DHEA + Enclomiphene Citrate Stack


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DHEA + Enclomiphene Citrate Stack – Product Information

The DHEA + Enclomiphene Citrate Stack is a fascinating line of inquiry for future biological research. DHEA and Enclomiphene are two different chemicals, and this combination is meant to bring out strengths to comprehend possible synergies and applications

  • DHEA + Enclomiphene Citrate Stack consists of 25mg DHEA and 20mg Enclomiphene Citrate.
  • Tables are offered in 2 variants: 45mg for 30 tablets, totaling 1350mg, and 45mg for 60 tablets totaling 2700mg.

DHEA and Enclomiphene Citrate have the potential to work by synergistically supporting healthy exogenous testosterone and luteinizing hormone levels. By mildly stimulating estrogen receptors, Enclomiphene signals the body of subjects to produce testosterone. DHEA provides building blocks to potentially support maintaining testosterone levels already within normal ranges. Together, they can help encourage testosterone levels and sperm production in research settings.

Please note that these statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease or sperm counts. Purerawz sells DHEA + Enclomiphene Citrate for research purposes only.

CAS Number 53-43-0
Molar Mass 288.484 g/mol
Chemical Formula C19H28O2
IUPAC Name (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
Enclomiphene Citrate
CAS Number 7599-79-3
Molar Mass 598.1 g/mol
Chemical Formula C32H36ClNO8
IUPAC Name 2-[4-[(E)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid


What is DHEA + Enclomiphene Citrate?

DHEA + Enclomiphene Citrate is a potential research combination that has demonstrated anti-estrogen effects to optimally support healthy testosterone levels. Enclomiphene works by potentially mildly stimulating estrogen receptors in the pituitary gland, which may signal the body to produce more of its own testosterone and luteinizing hormone. DHEA has the potential to provide additional building blocks to maintain testosterone levels already within normal ranges. By working together synergistically, this product has the potential to encourage optimal testosterone in a research setting.


DHEA, or Dehydroepiandrosterone, is a steroid hormone produced naturally by the adrenal glands. It serves as a precursor that can be used to stimulate the synthesis of other crucial hormones, including testosterone and estrogen.

As mentioned above, the adrenal glands create the hormone dehydroepiandrosterone (DHEA). The male and female sex hormones, androgens and estrogens, are produced using DHEA. DHEA levels reach their peak at age 25, then gradually decrease as the human body ages. This results in numerous researchers attempting to investigate the potential of DHEA to aid in balanced hormone levels as a potential prescription fertility compound.

Researchers have questioned whether DHEA can act as a potential anti-aging solution given the levels of the hormone tends to drop with age. Low levels of DHEA have also been linked to memory loss, breast cancer, osteoporosis, and heart disease in older adult subjects.

Enclomiphene Citrate

Enclomiphene Citrate is an estrogen receptor modulator that is currently being studied for its potential applications in treating secondary hypogonadism. It has a molecular weight of 441.98 g/mol and acts as an anti-estrogen agent in the hypothalamus.

Enclomiphene Citrate is similar to clomiphene citrate, another anti-estrogenic compound. However, enclomiphene citrate has been shown to potentially stimulate the hypothalamic-pituitary-gonadal axis to increase the secretion of luteinizing hormone and follicle-stimulating hormone. This leads to an upregulation of testicular testosterone production.

In studies, enclomiphene citrate has been shown to increase testosterone levels into the normal range in male subjects with secondary hypogonadism without significantly impacting sperm counts. This makes it an attractive alternative treatment option for male test subjects struggling with low testosterone. More research is still needed, but the current data shows promise for enclomiphene as a therapeutic agent.

