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L-Carnosine – Product Information

L-Carnosine, or carnosine, is an endogenous (occurring naturally) di-peptide made up of one molecule of histidine and one alanine molecule. According to available research studies, this product is a potent antioxidant that speeds up wound healing and encourages the chelation of heavy metals.

L-Carnosine is also believed to buffer lactic acid in muscle tissue, which explains why it may improve physical performance by affecting skeletal muscle tissue when engaging in demanding activities (e.g., weight lifting, sprinting, etc.).

Today, l-carnosine is being studied as a potential dietary supplement, commonly available as L-carnosine 500mg. Some brands offer gluten-free l-carnosine to cater for a vegan class of consumers.

Although l-carnosine may promote certain health advantages, it is still a researched chemical compound. The chemical is not intended to diagnose, treat, cure, or prevent illnesses. To rely solely on it for nutrition or medication is inadvisable.

Purerawz sells L-carnosine for research purposes only.

CAS Number 305-84-05
Molar Mass 226.3 g/mol
Chemical Formula C9H14N4O3
IUPAC Name (2S)-2-(3-Aminopropanamido)-3-(3H-imidazol-4-yl)propanoic acid

What is L-Carnosine?

Carnosine’s scientific name is beta-alanyl-L-histidine. It is made up of two amino acids, histidine, and beta-alanine. Carnosine’s L form, or isomer, is biologically active in humans.

L-Carnosine is a substance that is present in large amounts in the body’s brain and muscle tissues, but levels fall off significantly as we get older.

According to neurological studies, L-carnosine appears to boost brain activity in brain regions responsible for emotion, abstract thought, and expressive speech. Additional studies have revealed that L-carnosine has antioxidant, neurotransmitter, detoxification support, and cell protection and repair properties.

Possible Applications of L-Carnosine

L-Carnosine and Muscle Function

Carnosine could act as an acid buffer and assist in muscle vitality alongside maintaining proper function. [R]

Carnosine concentrations in the muscles are reduced when it is high. Carnosine improves muscle elasticity and delays or prevents muscle fatigue, by protecting against lactic acid buildup. [R]

Muscle carnosine loading improves high-intensity exercise performance in both untrained and trained individuals. Although carnosine is not involved in the classic adenosine triphosphate-generating metabolic pathways, this suggests that the dipeptide plays an important role in contracting muscle cell homeostasis, particularly during high rates of anaerobic energy delivery. [R]

However, more studies are needed to verify this effect of carnosine.

L-Carnosine and Alzheimer’s Disease

Carnosine dietary supplements could potentially be therapeutic in Alzheimer’s and Parkinson’s disease. Based on a certain study, carnosine treatment (1.5g/d -alanine) improved a number of neurological symptoms in these neurological disorders. [R]

Nevertheless, carnosine is not a recommended treatment for Alzheimer’s disease.

L-Carnosine and Oxidative Stress

Carnosine is an excellent antioxidant. Research shows it can significantly reduce the cellular damage caused by highly reactive oxygen free radicals produced by the uncontrolled oxidation of lipids and sugar, which can occur in metabolic syndrome and diabetes. [R]

L-Carnosine and Diabetes

Carnosine may be especially beneficial to diabetics because it can protect against protein glycation damage. This process, which occurs when the body has too much sugar, is a major contributor to diabetes-related complications such as kidney and nerve damage. [R]

Although research is still in its early stages, animal and human studies have shown that supplementing with carnosine (which is depleted in both animals and humans with type 2 diabetes) can delay the progression of diabetes and prevent such complications. [R]

L-Carnosine and Cancer

Several preliminary (cell culture) studies suggest that carnosine may be helpful in the fight against cancer. Carnosine, for example, inhibited the growth of many significant types of cancer cells, including liver, colon, and ovarian cells. [R]

There is also evidence from studies that link low carnosine levels or high activity of carnosidase, the enzyme that breaks down carnosine, to a poor cancer prognosis. [R]

Still, the research chemical requires in-depth clinical trials to determine its effects against cancer.

How Does L-Carnosine Work?

Carnosine is essential for many normal body functions, including muscle and development, as well as the proper function and development of the heart, liver, kidneys, brain, and many other organs. Carnosine may help prevent aging because it appears to interfere with certain chemicals that may play a role in aging.

The muscle cells play one of the most distinctive jobs for carnosine. It serves as a buffer to keep the muscle functioning stable. Fatigue develops as acidity increases and the pH of the muscle drops. Creating cross-connections between proteins is essential for power production, and the shortening of the muscle fibers might become impaired. Carnosine prevents that pH drop and aids in maintaining healthy muscular function.

Frequently Asked Questions

Does the human body possess L-carnosine?

Muscle tissue has the most significant levels of carnosine in the human body. Yet, there are also relatively high concentrations in brain tissue. The naturally occurring peptide may also be found among innervated tissues.

What does L-carnosine do to the brain of subjects?

L-carnosine reduced aging-induced increases in mitochondrial monoamine oxidase-A activity in the brain. Furthermore, L-carnosine protects neurons by modulating the HO-1/Hsp72 system and reducing neuronal damage caused by oxidative stress. [R]

What foods contain L-carnosine?

Meats, such as turkey, chicken, beef, or pork, are excellent natural sources of carnosine. Carnosine is naturally found in other animal products, such as eggs, milk, and cheese, but only in trace amounts. Because carnosine is found in muscle, the higher the concentration of carnosine, the stronger the muscle.

There is no vegetable source for l-carnosine.

Can you stack L-carnosine?

L-carnosine could work well with CDP choline.

Where can you buy L-carnosine?

PureRawz is the best place to buy l-carnosine online.

In order to be the best supplier of research peptides, we provide reference materials with every product we sell to our customers. All of our products come with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).
Our content is intended to be used and must be used for informational purposes only. It is very important to do your own analysis and research from Trusted Sources before making any purchase, based on your own personal circumstances. You should independently research and verify any information that you find on our Website and wish to rely upon.
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ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human usage.

2 reviews for L-Carnosine

  1. Samuel Kaplan

    I got it after a brief wait. I appreciate the fantastic customer service you provided.

  2. Aaron Musselman (verified owner)

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