Emoxypine Succinate – Product Information
- Emoxypine Succinate is offered in 5g powder.
Emoxypine Succinate is an extensively researched synthetic nootropic compound and derivative of Vitamin B6 with membrane-protective and antioxidant properties. It has the ability to improve GABA availability and as a result dopamine levels in the brain. Recent studies have found Emoxypine to improve the cognitive function and brain health of patients with mental impairments and disorders by increasing mitochondrial oxygen consumption. [R]
What is Emoxypine Succinate?
As mentioned above, Emoxypine belongs to a class of Anxiolytic chemical compounds when used as the succinate salt. It has a similar structure as pyridoxine which is a type of Vitamin B6.
Emoxypine as a nootropic compound developed in Russia by a company called PharmaSoft, does not have any specific medical uses authorized in the EU or the US, however, it is widely used in Russia.
Although some researchers claim its potentialÂ as a cognitive enhancer to sharpen attention and calm anxiety, its main research use is to elevate and regulate mood.
According to experimental evidence, the succinate ion and the 2-ethyl-6-methyl-3-hydroxypyridinium cation, both of which are present in emoxypine succinate, exert a combined action. While the 3-hydroxypyridine component significantly reduces the MAO-inhibiting activity, the succinate portion causes a loss in the MAO-stimulating impact. [R]
These compounds can be viewed as a very promising therapeutic approach in the treatment of metabolic illnesses brought on by endothelial dysfunction thanks to the presence of these moieties.
How Does Emoxypine Succinate Work?
The proposed mechanism of action is that Emoxypine succinate controls the activity of the catalase and glutathione peroxidase enzymes, which neutralizes hydrogen peroxide radicals. This action modulates the antioxidant defense system. It exhibits direct contact with the water- and lipophilic-soluble radicals found in the phospholipid membranes, and this activity may be used to prevent subsequent skin damage and provide a dermatoprotective effect on ischemic skin. [R]
Emoxypine Succinate Research Use
Emoxypine Succinate is an extensively researched synthetic compound. Below are some of the relevant findings.
Emoxypine Succinate and Memory
Emoxypine improved memory function in trials on animals when it had been compromised by a variety of causes, such as lack of sleep or chemical (scopolamine) assaults. [R]
Emoxypine research is in its early stages, similar to that of many other nootropics, with promising results in animal models but no study on its benefits in healthy humans.
Emoxypine has been shown to have positive effects, however, the research supporting these claims is scant and has little use to healthy people trying to enhance their memory.
Purerawz sells Emoxypine succinate powder for research purposes only.
Emoxypine Succinate on Nervousness and Anxiety
Emoxypine exhibited considerable positive effects on levels of anxiousness without having any sedative or memory-impairing side effects, according to a review of animal research. [R]
Emoxypine Succinate as Vascular Aid
Numerous studies on Emoxypine Succinate’sÂ vascular properties have shown that it can decrease platelet aggregation and delay blood clotting by activating the prostaglandin-thromboxane pathway or by modifying the activity and morphology of the platelets. [R] [R]
Emoxypine Succinate and Anti-Inflammatory Effects
Emoxypine succinateÂ has anti-ischemic properties according to clinical trials and experimental tests on skin ischemia. Aspartate transaminase and creatine phosphokinase activity decreased after mexidol, a form of emoxypine succinate,Â (25 mg/kg, 3 days) was administered to male albino rats used as an animal model. Mexidol’sÂ effect halted the advancement of skin necrosis along with a reduction in cytolysis. [R]
Emoxypine succinate controls the activity of the catalase and glutathione peroxidase enzymes, which neutralizes hydrogen peroxide radicals. This action modulates the antioxidant defense system. It exhibits direct contact with the water- and lipophilic-soluble radicals found in the phospholipid membranes, and this activity may be used to prevent subsequent skin damage and provide a dermatoprotective effect on ischemic skin. [R]
Emoxypine Succinate and Acute Ischemic Stroke
In 116 patients with ischemic stroke, the comparative effectiveness of ethylmethylhydroxypyridine succinate (Mexidol) in combination with thrombolytic treatment was examined. All patients were split into two groups; the group (46 patients) underwent mexidol-based thrombolysis, whereas the group (70 patients) received thrombolysis in conjunction with normal care.
