Reduced Glutathione (Vial) – Product Details
Glutathione is an essential component of the antioxidant system, which safeguards the body against free radicals at the cellular level. This hormone could be the most abundant intracellular thiol among animal living cells.
Reduced glutathione participates in the synthesis and repair of DNA, as well as the antioxidant activity of vitamin C, amino acid transport, and the detoxification of harmful compounds.
Reduced glutathione is being studied as a potential dietary supplement that could positively affect the human body based on its antioxidant functions aside from promoting skin health. However, this chemical compound is not intended to diagnose, treat, cure, or prevent illnesses.
Adverse reactions occur during the misuse of this experimental drug. Reduced glutathione supplements are not recommended for human consumption.
Reduced Glutathione Peptide | |
CAS Number | 70-18-8 |
Molar Mass | 307.32 g·mol−1 |
Chemical Formula | C10H17N3O6S |
IUPAC Name | (2S)-2-Amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]carbamoyl}butanoic acid |
What is Reduced Glutathione?
Glutathione is a tripeptide (or small protein) with intracellular low molecular weight made up of three amino acids: cysteine, glycine, and glutamic acid (or glutamate). Glutathione, also known as a powerful antioxidant, increases the utilization and recycling of other antioxidants such as vitamins C and E, alpha-lipoic acid, and CoQ10.
Glutathione comes in two forms: reduced glutathione (GSH, or L-glutathione), which is active, and oxidized glutathione (GSSG), which is inactive.
DNA creation and repair depend heavily on reduced glutathione. Additionally, it improves the transport of amino acids, vitamin C’s antioxidant activity, and toxic substances’ detoxification. [R]
Reduced glutathione becomes oxidized and inactive as it patrols the cellular environment and extinguishes oxidative “free radical” fires, transforming into oxidized glutathione.
Fortunately, the glutathione reductase enzyme can recycle inactive GSSG into active GSH.
When this enzyme is overworked, and a large amount of oxidized GSSG accumulates (compared to active GSH), your cells become vulnerable to damage.
Possible Applications of Reduced Glutathione
Reduced Glutathione and Diabetes
Long-term high blood sugar levels are associated with low glutathione levels. This results in oxidative stress and tissue damage. [R]
A study discovered that consuming cysteine and glycine supplements increased glutathione levels. It also reduces oxidative stress and damage in people with uncontrolled diabetes, despite high blood sugar levels. [R]
Reduced Glutathione and Liver Health
Protein, enzyme, and bilirubin levels in the blood of people with alcoholic and nonalcoholic chronic fatty liver disease have been demonstrated to be improved by glutathione.
According to a study, intravenous administration of high doses of glutathione to patients with fatty liver disease had the best results. Malondialdehyde, a measure of liver cell damage, also decreased in research participants. [R]
Reduced Glutathione and Respiratory Disease Symptoms
Asthma and cystic fibrosis are two illnesses that can be treated with N-acetylcysteine. It aids in thinning mucus and making it less paste-like when inhaled. It lessens inflammation as well. Reduced glutathione supplement could produce N-acetylcysteine as a byproduct. [R]
But further research is still needed to verify this assertion.
Reduced Glutathione and Peripheral Disease
Peripheral artery disease occurs when the arteries in the legs become clogged by plaque. [R]
One study found that glutathione improved circulation, allowing participants to walk pain-free for longer distances. [R]
Reduced Glutathione and Oxidative Stress
Oxidative stress occurs when there is an imbalance between the production of free radicals and the body’s ability to combat them. Excessive oxidative stress may be a precursor to a variety of diseases. [R]
Diabetes, cancer, and rheumatoid arthritis are examples. Glutathione helps mitigate oxidative stress’s effects, which may lead to a reduction in disease. [R]
According to one article, glutathione deficiency causes increased levels of oxidative stress, which may lead to cancer. [R]
It was also stated that increased glutathione levels increased antioxidant levels and oxidative stress resistance in cancer cells. [R]
Reduced Glutathione and Insulin Resistance
A team of researchers investigated the function of glutathione in aging-related insulin resistance and weight management using a combination of animal and human studies. [R]
When cysteine and glycine were added to the diets of older participants, their levels of reduced glutathione purportedly increased within two weeks, which improved their insulin resistance and fat burning.
