Protirelin (TRH Thyrotropin)

Description

What is Protirelin (TRH Thyrotropin)?

Protirelin (TRH, Thyrotropin-Releasing Hormone) is a tripeptide hormone produced in the hypothalamus. It may play a key role in controlling the release of TSH from the anterior pituitary.

Researchers study Protirelin for its potential effects on several areas. These include HPT axis, CNS activity, neuroprotection, and mood regulation.

It is not approved for human or veterinary use.

Chemical Properties

IUPAC Name	H-Pyr-His-Pro-NH2
Synonyms	Thyroliberin, Lopremone, Synthetic TRH
CAS Number	24305-27-9
Molecular Formula	C16H22N6O4
Molecular Weight	362.38 g/mol
AppearanceÂ	Sterile Filtered White Lyophilized (freeze-dried) powder
Purity	≥98.2%
Storage	-18°C

How does Protirelin work?

Protirelin may bind to TRH receptors (TRHR), which are primarily located in the pituitary and select brain regions.

This binding may trigger the release of thyroid-stimulating hormone. It may also activate downstream intracellular signaling pathways.

Possible mechanisms include:

• Stimulation of the phospholipase C (PLC) pathway
• Increase in levels of inositol trisphosphate (IP3) and diacylglycerol (DAG)
• Enhancement of calcium ion influx and hormonal secretion

Researchers have observed these mechanisms in preclinical and in vitro models.

What are the potential benefits of Protirelin?

Current scientific studies suggest the following research applications for Protirelin:

• Protirelin may help researchers investigate thyroid disorders in research models.
  
• TRH may help protect the brain in research models. It could be useful in cases of brain injury and neurodegenerative diseases.
  
• Some studies explore its role in improving alertness, memory, and cognitive function.
  
• Protirelin may be a candidate for depression-related research due to its CNS activity.
  
• Researchers may use it to investigate Protirelin secretion and pituitary function in research subjects.

NOTE: This product is meant for research purposes only. It is not approved for human or veterinary use.

Research on Protirelin

Researchers are investigating Protirelin for its various potential benefits. Researchers are studying it for its broader effects on the central nervous system. It may include arousal, seizure control, and behavioral changes in the preclinical model.

Preclinical studies suggest it may influence neurotransmitter systems, including dopamine and serotonin pathways.

Research also studies its role in brain health. It may help reduce damage to brain cells in clinical settings. It might also support recovery in nervous system disorders in clinical settings.

What is the best place to buy Protirelin online for research purposes?

If you want to buy Protirelin for research, PureRawz is a trustworthy supplier.

Each purchase includes a reference-grade Certificate of Analysis. This shows the peptide’s identity, purity, and concentration for research compliance.

Is Protirelin legal?

Protirelin may be legal for research purposes in some regions. Users must comply with local laws and institutional policies.

FAQs

Is Protirelin safe for human consumption?

The FDA has not approved Protirelin for human or veterinary use. Researchers should strictly use it for research purposes.

What are the side effects of Protirelin?

Since Protirelin is a research product, it is still under investigation. Researchers have not yet identified its possible side effects. Further studies are required to confirm these facts.

What is the shelf life of Protirelin?

You can typically store Protirelin for 24 months in a cool, dry place. Proper storage conditions help maintain stability and potency.

How should Protirelin be stored?

It is best to store this product in a cool, dry place away from direct sunlight. This helps extend its shelf life.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY. They are not intended for human or veterinary use.