement manufacturers. Other countries may have their regulatory bodies overseeing Honokiol Bark Extract with other ingredients as marketed dietary supplements and cosmetic products.

What is the shelf life of Honokiol Magnolia Bark Extract?

The Honokiol Magnolia bark extract’s shelf life might vary based on several elements, including the manufacturing procedure, the storage environment, and the inclusion of any stabilizers or preservatives.


A natural substance and active ingredient called honokiol magnolia bark extract is obtained from the magnolia species. It demonstrates a range of possible health advantages, including the reduction of anxiety, neuroprotection, anti-inflammatory actions, and possibly anticancer capabilities. The extract functions in a variety of ways, including by influencing neurotransmitter systems, controlling inflammatory pathways, exhibiting antioxidant activity, and altering communication pathways.

Where to buy Honokiol Magnolia Bark Extract 98%?

Pure Rawz is the best place to buy Honokiol Magnolia Bark Extract 98% on the online website.

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This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).
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6 reviews for Honokiol (Magnolia Bark Extract) 98%

  1. Samuel Lewis

    The most concentrated form of honokiol and most effective I’ve seen on the market!

  2. Martin Elders

    I finally found the Magnolia Bark that works. You guys are the real deal

  3. JJ

    Despite the fact that I have yet to use the products, customer service was excellent, and international shipping was quick.

  4. Jeremy Roberts

    I started taking these, and they absolutely make a difference in putting me at ease and helping with feeling so overwhelmed.

  5. Corey Ryan

    This has really been helping for my anxiety and back pain, I will need to order more soon.

  6. Fred Reyes

    The inflammation I have had in my shoulder is finally going down.

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