Possible Applications of DHEA + Enclomiphene Citrate

May increase muscle mass and strength

A 10-month, double-blind, placebo-controlled study found DHEA therapy combined with 4 months of weightlifting training potentially increased muscle strength and volume in elderly treatment groups compared to DHEA alone. This was associated with increased serum insulin-growth factor levels. [R]

May improve bone mineral density

Multiple studies have shown DHEA replacement therapy for 2 years increased spine bone mineral density in older adult subjects by up to 3.6%. This could potentially help mitigate age-related bone loss. [R]

May support fat-burning

DHEA potentially decreased fat mass by about 4% over 4 months in those with adrenal issues, according to one study. Additional research shows it may produce small fat reductions in older adult test subjects. [R]

May increase testosterone levels

Human clinical studies found enclomiphene citrate sustained a potential increase in testosterone over 3 months in hypogonadal men subjects, more so than the drug clomiphene. Animal test subjects research also showed superior testosterone-boosting effects. [R]

May benefit sexual function

One DHEA study resulted in 25 female test subjects with fertility issues having potentially improved in vitro fertilization outcomes, potentially producing more eggs and higher fertilization rates. This indicates potential benefits for reproductive function. [R]

May have antidepressant effects

A 2014 DHEA review concluded it could have potential as an antidepressant, particularly for minor or treatment-resistant depression, indicating mental health benefits. [R]

How Does DHEA + Enclomiphene Citrate Work?

The goal of combining DHEA and Enclomiphene Citrate is to safely and effectively increase endogenous testosterone levels. DHEA is a precursor hormone that can be converted into testosterone. Enclomiphene Citrate works by blocking estrogen signals at the pituitary gland, which causes an increase in luteinizing hormone and follicle-stimulating hormone production. These gonadotropin hormones then signal the testes to ramp up their natural testosterone synthesis.

So in essence, DHEA provides extra raw materials to support testosterone production, while Enclomiphene Citrate removes estrogen feedback that normally suppresses testosterone. Together, they aim to restore testosterone levels through natural pathways. This combined approach could mitigate side effect risk factors that can occur with direct testosterone treatment, like testicular shrinkage.

However, more research is still needed to determine optimal dosing strategies for combined DHEA and Enclomiphene therapy. The pharmacokinetics and overall long-term effectiveness need to be established as well.

Safety and Side Effects

While DHEA and Enclomiphene Citrate show potential benefits, more research is still needed to fully characterize the safety profile and potential side effects of using them in combination. Some things to keep in mind:

  • As with any hormone compound, there could be risks of unwanted side effects like headache, nausea, acne, hair loss, mood changes, or alterations in cholesterol levels and liver enzymes.
  • Since these compounds aim to increase testosterone levels in subjects, there is a potential risk of over-supplementing testosterone. This could negatively impact fertility or normal testicular function. Bloodwork monitoring is imperative.
  • Enclomiphene and DHEA could potentially have interactions with certain health conditions or medications, especially hormones, diabetes drugs, anticoagulants, and antidepressants.
  • The long-term safety of this combo needs further establishment. Issues, like increased cardiac risk factors or benign prostatic hyperplasia, could be theoretical when significantly elevating androgens.

In summary, while animal research and some clinical studies provide initial promising data, substantially more investigation is required to characterize the safety profile of combined Enclomiphene Citrate and DHEA supplementation. Anyone considering their use should first have a medical evaluation to weigh potential risks versus benefits for them.

Frequently Asked Questions

What is DHEA?

DHEA, or dehydroepiandrosterone, is an endogenous steroid hormone precursor that can be converted into testosterone and estrogen in the body. It is produced naturally by the adrenal glands.

How does Enclomiphene Citrate work?

Enclomiphene Citrate is a selective estrogen receptor modulator. It works by blocking estrogen signals at the pituitary gland, which causes an increase in luteinizing hormone and follicle-stimulating hormone secretion from the pituitary gland. This signals the testes to increase their endogenous testosterone production.

Can Enclomiphene Citrate potentially increase testosterone?

Yes, studies show Enclomiphene Citrate may potentially increase total testosterone and free testosterone levels in subjects. In clinical trials, enclomiphene citrate groups exhibited boosted T levels compared to placebo groups.

Does DHEA help with infertility?

Some research suggests DHEA supplementation may support female reproductive function and infertility. One study found DHEA therapy improved ovulation and assisted infertility participants in producing more eggs and achieving higher fertilization rates.

Where Can You Buy DHEA + Enclomiphene Citrate?

PureRawz is the best place to buy DHEA + Enclomiphene Citrate for sale.

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This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY.
All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).
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