Buy Kanna For Sale (Full Spectrum Mesembrine Alkaloid) – Product Details
Kanna is a plant from the South African continent where it has been utilized for its natural antidepressant properties for hundreds of years. Research shows it may reliably elevate mood and relieve anxiety, depression, and stress.
Recent studies even confirm that Kanna has nootropic properties as it may have the ability to improve the cognitive function of the nervous system.
What is Kanna?
Kanna, or Sceletium Tortuosum, is a medicinal plant native to South Africa. It is a succulent, flowering plant and is a member of the Mesembrine family. Over the centuries, indigenous peoples have traditionally chewed this plant, used it as tea, smoked it, or snuffed it for benefits.
In recent years, case reports as well as double-blind studies have confirmed the antidepressant and anxiolytic effects of this plant. Furthermore, in one cell-based study, Kanna increased the expression of IL-10 in cells exposed to it. IL-10 is a cytokine that lowers inflammation. [R] [R] [R]
PureRawz sells Kanna for research purposes only and not for human consumption.
How does Kanna Work?
While its exact mechanism of action remains unknown, it has been reported that Kanna influences the amygdala (the region of the brain whose main function is regulating emotions), and inhibits the serotonin hormone as well as the phosphodiesterase 4 (PDE4) enzyme. [R]
In recent years, multiple case studies have been conducted on Kanna. This medicinal plant has also attracted a few animal studies and clinical trials. They have shown that Kanna may possesses anxiolytic, anti-inflammatory, and antidepressant properties.
However, in the evidence of large-scale, randomized clinical trials, the FDA hasn’t approved Kanna for any medical condition (or for internal or external use). It is recommended that you seek the advice of your health care professional to learn more about this plant.
1) Kanna and Mood
A double-blind, placebo-controlled study was conducted to study the effects of Kanna on anxiety-related activity in the amygdala. It was shown that when compared with placebo administration, Kanna reduced anxiety-related amygdala reactivity. [R]
In another randomized, double-blind, placebo-controlled trial, several patients taking Kanna reported feeling better in general, coping better with stressful situations, and sleeping better at night. Moreover, in a separate clinical trial, positive changes in mood and sleep were found. [R] [R]
2) Kanna and Pain Relief
In a rat study, mesembrine (Kanna extract) demonstrated analgesic properties without abuse liabilities. That mesembrine has analgesic activity isn’t surprising, given it has shown activity at δ2- and m- opioid receptors; agonists at these sites show analgesic effects. [R]
These findings suggest that mesembrine may be a useful analgesic.
3) Kanna and Inflammation & Depression
Recent evidence suggests that inflammation may contribute to many psychiatric disorders, particularly depression. Also, chronic exposure to increased inflammation is thought to drive changes in the brain that lead to depressive symptoms. [R]
An in vitro study was carried out to investigate the immunomodulatory effects of Kanna. The findings indicate that Kanna may treat systemic low-grade inflammation, and might be beneficial in the attenuation of cytokine-induced depression. [R]
4) Kanna and Cognition
A 2014 study set out to investigate the neurocognitive effects of Kanna extract (Zembrin) on normal healthy people. The study’s subjects were randomized to receive either a 25mg capsule of Zembrin or a placebo capsule once daily for 3 weeks. [R]
Results from the study demonstrate that Zembrin at a 25mg daily dosage significantly improved cognitive set flexibility. Positive changes in mood and sleep were also found.
What Are the Effects of Kanna?
Indigenous South African people have been using Kanna powder for centuries to elevate mood, cure abdominal pain, and reduce stress, tension, and anxiety. [R]
What Are the Differences Between Kanna and Kratom?
Kratom is a plant native to Southeast Asia whereas Kanna is primarily grown in South Africa. Both also have different active ingredients. While Mitragynine, an indole-based alkaloid, is the main active ingredient in kratom, mesembrine is the primary active ingredient in Kanna.
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Where to Buy Kanna Online
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Kanna has been used for centuries by indigenous South African tribes to get relief from pain, stress, anxiety, and tension. In the last few years, various studies have also confirmed this plant’s anxiolytic, antidepressant, and analgesic properties. However, these properties are yet to be evaluated by the FDA.
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