Description
Lipopeptide – Product Information
A lipopeptide describes a particular molecule consisting of a lipid connected to a peptide. [R]
Lipopeptides are a structurally diverse class of metabolites produced by various bacterial and fungal genera. Lipopeptide research has been fueled in recent decades by its antimicrobial, antitumor, immunosuppressive, and surfactant properties. Today, the synthetic lipopeptide is produced due to its potential benefits, such as it could help to achieve a more robust immune response and may enhance new collagen production.
Despite the supposed health advantages, polypeptides are still not considered safe for human consumption. We encourage our customers to buy this compound for research purposes only.
Lyophilized peptide powders above 50mg may require more than the regular amount of bacteriostatic water for complete dissolution. Insufficient bacteriostatic water volume may lead to some powder remaining undissolved.
Lipopeptide | |
CAS Number | 103060-53-3 |
Molar Mass | 994.3 g/mol |
Chemical Formula | C50H87N7O13 |
IUPAC Name | 3-[(3S,6S,9S,12S,15S,18S,21S)-9-(carboxymethyl)-25-(7-methyloctyl)-3,6,15,18-tetrakis(2-methylpropyl)-2,5,8,11,14,17,20,23-octaoxo-12-propan-2-yl-1-oxa-4,7,10,13,16,19,22-heptazacyclopentacos-21-yl]propanoic acid |
What is Lipopeptide?
Lipopeptides are made up of a fatty acid (C12-C18) linked to a peptide chain (from 4 to 12 amino acids).
If they are cyclic lipopeptides, they will have a linear hydrophilic head or a lactone ring.
Microorganisms (soil bacteria and fungi) produce lipopeptides as part of their metabolic process.
Lipopeptides are believed to be antibiotic, antifungal, and antitumor agents. They can self-assemble into various structures and comprise a lipid attached to a peptide (short chains of amino acids linked by peptide bonds).
Polypeptides can put themselves together to form various structures. [R]
Numerous bacteria, particularly those belonging to the genera Bacillus, Pseudomonas, and Streptomyces, produced these molecules as part of their metabolism. [R]
A group of lipopeptides is studied for being used as antibiotics. [R]
Specific lipopeptides function as agonists of toll-like receptors. [R]
Some lipopeptides have potent hemolytic and antifungal properties. [R]
It has been shown that interactions with the plasma membrane are generally linked to lipopeptides activity, and the plasma membrane’s sterol components may play a significant role in this interaction.
Potential Applications of Lipopeptides
In general, different bacterial species produce three types of lipopeptides: Surfactin, Iturin, and Fengycin. Each type is given separate tags in a laboratory setting because each is being investigated for potential applications and mechanisms of action.
Lipopeptides in Cosmetics
Lipopeptide has been shown in scientific studies to increase the production of new collagen and hyaluronic acid in existing skin. [R]
It helps to increase one’s natural collagen and HA productivity levels and is regarded as one of nature’s most powerful anti-agers by interacting with cell membranes to boost and revitalize the natural function of the cells and renew them to obtain maximum growth potential.
Lipopeptides, unlike water-soluble peptides, are highly biocompatible with the skin’s natural structure.
Lipopeptide Surfactin as Antimycoplasma Agent
Surfactants have a wide range of bioactive properties, including anti-mycoplasma activity, as suggested by various studies. [R] [R] [R]
Mycoplasma is the smallest free-living organism and eukaryotic cell parasite, and it is one of the most common contaminants in mammalian tissue culture cells. Surfactin’s low cytotoxicity for mammalian cells enables the targeted inactivation of mycoplasmas with minimal negative effects on cell metabolism and proliferation in culture.
Lipopeptide Surfactin as AntiparasiticAgent
A particular study demonstrates lipopeptide’s capability to deal with certain parasites.
Surfactin showed potential as an alternative nosemosis treatment for bees. The spores of Nosema ceranae, the causative agent of parasitic infection among Western Honey Bees (Apis mellifera), showed a significant reduction in infectivity when exposed to Surfactin. [R]
Lipopeptide as Antiviral
Surfactin has a potent antiviral effect and has been shown by a team of researchers to be a membrane fusion inhibitor. Viral fusion is less likely when surfactin is inserted into the lipids of the viral envelope. [R]
How Does Lipopeptide Work?
It is possible to study lipopeptides for their biomedical and pharmaceutical uses as antimicrobial, anti mycoplasma, antiadhesive, and antitumor agents because of their behavior as biosurfactants.
These Bacillus species-derived biosurfactants are well-known for being the best microbial surfactants.
Lipopeptide surfactants are also thought to be safe for the environment.
The study of lipopeptide biosurfactant effects on human and animal cell lines has gained more and more attention.
The biosurfactants under consideration play various roles, including acting as pathogen-repelling agents, making them valuable as pharmaceutical, probiotic, and therapeutic agents.
Frequently Asked Questions
Are lipopeptides safe?
The safety of lipopeptides for human usage is still being studied. Due to this fact, purchase this research compound for the purpose of laboratory-controlled experiments.
Do lipopeptides affect the skin’s natural structure in research subjects?
Researchers found that a particular lipopeptide stimulates collagen production in human skin and corneal cells in a concentration-dependent manner in a 2013 study, suggesting a link between self-assembly and collagen synthesis. Such a conclusion might clarify how lipopeptides affect the structure of the skin. [R]
What other research chemicals have similar functions as lipopeptides?
In terms of their anti-aging property, lipopeptides may be similar to reduced glutathione.
Where can you buy lipopeptides?
PureRawz is the perfect place to buy high-quality lipopeptides online.
We provide reference materials with every product we sell to be the best supplier of research chemicals. Our products are all accompanied by an independent, third-party Certificate of Analysis for identification, purity, and concentration.
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