Pyrroloquinoline Quinone (PQQ)

Description

Pyrroloquinoline Quinone (PQQ) – Product Information

PQQ (pyrroloquinoline quinone), also known as methoxatin or PQQ, is a vitamin-like molecule found naturally in soil. It is also present in certain foods such as green tea, spinach, kiwi, soybeans, and human breast milk. [R]

PQQ supplements are believed to improve energy, memory, and focus. PQQ is also thought to influence overall cognitive health. This naturally occurring compound may also provide sleep quality support. However, researchers are still unsure how these supplements affect human health holistically.

Despite the alleged positive benefits of pyrroloquinoline quinone for sale bring, its dietary supplements are inadvisable for human consumption. PQQ cannot be utilized as a treatment for a known disease or health condition. We recommend buying this experimental chemical for research purposes only.

Pure Rawz sells pyrroloquinoline quinone in 25mg tablets. Certain brands offer non-GMO, gluten-free pyrroloquinoline quinone for sale with other ingredients such as magnesium stearate and vitamin C.

What is Pyrroloquinoline Quinone?

Pyrroloquinoline quinone (PQQ) is a small quinone molecule. It is also known as methoxatin, pyrroloquinoline quinone disodium salt, and a longevity dietary supplement.

It can be a REDOX agent, capable of reducing oxidants (an antioxidant activity) and then being recycled back into an active form by glutathione.

It appears to be quite stable because it can go through several thousand cycles before being depleted, and it is novel because it associates with protein structures inside the cell.

PQQ pyrroloquinoline quinone supplementation has become well-known due to its purported ability to be an energy optimizer. PQQ could also address mitochondrial functions, converting nutrients into energy cells can use.

There is also evidence that PQQ may benefit cognitive support and cardiovascular health.

Potential Applications of Pyrroloquinoline Quinone

Pyrroloquinoline Quinone and Cardiovascular Support

In rat models of ischemia and ischemia/reperfusion, PQQ given as a pretreatment or as treatment at the onset of reperfusion is highly effective in reducing infarct size and improving cardiac function in a dose-related manner using 15mg/kg as optimal dosage. [R]

According to this clinical trial, PQQ appears to act as a free radical scavenger in ischemic myocardium and is a highly effective cardioprotective agent. [R]

Regardless of the above-mentioned positive results, more studies are needed to determine if pyrroloquinoline quinone promotes a healthy cardiovascular system.

Pyrroloquinoline Quinone and Cognitive Function

PQQ has been shown to demonstrate neuroprotective properties. This research chemical formula is thought to protect specific rodent models against Parkinson’s disease.

In vitro studies suggest that this protective effect is achieved by reducing oxidative stress and protecting cellular mitochondria, thereby suppressing cell death which affects brain health. [R] [R]

More research is needed to determine PQQ’s effects on Parkinson’s disease in humans.

Pyrroloquinoline Quinone and Bone Health

PQQ appears to improve the negative feedback mechanism controlling osteoclastogenesis (the production of osteoclasts, which are negative regulators of bone mass), and this improves overall osteoclast activity, which is thought to promote bone mass over time.

PQQ for sale has the potential to play a similar role in preventing osteoporosis by reducing oxidative stress and osteoclastic bone resorption. [R]

Even though the experimental chemical could potentially give human bones improved health, PQQ still needs more laboratory-controlled experiments.

How does Pyrroloquinoline Quinone Work?

In animal models and cultured cells, the mechanism of action involves the activation or expression of factors such as peroxisome proliferator-activated receptor alpha; cAMP response element-binding; nuclear respiratory factors 1 and 2; transcription factor A, mitochondrial; and peroxisome proliferator-activated receptor-coactivator 1-alpha. [R]

Each of these transcription factors and coactivators is involved in the regulation of cellular energy metabolism and mitochondrial biogenesis, as well as the remodeling of muscle tissue to a fiber-type composition that is more oxidative and less glycolytic. [R]

Furthermore, genes involved in cellular stress, cell signaling, and nutrient transport are affected, implying that PQQ may first act via cell surface cytokine and growth factor receptors or by influencing the phosphorylation of key components. [R]

Frequently Asked Questions

Could Pyrroloquinoline Quinone Occur Naturally?

It can be found in a variety of foods, including fermented soybeans, natto, green peppers, kiwi, parsley, tea, papaya, spinach, and celery.

Is Pyrroloquinoline Quinone better than CoQ10?

PQQ has one important action that involves direct action on key enzymes involved in energy production within the mitochondria. It functions in conjunction with coenzyme Q10, a well-known compound that is also essential for mitochondrial function.

PQQ pyrroloquinoline quinone is more critical than CoQ10 because human cells can produce CoQ10 but cannot produce PQQ. To meet the PQQ requirements, humans may rely on safe dietary intake or approved supplementation.

CoQ10 functions as a spark plug in energy production, whereas PQQ functions differently. It works in conjunction with CoQ10 to produce energy. It also protects the mitochondria from oxidative damage and promotes mitochondrial biogenesis, the spontaneous generation of new mitochondria within aging cells.

What is pyrroloquinoline quinone good for?

PQQ could be studied to potentially provide several benefits for the brain and body, such as stimulating mitochondrial biogenesis, producing nerve growth factors, providing powerful antioxidant activity, reducing inflammation, and reducing oxidative stress.

However, these positive effects do not suggest that PQQ is a safe chemical that promotes healthy well-being among humans. Further research studies are still ongoing for PQQ’s supposed health benefits.

Where can you buy Pyrroloquinoline Quinone?

Pure Rawz is the best place to buy the highest-quality pyrroloquinoline quinone online.

In order to be the best supplier of research chemicals, we provide reference materials with every product we sell. All of our products come with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.

We offer free international shipping on all orders above $100. You can pay for your purchase through various methods, including PayPal and Bitcoin. We sell liquid, powder, and capsule high-quality TUDA formulations. All the formulations are equally high-quality.