Description

Orexin B – Product Information

What is Orexin B?

Orexin B, also known as Hypocretin-2, is a naturally occurring neuropeptide. It is synthesized in the hypothalamus, a region of the brain responsible for body functions. Orexin B is one of the two related peptides – the other is Orexin A. 

It may help regulate wakefulness, sleep, appetite, energy balance, and arousal in the brain. This peptide is strictly intended for research purposes and is not approved for human use. 

Chemical Properties

Product Name	Orexin B
Synonym	Orexin, Hypocretin, Hcrt Hypocretin-2
SequenceÂ	H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
CAS Number	205640-91-1
Molecular Formula	C123H212N44O35S
Molecular WeightÂ	2899.34 g/mol
Form	PowderÂ
PurityÂ	≥95%
StorageÂ	-20℃

How does Orexin B work?

Orexin B may work by attaching to a specific receptor in the brain known as Orexin Receptor Type 2 (OX2R). When it binds to this receptor, it may initiate a signal transduction pathway that influences various brain functions.

In research studies, Orexin B is used to explore how the brain stays awake, how it manages hunger and energy, and how it reacts to stress. Because it may target OX2R specifically, it may help researchers study brain activity related to arousal, sleep disorders, and metabolic disorders. 

What are the potential benefits of Orexin B?

In research studies, Orexin B has shown potential benefits, which include: 

• Scientists use Orexin B to investigate sleep disorders, such as narcolepsy and insomnia.
  
• Researchers indicate that it could enhance brain arousal and promote alertness.
  
• Orexin B is also being explored by researchers to investigate appetite control and eating disorders.
  
• Preclinical studies indicate that it could also treat neurodegenerative disorders like Alzheimer’s and Parkinson’s disease. 

Note: This product is intended for research purposes and is not approved for human use.

Research on Orexin B

Sleep and Wakefulness

• Orexin B may help researchers understand how the brain stays awake.
• It is often used in studies on narcolepsy, a disorder linked to low orexin levels. 
• It may also help explain insomnia and other sleep disturbances. 

However, more studies are required. 

Energy Balance and Metabolism

• Research shows that Orexin B may affect how the body uses energy. 
• It is used in studies on appetite regulation and eating disorders. 

Mood and Stress

• Orexin B is being studied for its possible role in anxiety, depression, and stress responses. 
• It may affect emotional behavior by acting on areas of the brain involved in mood. 

Neurodegenerative Diseases

• Some studies are exploring how Orexin B might relate to conditions like Alzheimer’s disease and Parkinson’s disease, due to its role in brain activity and sleep.

Addiction and Reward System

Researchers are also investigating how Orexin B may influence motivation, reward-seeking, and addictive behaviors. 

Where can I buy Orexin B online for research purposes?

If you are looking to buy Orexin B for research purposes, PureRawz is a trustworthy source.

We provide reference materials with every product we sell. A Certificate of Analysis is available for reference, providing information on identification, purity, and concentration.

Is it legal?

Orexin B is considered legal for research purposes. It is not approved by the FDA for human or veterinary use. Further studies are required to determine its effectiveness.

FAQs

What is the difference between Orexin A and Orexin B?

Orexin A and Orexin B are neuropeptides produced in the hypothalamus that regulates weakness, energy balance, and arousal. Orexin A may bind to both OX1R and OX2R receptors, while Orexin B is more selective for OX2R, making it particularly useful in studying sleep disorders like narcolepsy. 

What is the main function of Orexin B in research?

It is used to study brain functions like sleep, appetite, energy use, and stress response. 

Is Orexin B approved for human consumption?

No, Orexin B is used for research purposes. It is not approved by the FDA for human or veterinary use. 

Are there any potential side effects of Orexin B?

Since Orexin B is a research compound, many of its side effects are unknown. However, potential side effects include change in appetite, stress, or sleep disturbances. 

What is the shelf life on Orexin B?

The shelf life of Orexin B is typically up to three months. However, its shelf life depends on the storage conditions.

How to store Orexin B?

It is best to store Orexin B in a cool, dry place away from direct sunlight. This helps extend the shelf life of the product. 

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human usage.