Sunifiram (Tablets) – Product Details
Sunifiram is an experimental drug structurally related to Piracetam. In animal studies, it improved focus, alleviated cognitive deficits, and possessed potent anti-amnesia effects.
Preclinical research has further demonstrated that Sunifiram may affect pain sensitivity.
Pure Rawz sells Sunifiram for laboratory and research purposes only.
|Molar Mass||246.31 g/mol|
What is Sunifiram?
Sunifiram (DM-235) is an AMPAkine drug (acts via AMPA receptors). It is a synthetic derivative of Piracetam and has a somewhat similar chemical structure. Still, despite having comparable anti-amnesic effects, Sunifiram is 4 times more potent than Piracetam. [R][R]
Sunifiram was originally developed to treat the symptoms of cognitive decline in Alzheimer’s disease patients. However, due to the lack of funding, no human trials were conducted to investigate its effects. All the evidence about its effects comes from animal studies. [R]
These preclinical studies show that Sunifiram is capable of enhancing memory and learning, reducing pain sensitivity, and affecting wakefulness and/or sleep.
Furthermore, it has been found that Sunifiram might reverse surgically-induced impairments in memory [R][R][R][R]
How does Sunifiram Work?
Although its exact working mechanism remains unknown, Sunifiram has been shown to:
- Stimulate the release of acetylcholine. In one animal study, Sunifiram reportedly increased acetylcholine release. Another preclinical study showed it blocked the effects of scopolamine, a drug that blocks acetylcholine release. [R][R]
- Activate AMPA receptors. Results from a mice study suggest that Sunifiram activates the AMPA-mediated neurotransmission system. Plus, it may block AMPA receptor activation by drugs that suppress the activity of AMPA receptors. [R]
- Regulate glucose uptake. Authors of a cell-based study report that Sunifiram may increase glucose uptake at a lower dose and increase it at a mega dose. [R]
- Activate NDMA glutamate receptors. Two cell-based studies suggest how Sunifiram may activate NDMA glutamate receptors. That is, by promoting the release of the neurotransmitter glutamate, which is proven to bind to glutamate receptors. [R][R]
What follows is a summary of the existing clinical research on Sunifiram. The information given in this section is for educational purposes only and doesn’t constitute medical advice. Speak to a medical health professional to get a qualified Sunifiram review.
1) Sunifiram and Memory
A preclinical study has reported that Sunifiram partially reversed surgically-induced impairments in memory in mice. It also reduced long-term potentiation. LTP is one of the main mechanisms in synaptic plasticity and plays a vital role in the ability to acquire, encode, and store memories. [R]
Two animal studies reported that Sunifiram counteracted experimentally-induced memory impairments (amnesia) in mice caused by other drugs. These drugs included scopolamine, clonidine, baclofen, and mecamylamine. [R][R]
2) Sunifiram and Learning
In one animal study involving mice, small doses of Sunifiram (0.01 mg/kg of body weight) increased the rate at which mice learned how to avoid shocks. The enhanced learning ability was measured using a behavioral task referred to as the passive avoidance test. [R]
According to another animal study, Sunifiram dosing (0.1 mg/kg body weight) reportedly increased the rate at which mice learned how to recognize social partners after brief interactions.
This test measured the learning ability using a task called the behavioral learning test. [R]
3) Sunifiram and Pain Sensitivity
Only one animal study has investigated the effects of Sunifiram on pain sensitivity.
The study investigated how mice responded to heat-related pain after being administered Sunifiram. A medium dose of Sunifiram (0.01 mg/kg) was reported to induce a mild pain-blocking effect in the mice. However, at a high as well as at a low dose, much weaker effects were reported. [R]
4) Sunifiram and Wakefulness
Evidence from one mice study indicated that Sunifiram may promote wakefulness. [R]
In the study, Sunifiram was reported to counteract the sleep-promoting effects of another drug. More specifically, animals treated with this research chemical slept less than their counterparts in the control group. [R]
Where to Buy Sunifiram?
Pure Rawz is the best place to buy the highest-quality Sunifiram online.
In order to be the best supplier of research chemicals, we provide reference materials with every product we sell. All of our products come with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.
We offer free international shipping on all orders above $100. You can pay for your purchase through various methods, including PayPal and Bitcoin.
We sell Sunifiram powder and tablet formulations for laboratory and research purposes only.
Sunifiram is an experimental research chemical derived from Piracetam. It has significantly greater potency than Piracetam and has demonstrated the ability to reduce pain sensitivity, reverse memory impairments (amnesia) and enhance learning in animal studies.
However, due to the absence of human studies, Sunifiram hasn’t been approved by any country or regulatory agency worldwide. It is thus unknown whether it could replicate the above effects in humans. Pure Rawz sells Sunifiram for laboratory and research use only.
It works great – you really notice the difference. You can feel your brain focus, instead of having one hundred things zooming by without any action.
I bought this to help my mom and the results are amazing – it has surely started helping to reverse her memory degeneration.
Tommy N –
My results were great on my rat, I am definitely trying more
This stuff is incredible. It allows me to focus on projects like nothing I’ve ever taken. I suffer from mild ADHD, and this stuff is the bomb on helping me stay focused. Good job team purerawz!
Mandy Robertson –
Ross Haren –
Keith Cook –
The quality of this Sunifiram is top notch. Definitely worth the price.
Jairo Nolan –
I received my order in 5 days, which is very reasonable for standard shipping. Thank you
Bobby Roberts –
I have more energy, think more clearly, and have a better memory overall. This is wonderful. Tried many and none gave me the results of this.
I am very happy with what I have received, time to test it out and see how well it works.
Keith Mendez –
My focus has improved a lot.
Keeps me sharp all day. Great product.
M. K. Rohan –
Sunifiram works really well with nootropics in my daily stack. Service was fast and Purerawz always has quality safe products that work.