Reduced Glutathione and Autoimmune Disease
Based on a clinical study, glutathione either increases or decreases the body’s immune response, which helps alleviate oxidative stress. [R]
Diseases with an autoimmune component damage particular cells’ mitochondria. By scavenging free radicals, glutathione protects the mitochondria of the cell.
How Does Reduced Glutathione Work?
Reduced glutathione is involved in both xenobiotic and endogenous compound detoxification. It promotes cell excretion, body excretion and directly neutralizes many oxidative chemicals. [R]
Glutathione aids in the transport of toxins across the plasma membrane via at least four different mechanisms, the most important of which is the formation of glutathione S-conjugates. [R]
Chronic exposure to chemical toxins and alcohol, cadmium exposure, AIDS/HIV, macular degeneration, Parkinson’s disease, and other neurodegenerative disorders are all linked to low glutathione and transferase activity. [R]
Glutathione scavenges various oxidants, including superoxide anion, hydroxyl radicals, nitric oxide, and carbon radicals. Glutathione detoxifies hydroperoxides, peroxynitrites, and lipid peroxides catalytically. [R]
Another way glutathione protects cells from oxidants is by recycling vitamins such as vitamin C and E. [R]
Safety and Side Effects
Although reduced glutathione could offer supposed health benefits, this research chemical is not risk-free. The following are some possible side effects:
- Stomach cramps
- Bloating
- Breathing difficulties caused by bronchial constriction
- Allergic reactions
For this reason, individuals who mistakenly ingested reduced glutathione and have exhibited the side effects mentioned above should seek help from a qualified healthcare professional.
Frequently Asked Questions
Is reduced glutathione different than glutathione?
The distinction between reduced glutathione and glutathione is minimal. However, there are two different types of glutathione: oxidized glutathione (GSSG), which is inactive, and reduced glutathione (GSH, or L-glutathione), which is the active form.
How is reduced glutathione available?
Reduced glutathione is typically available in the form of capsules and powder. It is also manufactured using other ingredients, such as magnesium stearate, silicon dioxide, and microcrystalline cellulose. Other brands sell non-GMO reduced glutathione to cater to a vegetarian clientele.
Is reduced glutathione safe?
Reduced glutathione may offer certain health benefits, but this experimental drug is not a recommended food supplement. Further research is needed to determine the conclusive medical effects of reduced glutathione.
What can you stack with reduced glutathione?
Reduced glutathione could work well with L-carnitine. As supported by a specific study, the combination of the two has been demonstrated to protect the plasma membrane in case of oxidative damage, resulting in improved sperm morphology and mobility. [R]
Where can you buy reduced glutathione?
Pure Rawz is the best place to buy the highest-quality reduced glutathione online.
In order to be the best supplier of research chemicals, we provide reference materials with every product we sell. All of our products come with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.
We offer free international shipping on all orders above $100. You can pay for your purchase through various methods, including PayPal and Bitcoin. We sell liquid, powder, and capsule high-quality TUDA formulations. All the formulations are equally high-quality.
gordan –
Feeling younger and have more energy on this.
Nicholas Roel –
Chris B –
Jennifer Andy –
Not sure if this could be it but my skin tone has improved a lot after using this.
Bryan Bolo (store manager) –
I’ve been using Reduced Glutathione as an overall antioxidant for a couple of years.. Excellent product!
Freddie –
I’ve been using Reduced Glutathione as an overall antioxidant for a couple of years. Excellent product!
Anonymous –
I love the result. My skin looks brighter.
Woodrow Harrington –
This is an amazing product that helps me with my immune system, my skin and it does relieve my joint swelling. I would highly recommend this product!
Fausto L –
Very legit and effective! I can’t wait for my next order to arrive. 🙂
Josh Gregory –
This is affordable compared with other brands.
Bob C –
Anonymous –
It is working perfectly fine for me. I feel better and stronger in and outside the gym
Craig –
James White –
Absorbs well, the price is a plus for this product.
Jason –
Arnold Johns –
I have been a purerawz customer for a year and a half and have found them reliable, consistent, responsive, and quality conscious. They go about their business in a very professional manner and their Reduced Glutathione are top shelf. I am glad I found this company.
Daniel Wilson –
For reduced stress, go for this one!