These findings demonstrated the synergy between this single therapy and the substantially quicker normalization of acute indicators, which was connected with the degree of neurological insufficiency decrease.
The findings, therefore, demonstrated that synergistic therapy creates the necessary circumstances for both secondary brain damage prevention and neurological state restoration. [R]
Emoxypine Succinate and Neuroprotective Diseases
Emoxypine and its succinate derivative have demonstrated promising results in the treatment of numerous neurodegenerative illnesses (including Alzheimer’s, Parkinson’s, and Multiple Sclerosis), with the suppression of prooxidants in the mitochondria being the postulated mechanism of action.Â [R]
Since Emoxypine Succinate has been found to have such a strong antioxidant effect, it may be used to treat conditions brought on by free radical damage as it may regulate free radical oxidation.[R]
Additionally, according to clinical trials, Mexidol should be administered intravenously or intramuscularly, then orally, to treat neurological illnesses like neurodegenerative diseases, diabetic polyneuropathy, infectious neuropathies, endovascular surgery, and spinal dystrophy. [R]
Emoxypine Succinate and Depression
Emoxypine’s antidepressant effects have been extensively researched in animal models. The impact of the medication on reducing immobility was investigated in an experimental setup created by Volchegorskii et al.
Forced swimming was used to study the onset of immobility, and it was discovered that a single dose of 3-hydroxypyridine derivatives significantly decreased immobility. Emoxypine also contributed to a notable reduction in the duration of behavioral distress. Emoxypine exerts a strong anti-depressant effect in the animal model under study, according to experimental data. [R]
Emoxypine Succinate and Diabetes
Mexidol was found to considerably improve cognitive performance, and sleep patterns, and result in the stabilization of metabolic markers in a recent clinical trial to evaluate its effects in the management of diabetes mellitus in association with neurological conditions.
This study concludes that Mexidol (75 days of therapy) can be used as a potential adjunctive medication for patients with diabetes. [R]
Emoxypine Succinate and Addiction
Mexidol has also been suggested for the treatment of neurological conditions associated with addiction. Further study is required to demonstrate its uses in the management of neurological and cognitive deficits associated with addictive diseases. It has been proposed as a therapy strategy for addiction linked to the consumption of alcohol and narcotic drugs. [R]
Emoxypine succinate and Acute Kidney Injury (AKI)
In a study by Shchudrova et al., non-linear white rats were utilized as an animal model to examine the renoprotective effects of mexidol in combination with organospecific peptides. Numerous techniques were used to cause AKI, and it was shown that Mexidol and peptide treatment had a 100% survival rate in cases of rhabdomyosis-induced ischemia-perfusion AKI in the experimental group. [R]
Emoxypine Succinate and Heart Health
A recent study investigating the effect of the synthetic antioxidant emoxypine on the tonus of the coronary vessels found it to have anti-anginal effects by triggering repair procedures in the cardiac infarct zone. [R]
Mexidol was found to enhance the antioxidant defense system, reduce lipid buildup in the heart tissues, and prevent the development of cardiotoxicity in a preclinical study to evaluate its use in the management of cardiotoxicity in cases of acute pancreatitis. The study used an adult mongrel dog model. [R]
Is Emoxypine Succinate Safe?
Emoxypine succinate was very safe in 20 patients 125 mg three times daily for 20 days. [R]
Emoxypine succinate may not be safe to use for extended periods of time or in higher doses because there are so few studies on its effects in human participants.
Where to Buy Emoxypine Succinate Online
PureRawz is the best place to buy Emoxypine Succinate online.
In order to be the best SARMs supplier, we provide reference materials with every product we sell. Each of our SARMS comes with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.
We offer free worldwide shipping on all orders above $100. You can pay for your purchase through various methods, including PayPal and Bitcoin. Click on the âReviewsâ tab to check out what existing customers have to say about our products and great customer service.
In general, Emoxypine succinate is a very promising substance with a variety of potential advantages.
It has been observed to have a therapeutic effect in various areas, including the potential treatment of behavioral problems and the treatment of anxiety, receptor complexes, free radical oxidation, membrane protective properties, and anti-stress.