N-Acetyl Epithalon Amidate – Product Details
Epithalon is the synthetic form of the polypeptide epithalamin, also often written as epitalon. Studies have revealed that Epithalon may have the capacity to boost the cellular enzyme telomerase synthesis, which is crucial for determining cell fate and aging.
Purerawz also offers Epithalon as a stand-alone peptide and spray where you can find more information regarding this compound.
Pure Rawz sells N-Acetyl Epithalon Amidate for laboratory research use only.
|IUPAC NAme||(4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid|
What Is Epithalon?
Epithalon is a synthetic form of the polypeptide Epithalamin, which has been demonstrated to possibly lengthen the lives of rats and mice. According to a human investigation, patients using Epithalamin experienced a 1.6 – 1.8-fold reduction in mortality compared to the control group. [R] [R]
In the 1980s, epithalon was first found in Russia. It was discovered by Professor Vladimir Khavinson, who had previously recovered epithalamin from the pineal glands of cattle.
He developed a synthetic version of the natural polypeptide because it was challenging to extract it in big quantities.
Epitalon replicates the effects of epithalamin, according to research. For instance, Epitalon increases the life span of fruit flies and mice. In older rhesus monkeys, this synthetic peptide also reinstates the circadian cycles of melatonin and cortisol synthesis. [R]
How Does Epithalon Work?
May Boost Telomerase Production in the Body
According to research, each chromosome’s two ends contain the enzyme telomerase. By potentially increasing the telomerase production, it may be possible to stop the aging process. [R]
The telomeres, caps that shield the ends of chromosomes, are produced more frequently by telomerase. Telomeres shorten as cells divide, which finally causes cells to cease dividing and die. By promoting telomere lengthening, telomerase stops this reduction in some cells, including stem cells.
Potential to get rid of free radicals
According to an animal study, Epitalon peptide is a strong antioxidant that is comparable to melatonin and may promote longevity. [R]
In a different investigation, it was shown that the peptide preparations from the pineal gland (Epithalamin and Epitalon) may have antioxidant activities that, in some situations, surpass those of melatonin, a well-known ROS scavenger. [R]
May potentially regulate DNA.
Epithalon controls the expression of genes that are functionally associated with various cell systems, according to research. It has been demonstrated that this synthetic peptide interacts with DNA locations found in the promoter regions of the genes producing the signaling molecules CD5, IL-2, MMp2, and Tram1. [R]
What is N-Acetyl epitalon amidate?
Acetyl-Epitalon-Amidate is a reformulated form of Epitalon, a synthetic peptide that may have anti-aging and telomerase activation effects. The Acetyl and Amidated groups may improve the compound’s stability, bioavailability, and effectiveness.
What makes N-Acetyl Epitalon Amidate Peptide different from Epithalon?
The alterations to Epithalon change its half-life, stability, and effectiveness but not the peptide’s overall function. The natural peptide only undergoes two modifications: N-acetylation and amidation. Each one offers unique benefits that increase the potency of Epithalon and allow for slower dosing of the phosphate.
Acetylation is a typical, natural activity that takes place in many parts of the body. Additionally, it is a method employed by the pharmaceutical industry to help a substance get to the central nervous system. Acetylated molecules have a potentially higher chance of successfully crossing the blood-brain barrier (BBB).
Acetylation has been found to potentially boost the rate at which a compound passes the blood-brain barrier, increasing the intensity of the compound’s effects and helping to decrease the dosage needed to achieve a specific research outcome. As an illustration, aspirin is the altered form of salicylic acid. According to research, the addition of salicylic acid boosts the anti-inflammatory effects on the molecule.
Another naturally occurring process modification that has been adopted by the pharmaceutical industry to enhance the effectiveness of chemicals is amidation. Amidated proteins are less sensitive to protein oxolysis in the bloodstream. Additionally, they tend to bind more strongly to their receptors, making the mixture an excellent method of boosting a compound’s potency and effectiveness.
It is possible to enhance the amount of blood flowing into the central nervous system while protecting it from deterioration by using Epithalon via acetylation and amidation. The outcome is an enhanced potency when Epithalon is administered, as well as increased effectiveness when using the molecule, due to improved receptor binding. [R]
Where to Buy N-Acetyl Epithalon Amidate Online
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