Description
What is Pregnanolone?
Pregnanolone is a neurosteroid naturally derived from progesterone. It is being studied for its interaction with GABA-A receptors. It has a potential role in modulating stress, mood, and neurological function in laboratory settings.
Researchers investigate Pregnanolone for its possible calming and anti-anxiety effects in lab models. It could also have neuroprotective properties in preclinical models.
Pregnanolone is strictly for research purposes. It is not approved for human or animal use.
Chemical Properties
IUPAC Name | (3α,5β)-3-hydroxypregnan-20-one |
CAS Number | 128-20-1 |
Molecular Formula | C21H34O2 |
Molecular Weight | 318.501 g/mol |
Appearance | White to off-white crystalline powder |
Purity | â¥98% |
Solubility | Soluble in ethanol, DMSO, and PEG; limited water solubility |
Storage | -20°C |
How does Pregnanolone work?
Preclinical studies suggest Pregnanolone may act through the following mechanisms:
- It may modulate the GABA-A receptor as a positive allosteric modulator in laboratory models.
- It could influence the central nervous system by promoting inhibitory neurotransmission.
- It may interact with neuroendocrine pathways. It is involved in mood, sleep, and cognitive function in test subjects.
These mechanisms are currently under investigation in laboratory research.
What are the potential research benefits of Pregnanolone?
In experimental models, researchers have studied Pregnanolone for its potential to:
- Support anti-anxiety and calming effects in animal models
- Promote neuroprotection in stress-related preclinical studies
- Modulate seizure thresholds in neurological research
- Improve sleep quality in sleep disturbance models
Note: This product is intended for research purposes only. It has not been approved by the FDA for human or veterinary use.
Research on Pregnanolone
Studies in rodent models have shown Pregnanolone to exert sedative and anxiolytic effects without the dependence risks seen in some other GABAergic agents.
In vitro studies also suggest that Pregnanolone may have neuroprotective effects under oxidative stress conditions.
Further research is needed to understand its full pharmacological profile.
Where can Pregnanolone be purchased for research use?
PureRawz is a trustworthy supplier if you’re looking to buy Pregnanolone for research. we have wide range of research Nootropic for sale with fast shipping.
Each purchase includes a reference-grade Certificate of Analysis. This document verifies the compound’s identity, purity, and concentration to support research compliance.
Is Pregnanolone legal?
Pregnanolone is legal for research in some regions. Researchers must follow local and institutional regulations for legal compliance.
FAQs
Is Pregnanolone safe for human use?
No. Pregnanolone is not approved for human or animal use. It is strictly for laboratory research.
What are the side effects of Pregnanolone?
Side effects have not been fully studied. Ongoing research in animal models aims to explore safety and tolerability.
What is the shelf life of Pregnanolone?
When stored properly at -20°C, Pregnanolone has a shelf life of up to 2 years.
How should Pregnanolone be stored?
Keep the compound in a cool, dry environment away from direct light. Use airtight containers to preserve stability.
Disclaimer
This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co
ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY. It is not intended for veterinary or human usage.
Arthur Barton –
Very pleased with the product, and as usual, customer service is excellent.
Evan –
Perfect for mood-stabilizing effects.